Long noncoding RNA HEIH promotes the proliferation and metastasis of non-small cell lung cancer.

abstract：:Whitmania pigra is a unique, fluid-sucking ectoparasite and an anticoagulant medical leech. The codon usage bias (CUB) is the nonuniform usage of synonymous codons in which some codons are more preferred than others. Here, we performed a comprehensive analysis of CUB of genes in W. pigra, analyzing 140 780 transcripts...

journal_title：Journal of cellular biochemistry

authors： Khan MS,Guan DL,Ma LB,Xie JY,Xu SQ

更新日期：2019-06-01 00:00:00

abstract：:We previously reported that prostaglandin F2 alpha (PGF2 alpha) receptor is coupled to pertussis toxin (PTX)-sensitive GTP-binding protein (G protein) in osteoblast-like MC3T3-E1 cells [Miwa et al. (1990): Biochem Biophys Res Commun 171:1229-1235]. In the present study, we examined the effect of PGF2 alpha on the acti...

journal_title：Journal of cellular biochemistry

authors： Kozawa O,Suzuki A,Kotoyori J,Tokuda H,Watanabe Y,Ito Y,Oiso Y

更新日期：1994-07-01 00:00:00

abstract：:Phosphoinositide 3-kinase proteins are composed by a catalytic p110 subunit and a regulatory p85 subunit. There are three classes of PI3K, named class I-III, on the bases of the protein domain constituting and determining their specificity. The first one is the best characterized and includes a number of key elements ...

journal_title：Journal of cellular biochemistry

authors： Feola A,Cimini A,Migliucci F,Iorio R,Zuchegna C,Rothenberger R,Cito L,Porcellini A,Unteregger G,Tombolini V,Giordano A,Di Domenico M

更新日期：2013-09-01 00:00:00

abstract：:Operons subject to catabolite repression (CR) in the gram-positive bacteria appear to be transcriptionally regulated by negative acting catabolite repressors. Cis elements within the promoter regions of a few CR operons have been identified as the target sequences for these repressors. It has also been proposed that s...

journal_title：Journal of cellular biochemistry

authors： Stewart GC

更新日期：1993-01-01 00:00:00

abstract：:In the interphase nucleus of metazoan cells DNA is organized in supercoiled loops anchored to a nuclear matrix (NM). DNA loops are operationally classified in structural and facultative. Varied evidence indicates that DNA replication occurs in replication foci organized upon the NM and that structural DNA loops may co...

journal_title：Journal of cellular biochemistry

authors： Castillo-Mora RC,Aranda-Anzaldo A

更新日期：2012-07-01 00:00:00

abstract：:Bladder cancer-associated transcript 1 (BLACAT1) is a novel identified long noncoding RNA (lncRNA) in bladder cancer, and has been suggested to function as an oncogenic lncRNA in several types of human cancer. However, its involvement in the progression of small-cell lung cancer (SCLC) remained unknown. The aim of our...

journal_title：Journal of cellular biochemistry

authors： Chen W,Hang Y,Xu W,Wu J,Chen L,Chen J,Mao Y,Song J,Song J,Wang H

更新日期：2018-09-11 00:00:00

abstract：:Transplantation of functional insulin-producing cells (IPCs) provides a novel mode for insulin replacement, but is often accompanied by many undesirable side effects. Our previous studies suggested that IPCs could not mimic the physiological regulation of insulin secretion performed by pancreatic beta cells. To obtain...

journal_title：Journal of cellular biochemistry

authors： Shi Q,Luo S,Jia H,Feng L,Lu X,Zhou L,Cai J

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:The impact of aberrant expression of miRNAs, small noncoding RNAs of 19 to 23 nucleotide, has been reported in different types of cancer, such as breast cancer. Authors aim to investigate the role of circulating miRNA-335 as a diagnostic and prognostic marker for breast cancer. MATERIALS AND METHODS:miRNA-3...

journal_title：Journal of cellular biochemistry

authors： Swellam M,Mahmoud MS,Hashim M,Hassan NM,Sobeih ME,Nageeb AM

更新日期：2019-06-01 00:00:00

abstract：:In previous publications, we showed that extracellular glycosaminoglycans reduced the membrane potential, caused cell blebbing and swelling and decreased the intracellular pH independently of cell surface receptors. These phenomena were explained by Donnan effects. The effects were so large that they could not be attr...

journal_title：Journal of cellular biochemistry

authors： Hagenfeld D,Kathagen N,Prehm P

更新日期：2014-07-01 00:00:00

abstract：:Despite its recognition as the most prevalent HIV associated cancer, speculation still abounds regarding the pathogenesis of AIDS-related Kaposi's sarcoma (AIDS-KS). However, it has been established that both cytokines, e.g. IL-6, and HIV-associated products, e.g., Tat, are integral in AIDS-KS cellular proliferation. ...

journal_title：Journal of cellular biochemistry

authors： Mallery SR,Bailer RT,Hohl CM,Ng-Bautista CL,Ness GM,Livingston BE,Hout BL,Stephens RE,Brierley GP

更新日期：1995-11-01 00:00:00

abstract：:Epigallocatechin-3-gallate (EGCG), the major green tea polyphenol, can reach the brain following oral intake and could thus act as an anti-tumoral agent targeting several key steps of brain cancer cells invasive activity. Because integrin-mediated extracellular matrix recognition is crucial during the cell adhesion pr...

journal_title：Journal of cellular biochemistry

authors： Pilorget A,Berthet V,Luis J,Moghrabi A,Annabi B,Béliveau R

更新日期：2003-11-01 00:00:00

abstract：:We investigated the early effects of the anti-idiotypic antibody (clone 1D5), which recognized the estrogen receptor (ER), on cytosolic free calcium concentration ([Ca2+]i) and its long term effects on creatine kinase (CK) specific activity in female human and rat osteoblasts. These actions were compared to the known ...

journal_title：Journal of cellular biochemistry

authors： Sömjen D,Kohen F,Lieberherr M

更新日期：1997-04-01 00:00:00

abstract：:Leptin, a hormone primarily produced by adipocytes, contributes to the regulation of bone health by modulating bone density, growth and adiposity. Upon leptin binding, multiple sites of the long form of the leptin receptor (LepRb) are phosphorylated to trigger activation of downstream signaling pathways. To address th...

journal_title：Journal of cellular biochemistry

authors： McCabe IC,Fedorko A,Myers MG Jr,Leinninger G,Scheller E,McCabe LR

更新日期：2019-03-01 00:00:00

abstract：:Both clinical and experimental evidence indicates that AIDS-related Kaposi's sarcoma (AIDS-KS) has a multifactorial pathogenesis with factors such as HIV viral load, latent virus induction, and opportunistic infections contributing to disease progression. However, a consistent feature that unites these apparently dive...

journal_title：Journal of cellular biochemistry

authors： Mallery SR,Landwehr DJ,Ness GM,Clark YM,Hohl CM

更新日期：1998-03-01 00:00:00

abstract：:Altered expression of ABH blood group substances is a common feature of human colorectal carcinoma, yet it remains unclear how these structural changes influence the biological properties of tumor cells. Azoxymethane-induced rat colon tumors display many features of the human disease, thereby providing a potentially u...

journal_title：Journal of cellular biochemistry

authors： Laferté S,Prokopishyn NL,Moyana T,Bird RP

更新日期：1995-01-01 00:00:00

abstract：:Bone formation is under the control of a set of transcription factors. Ids are inhibitory helix-loop-helix (HLH) transcription factors and expression of Id genes in osteoblasts is under the control of calciotropic agents such as BMP and vitamin D. However, the function of Ids during bone formation in vivo has not yet ...

journal_title：Journal of cellular biochemistry

authors： Maeda Y,Tsuji K,Nifuji A,Noda M

更新日期：2004-10-01 00:00:00

abstract：:Roscovitine (ROSC), a selective cyclin-dependent kinase (CDK) inhibitor, arrests human estrogen receptor-α (ER-α) positive MCF-7 breast cancer cells in the G(2) phase of the cell cycle and concomitantly induces apoptosis via a p53-dependent pathway. The effect of ROSC is markedly diminished in MCF-7 cells maintained i...

journal_title：Journal of cellular biochemistry

authors： Węsierska-Gądek J,Gritsch D,Zulehner N,Komina O,Maurer M

更新日期：2011-03-01 00:00:00

abstract：:In addition to its roles in sugar metabolism, fructose-1,6-bisphosphate aldolase (aldolase) has been implicated in cellular functions independent from these roles, termed "moonlighting functions." These moonlighting functions likely involve the known aldolase-actin interaction, as many proteins with which aldolase int...

journal_title：Journal of cellular biochemistry

authors： Ritterson Lew C,Tolan DR

更新日期：2013-08-01 00:00:00

abstract：:Chromatin immunoprecipitation (ChIP) is an important technique for studying protein-DNA interactions. Whole genome ChIP methods have enjoyed much success, but are limited in that they cannot uncover important long-range chromatin interactions. Chromosome conformation capture (3C) and related methods are capable of det...

journal_title：Journal of cellular biochemistry

authors： Fullwood MJ,Ruan Y

更新日期：2009-05-01 00:00:00

abstract：:The inhibitor of growth (ING) family of proteins is an evolutionarily conserved family, with members present from yeast to humans. The mammalian ING proteins are candidate tumor suppressor proteins and accordingly can cooperate with p53 to arrest proliferation and induce apoptosis. ING proteins are also reported to fu...

journal_title：Journal of cellular biochemistry

authors： Shi X,Gozani O

更新日期：2005-12-15 00:00:00

abstract：BACKGROUND:Exposure to pesticides is associated with an increase in the incidence of cancer. We aimed to investigate the association of serum organochlorine pesticides (OCPs) and organophosphorus pesticides (OPs) levels and GSTM1/GSTT1 gene polymorphism with bladder cancer (BC). METHODS:This study was performed on 57 ...

journal_title：Journal of cellular biochemistry

authors： Mortazavi N,Asadikaram G,Ebadzadeh MR,Kamalati A,Pakmanesh H,Dadgar R,Moazed V,Paydar P,Fallah H,Abolhassani M

更新日期：2019-09-01 00:00:00

abstract：:Evidence indicates that agonists of neuronal nicotinic receptors (nAChRs), including nicotine, can induce neuroprotective and anti-apoptotic effects in the CNS. To study these mechanisms, the present study focused on nicotine-mediated modulation of the extracellular regulated kinase 1 and 2 (ERK1/2) pathway in culture...

journal_title：Journal of cellular biochemistry

authors： Toborek M,Son KW,Pudelko A,King-Pospisil K,Wylegala E,Malecki A

更新日期：2007-02-01 00:00:00

abstract：:Platelet-derived growth factor-D (PDGF-D) can enhance invasion and metastasis in several human malignancies. Although several studies have been performed to investigate the association between clinicopathological characteristics and prognosis in epithelial ovarian cancer (EOC), the mediation effect of PDGF-D on above-...

journal_title：Journal of cellular biochemistry

authors： Yang C,Zhang M,Cai Y,Rong Z,Wang C,Xu Z,Xu H,Song W,Hou Y,Lou G

更新日期：2019-01-16 00:00:00

abstract：:Pre-adipocyte 3T3-L1 cells, after an appropriate induction stimulus, proceed through a defined change in morphology as differentiation progresses. Transforming growth factor beta 1 (TGF beta 1) is able to block the morphological and biochemical changes which occur with differentiation of these cells if given within 36...

journal_title：Journal of cellular biochemistry

authors： Bortell R,Owen TA,Ignotz R,Stein GS,Stein JL

更新日期：1994-02-01 00:00:00

abstract：:The vitamin D receptor (VDR) binds to and mediates the effects of the 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)) hormone to alter gene transcription. A newly recognized VDR ligand is the carcinogenic bile acid, lithocholic acid (LCA). We demonstrate that, in HT-29 colon cancer cells, both LCA and 1,25(OH)(2)D(3) ind...

journal_title：Journal of cellular biochemistry

authors： Jurutka PW,Thompson PD,Whitfield GK,Eichhorst KR,Hall N,Dominguez CE,Hsieh JC,Haussler CA,Haussler MR

更新日期：2005-04-01 00:00:00

abstract：:Cancer stem cells (CSCs) are tumoral cells which have stem features such as self-renewal, high migration capacity, drug resistance, high proliferation abilities. In the last 10 years the pathological meaning and the existence of CSCs have been matter of discussion and a large number of articles have been published abo...

journal_title：Journal of cellular biochemistry

authors： Graziano A,d'Aquino R,Tirino V,Desiderio V,Rossi A,Pirozzi G

更新日期：2008-02-01 00:00:00

abstract：:Given its broad effects in endothelium, vascular endothelial growth factor (VEGF) represents the primary rate-limiting step of angiogenesis. Therefore, VEGF targeting therapies were soon developed. Bevacizumab and ranibizumab are two of these therapeutic agents already in clinical use. Bevacizumab was first used for c...

journal_title：Journal of cellular biochemistry

authors： Costa R,Carneiro A,Rocha A,Pirraco A,Falcão M,Vasques L,Soares R

更新日期：2009-12-15 00:00:00

abstract：:The role of circular RNAs (circRNAs) in regulating cartilage homeostasis in osteoarthritis (OA) has been reported. However, the regulatory mechanisms of circRNAs in OA synovium remains basically unidentified. The current study intended to divulge the expression profile of circRNAs in OA synovium and investigate the po...

journal_title：Journal of cellular biochemistry

authors： Xiang S,Li Z,Bian Y,Weng X

更新日期：2019-10-01 00:00:00

abstract：:APC and PTEN are tumor suppressor proteins that bind through their C-termini to the PDZ domain containing-hDlg scaffolding protein. We have found that co-expression of PTEN and hDlg enhanced the negative regulation of the PI3K/Akt pathway by PTEN, indicating the physiologic importance of these interactions. APC and PT...

journal_title：Journal of cellular biochemistry

authors： Sotelo NS,Valiente M,Gil A,Pulido R

更新日期：2012-08-01 00:00:00

abstract：:1alpha,25-dihydroxyvitamin D(3) (1alpha,25(OH)(2)D(3)), the active metabolite of vitamin D, mediates many of its effects through the intranuclear vitamin D receptor (VDR, NR1I1), that belongs to the large superfamily of nuclear receptors. Vitamin D receptor can directly regulate gene expression by binding to vitamin D...

journal_title：Journal of cellular biochemistry

authors： Harant H,Spinner D,Reddy GS,Lindley IJ

更新日期：2000-04-01 00:00:00