Neural crest-derived stem cells display a wide variety of characteristics.

abstract：:Exposure of cells to ionizing radiation (IR) determines cellular lesions, such as DNA and membrane damage, which involve a coordinate network of signal transduction pathways responsible for resistance to or delay of apoptosis, depending on cell type and administered dose. Since, after IR exposure, the apoptotic profil...

journal_title：Journal of cellular biochemistry

authors： Cataldi A,Rapino M,Centurione L,Sabatini N,Grifone G,Garaci F,Rana R

更新日期：2003-08-01 00:00:00

abstract：:Colorectal cancer is the third most common cancer with a 5-year survival rate of less than 10%. It is caused by alterations of multiple signal pathways which are affected by both genetic and environmental factors. In some cases, EGFR is important in the carcinogenesis of colorectal cancer suggesting anti-EGFR therapy ...

journal_title：Journal of cellular biochemistry

authors： Chen J,Huang XF,Katsifis A

更新日期：2010-12-01 00:00:00

abstract：:To investigate changes in chromatin organization associated with DNA replication during the first stages of development of the sea urchin Tetrapygus niger, we compared micrococcal nuclease (MNase) digestion patterns of chromatin from zygotes harvested during the first S phase and from unfertilized eggs. We observed th...

journal_title：Journal of cellular biochemistry

authors： Imschenetzky M,Puchi M,Gutierrez S,Montecino M

更新日期：1995-10-01 00:00:00

abstract：:Rad51-mediated homologous recombination (HR) is essential for maintenance of genome integrity. The Xrcc3 protein functions in HR DNA repair, and studies suggest it has multiple roles at different stages in this pathway. Defects in vertebrate XRCC3 result in elevated levels of spontaneous and DNA damage-induced chromos...

journal_title：Journal of cellular biochemistry

authors： Forget AL,Bennett BT,Knight KL

更新日期：2004-10-15 00:00:00

abstract：:Amplification of MYCN is one of the most important prognostic markers for neuroblastoma and is correlated with rapid tumor progression and poor prognosis. MYCN belongs to the Myc/Max/Mad/Mnt network of proteins that regulate proliferation, apoptosis, and differentiation. It is well established that MYCN is downregulat...

journal_title：Journal of cellular biochemistry

authors： Smith AG,Popov N,Imreh M,Axelson H,Henriksson M

更新日期：2004-08-15 00:00:00

abstract：:Despite the historical use of estrogens in the treatment of prostate cancer (PCa) little is known about their direct biological effects on the prostate, their role in carcinogenesis, and what mechanisms mediate their therapeutic effects on PCa. It is now known that estrogens alone, or in synergism with an androgen, ar...

journal_title：Journal of cellular biochemistry

authors： Ho SM

更新日期：2004-02-15 00:00:00

abstract：:The bone marrow provides a protective environment for acute myeloid leukemia (AML) cells that often allows leukemic stem cells to survive standard chemotherapeutic regimens. Targeting these leukemic stem cells within the bone marrow is critical for preventing relapse. We recently demonstrated that SDF-1, a chemokine a...

journal_title：Journal of cellular biochemistry

authors： Kremer KN,Dudakovic A,McGee-Lawrence ME,Philips RL,Hess AD,Smith BD,van Wijnen AJ,Karp JE,Kaufmann SH,Westendorf JJ,Hedin KE

更新日期：2014-06-01 00:00:00

abstract：:Garlic is known as a potent spice and a medicine with broad therapeutic properties ranging from antibacterial to anticancer, antidiabetic, and anticoagulant. Two major proteins of 40 KD and 14 KD constituting approximately 96% of total garlic proteins have been recently purified at our Institute. This immunocytochemic...

journal_title：Journal of cellular biochemistry

authors： Wen GY,Mato A,Wisniewski HM,Malik MN,Jenkins EC,Sheikh AM,Kim KS

更新日期：1995-08-01 00:00:00

abstract：:Lung cancer (LC) is the second common cancer for both women and men all over the world. Unfortunately, the number of LC deaths is increasing rapidly each year so early diagnosis of LC can be lifesaving. MicroRNAs are involved in multiple processes, such as cell differentiation, transcription, inflammation, proliferati...

journal_title：Journal of cellular biochemistry

authors： Asghariazar V,Sakhinia E,Mansoori B,Mohammadi A,Baradaran B

更新日期：2019-12-01 00:00:00

abstract：:Previous studies related impaired myocardial microcirculation in diabetes to oxidative stress and endothelial dysfunction. Thus, this study was aimed to determine the effect of up-regulating pAMPK-pAKT signaling on coronary microvascular reactivity in the isolated heart of diabetic mice. We measured coronary resistanc...

journal_title：Journal of cellular biochemistry

authors： Kusmic C,L'abbate A,Sambuceti G,Drummond G,Barsanti C,Matteucci M,Cao J,Piccolomini F,Cheng J,Abraham NG

更新日期：2010-04-01 00:00:00

abstract：:A chimeric long terminal repeat-thymidine kinase (LTR-tk) gene has been used to define the sequence requirements for glucocorticoid induction of gene expression. The original LTR-tk gene contains an entire mouse mammary tumor virus (MMTV) LTR preceding the tk gene. This gene can be expressed in a hormone-responsive fa...

journal_title：Journal of cellular biochemistry

authors： Groner B,Herrlich P,Kennedy N,Ponta H,Rahmsdorf U,Hynes NE

更新日期：1982-01-01 00:00:00

abstract：:The higher ordered structure of the chicken alpha 2(1) procollagen gene was analyzed in chromatin isolated from expressing (lung) and nonexpressing (reticulocyte and erythrocyte) tissues. Digestion of DNA with methylation sensitive restriction endonucleases revealed that this gene was methylated in all tissues examine...

journal_title：Journal of cellular biochemistry

authors： Truter SL,Parker MI

更新日期：1994-02-01 00:00:00

abstract：:The type 2 diabetes is one of the major global health issues that affects millions of people. This study evaluated the antidiabetic activity of aqueous extracts (AECP) and methanol extracts (MECP) from Ceiba pentandra trunk bark on an experimental model of type 2 diabetes (T2D). This model was induced in rats by the c...

journal_title：Journal of cellular biochemistry

authors： Fofie CK,Katekhaye S,Borse S,Sharma V,Nivsarkar M,Nguelefack-Mbuyo EP,Kamanyi A,Singh V,Nguelefack TB

更新日期：2019-02-14 00:00:00

abstract：:Tumor cells display different bioenergetic profiles when compared to normal cells. In the present work we showed metabolic reprogramming by means of inhibitors of histone deacetylase (HDACis), sodium butyrate and trichostatin A in breast cancer cells representing different stages of aggressiveness and metabolic profil...

journal_title：Journal of cellular biochemistry

authors： Rodrigues MF,Carvalho É,Pezzuto P,Rumjanek FD,Amoêdo ND

更新日期：2015-05-01 00:00:00

abstract：:Diclofenac is the most commonly used phenylacetic acid derivative non-steroidal anti-inflammatory drug (NSAID) that demonstrates significant analgesic, antipyretic, and anti-inflammatory effects. Several epidemiological studies have demonstrated anti-proliferative activity of NSAIDs and examined their apoptotic induct...

journal_title：Journal of cellular biochemistry

authors： Amanullah A,Upadhyay A,Chhangani D,Joshi V,Mishra R,Yamanaka K,Mishra A

更新日期：2017-05-01 00:00:00

abstract：:The objective of this study was to test the hypothesis that extracellular matrix (ECM) would alter the endoplasmic reticulum (ER) stress response of chondrocytes. Chondrocytes were isolated from calf knees and maintained in monolayer culture or suspended in collagen I to form spot cultures (SCs). Our laboratory has sh...

journal_title：Journal of cellular biochemistry

authors： Nugent AE,McBurney DL,Horton WE Jr

更新日期：2011-04-01 00:00:00

abstract：:Necdin is a growth suppressor expressed predominantly in postmitotic neurons. The necdin gene is involved in the etiology of the genomic imprinting-associated neurodevelopmental disorder Prader-Willi syndrome and belongs to the MAGE gene family. All the MAGE family proteins contain a large homology domain termed the M...

journal_title：Journal of cellular biochemistry

authors： Taniura H,Kobayashi M,Yoshikawa K

更新日期：2005-03-01 00:00:00

abstract：INTRODUCTION:Pancreatic adenocarcinoma (PAAD) is one of the most fatal cancers in the world for early metastasis, extensive invasion, and poor prognosis with a 5-year survival rate less than 5%. However, the underlying mechanisms are poorly understood. Therefore, it is urgent to explore molecular markers for early diag...

journal_title：Journal of cellular biochemistry

authors： Yang Y,Wang Y,Liu S,Zhao X,Jia R,Xiao Y,Zhang M,Li X,Li J,Wang W

更新日期：2018-11-28 00:00:00

abstract：:We previously reported that 1α,25-dihydroxy-vitamin D(3) [1α,25(OH)(2)D(3)] induces non-transcriptional rapid responses through activation of Src and MAPKs in the skeletal muscle cell line C2C12. In the present study we investigated the modulation of Akt by the secosteroid hormone in C2C12 cells at proliferative stage...

journal_title：Journal of cellular biochemistry

authors： Buitrago CG,Arango NS,Boland RL

更新日期：2012-04-01 00:00:00

abstract：:Receptor activator of NF-kappaB ligand (RANKL) is a critical osteoclastogenic factor that is expressed on bone marrow stromal/preosteoblast cells. Most bone resorption stimuli induce osteoclast formation by modulating RANKL expression in these cells. However, little is known about the mechanisms regulating RANKL gene ...

journal_title：Journal of cellular biochemistry

authors： Sundaram K,Mani SK,Kitatani K,Wu K,Pestell RG,Reddy SV

更新日期：2008-04-15 00:00:00

abstract：OBJECTIVE:This study aimed to investigate the relationship between angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism and to understand sudden cardiac arrest (SCA) in the Chinese population. METHODS:In this study, 232 patients were divided into the SCA group and the coronary disease group with c...

journal_title：Journal of cellular biochemistry

authors： Liu A,Wang S,Zhang C,Sun D,Song X

更新日期：2019-03-01 00:00:00

abstract：:We have examined the composition and ultrastructure of the nuclear periphery during in vitro myogenesis of the rat myoblast cell line, L6E9. Immunofluorescence labelling and immunoblotting showed that lamins A/C and B were all present in undifferentiated cells, but that they increased significantly before extensive ce...

journal_title：Journal of cellular biochemistry

authors： Chaly N,Munro SB,Swallow MA

更新日期：1996-07-01 00:00:00

abstract：:Lysozyme is expressed in serous, but not mucous, cells of the tracheobronchial glands and thereby constitutes a marker of the serous cell lineage in these glands. To identify DNA regulatory elements and transcription factors mediating the commitment of progenitor cells to the serous cell lineage, we have characterized...

journal_title：Journal of cellular biochemistry

authors： Kai H,Takeuchi K,Ohmori H,Li JD,Gallup M,Basbaum C

更新日期：1996-06-01 00:00:00

abstract：:Osteosarcoma (OS) is a highly aggressive bone tumor with a poor prognosis. MicroRNAs are revealed to exerts essential roles in the carcinogenesis and tumor invasion of OS. But, the function of miR-1296-5p and its related mechanism in OS progression have not yet been studied. This study discovered the levels of miR-129...

journal_title：Journal of cellular biochemistry

authors： Wang L,Hu K,Chao Y,Wang X

更新日期：2020-02-01 00:00:00

abstract：:Scribble (Scrib) is a large multi-domain cytoplasmic protein that was first identified through its requirement for the establishment of epithelial polarity. We tested the hypotheses that Scrib asssociates with the basolateral membrane via multiple domains, binds specific protein partners, and is part of a multimeric c...

journal_title：Journal of cellular biochemistry

authors： Kallay LM,McNickle A,Brennwald PJ,Hubbard AL,Braiterman LT

更新日期：2006-10-01 00:00:00

abstract：OBJECTIVES:This study is aimed to explore the functions of long noncoding RNA (lncRNA) HEIH on the proliferation as well as metastasis of non-small cell lung cancer (NSCLC). METHODS:HEIH was shown to be increased in NSCLC by a microarray study on lncRNA profiling. We detected the expression of HEIH in different human ...

journal_title：Journal of cellular biochemistry

authors： Jia K,Chen F,Xu L

更新日期：2019-03-01 00:00:00

abstract：:Macromolecules are sulfated during the vegetative growth of Dictyostelium discoideum. A characterisation of the structures of sulfated oligosaccharides associated with these macromolecules indicates that the oligosaccharides are heterogeneous. Endoglycosidase and pronase digestion were used with gel-filtration chromat...

journal_title：Journal of cellular biochemistry

authors： Davis SJ

更新日期：1988-10-01 00:00:00

abstract：:Cervical cancer is one of the leading killers for female worldwide. Nevertheless, the less knowledge of molecular mechanism for cervical cancer limited the improvement of treatment effects. High-mobility group box 2 (HMGB2) belongs to the HMGB family, which could play diverse roles in cell proliferation. This work mai...

journal_title：Journal of cellular biochemistry

authors： Zhang P,Lu Y,Gao S

更新日期：2019-10-01 00:00:00

abstract：:Large doses of bone morphogenetic protein 2 (BMP2) are used clinically to induce bone formation in challenging bone defects. However, complications after treatment include swelling, ectopic bone formation, and adjacent bone resorption. While BMP2 can be effective, it is important to characterize the mechanism of the d...

journal_title：Journal of cellular biochemistry

authors： Hyzy SL,Olivares-Navarrete R,Schwartz Z,Boyan BD

更新日期：2012-10-01 00:00:00

abstract：:Butyrate inhibits growth of lung cancer. However, the molecular mechanism is still unclear. Here we profiled miRNAs that responded to sodium butyrate(NaB) stimulation in A549 cells, a non-small cell lung cancer cell line, using microarray. We found 33 up-regulated microRNAs and 22 down-regulated microRNAs (log2 ≥1.5 f...

journal_title：Journal of cellular biochemistry

authors： Xiao X,Cao Y,Chen H

更新日期：2018-04-01 00:00:00