Octreotide-induced acute pancreatitis in a patient with acquired immunodeficiency syndrome.

Abstract:

:Unremitting diarrhea is a common problem in patients with AIDS. We have reported the case of such a patient who was treated with the somatostatin analogue octreotide for chronic diarrhea and who had acute pancreatitis as a consequence of this therapy. We postulate that the possible mechanism for the pathogenesis of this pancreatic damage was octreotide-induced prevention of pancreatic exocrine secretion. We believe this acted as a "physiologic gallstone", inducing an attack of acute pancreatitis.

journal_name

South Med J

journal_title

Southern medical journal

authors

Gradon JD,Schulman RH,Chapnick EK,Sepkowitz DV

doi

10.1097/00007611-199111000-00035

subject

Has Abstract

pub_date

1991-11-01 00:00:00

pages

1410-1

issue

11

eissn

0038-4348

issn

1541-8243

journal_volume

84

pub_type

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