Abstract:
:During the last 50 years, it has become evident that atherosclerosis originates in childhood. Although cardiovascular disease (CVD) events are rare in children, autopsy data and imaging studies have documented subclinical disease in association with measurable risk factors during childhood. When present at a young age, risk factors track into adulthood and have been associated with a moderate to high risk of future CVD. As such, the ability to identify this vulnerable population creates the opportunity to prevent the development of risk factors and future CVD events with effective management of genetic and acquired risk factors. In 2011, the National Heart, Lung, and Blood Institute Expert Panel published comprehensive guidelines summarizing the current evidence and providing developmentally appropriate recommendations for screening, treatment, and follow-up of children and adults younger than 21 years at risk for premature CVDs such as myocardial infarction and stroke. In addition to screening individuals with a family history of hypercholesterolemia and/or premature CVD, the Expert Panel recommended universal screening of all children between 9 and 11 years of age and then again between 17 and 21 years of age. Although the recommendation for universal screening, regardless of general health or the presence/absence of risk factors of CVD, is not without controversy, this review serves to create awareness among healthcare providers, elected officials, and the lay public about the burden of CVD, the opportunity for prevention, and the benefits of early and effective therapeutic intervention with lifestyle changes and lipid-lowering medications.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Wilson DP,McNeal C,Blackett Pdoi
10.14423/SMJ.0000000000000219subject
Has Abstractpub_date
2015-01-01 00:00:00pages
7-14issue
1eissn
0038-4348issn
1541-8243pii
SMJ14183journal_volume
108pub_type
杂志文章abstract::After a pilot study had suggested that a drug augmented delayed hypersensitivity, we conducted a control study in which 19 normal volunteers had the same skin test battery applied as in the pilot study, on two occasions one month apart with no intervening treatment. No change was observed in delayed hypersensitivity r...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198609000-00009
更新日期:1986-09-01 00:00:00
abstract::We have discussed the pathology of the diverse, numerous neoplasms associated with the central and peripheral types of von Recklinghausen's disease, as exemplified by two case reports. While overlap can occur between these two major types, characteristically this does not occur. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198008000-00036
更新日期:1980-08-01 00:00:00
abstract::An example of a blind-ending branch of a bifid ureter in a woman presenting with a urinary tract infection is reported. Definition, diagnosis, and treatment of this anomaly are discussed. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197907000-00031
更新日期:1979-07-01 00:00:00
abstract::Swing beds contribute significantly to inpatient rehabilitation and skilled nursing care of the rural elderly, but little information is available in the general clinical literature regarding the types and outcomes of patients admitted to these programs. All swing bed admissions to a small rural hospital for the 1989 ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199212000-00008
更新日期:1992-12-01 00:00:00
abstract::Acute calcareous deposits of the hand and wrist have been infrequently reported. A review of the literature and five recent cases indicate that these painful lesions will respond rapidly to immobilization and medication. Differentiation from infection is important. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198002000-00009
更新日期:1980-02-01 00:00:00
abstract:OBJECTIVES:Current US healthcare delivery systems do not adequately address healthcare demands. Physicians are integral but rarely emphasize prevention as a primary tool to change health outcomes. Home visitation is an effective method for changing health outcomes in some populations. The Florida International Universi...
journal_title:Southern medical journal
pub_type: 杂志文章,随机对照试验
doi:10.1097/SMJ.0000000000000080
更新日期:2014-04-01 00:00:00
abstract::Two cases are presented in which an association between unilateral renal agenesis and multiple skeletal abnormalities is found. The pathologic agents responsible for the URA act similarily on other organ systems, including the skeleton. The skeletal abnormality can be diagnosed easily and promptly and may be an indica...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197601000-00029
更新日期:1976-01-01 00:00:00
abstract::Geographic variations in adverse health outcomes have long been recognized in the United States, with specific focus on the southeastern region of the country. Cerebrovascular disease mortality rates have identified the Southeast as the "stroke belt" for decades, though rates are also high for other hypertension-relat...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199702000-00005
更新日期:1997-02-01 00:00:00
abstract:OBJECTIVE:Older adults who may not complain of balance problems may nevertheless be developing subtle balance problems that may affect future functioning. This study sought to determine whether subtle problems could be predicted by standard balance testing. METHODS:At the geriatric medicine clinic at an academic terti...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000001138
更新日期:2020-09-01 00:00:00
abstract::We report four cases of group A streptococcal vulvovaginitis in prepubertal children. All cases were acute in onset. This illness presents with nonspecific signs and symptoms of labial inflammation. In a suburban community, streptococcal vulvovaginitis in prepubescent girls may be more common then genital infections d...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198204000-00017
更新日期:1982-04-01 00:00:00
abstract::We report the case of a 29-year-old woman who had acute cytomegalovirus hepatitis superimposed on previously unrecognized chronic hepatitis B infection. We then review the diagnostic approach to acute hepatitis and positive hepatitis B surface antigen. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199612000-00017
更新日期:1996-12-01 00:00:00
abstract::This review of the basic purposes and principles of tables is oriented toward their preparation by physician-authors for use in medical manuscripts. The guidelines suggested are consistent with the general format and style current in scientific and medical writing, with emphasis upon the latter. Style and usage do evo...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197612000-00035
更新日期:1976-12-01 00:00:00
abstract::We have presented the case of a 32-year-old man who sustained blunt trauma to the chest in a motor vehicle accident. Plain roentgenograms showed a widened mediastinum and pneumomediastinum, and an esophagogram with water-soluble contrast material showed an esophageal laceration at the T-4 level. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1991-06-01 00:00:00
abstract::We have described an unusual case of tuberculous sacroiliitis associated with adrenal insufficiency, with details of radiologic studies and review of the literature concerning tuberculous sacroiliitis. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198309000-00032
更新日期:1983-09-01 00:00:00
abstract::We report a case of acute appendicitis with perforation associated with retained appendiceal barium. Abnormally retained barium may lead to appendicitis and this should be kept in mind when a barium-filled appendix is seen in an asymptomatic patient. Routine follow-up films on all patients whose appendix fills with ba...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198204000-00037
更新日期:1982-04-01 00:00:00
abstract:BACKGROUND:The Orthopaedic In-Training Examination (OITE) provides an objective way for both the residency program and the resident to monitor progress. METHODS:This longitudinal descriptive study tracks the OITE performance of 16 residents from one orthopaedic surgery residency program over nine years (1997-2005). Do...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e31817c0ba6
更新日期:2008-08-01 00:00:00
abstract:OBJECTIVES:To determine the prevalence of overweight in a cardiac stress testing population, and the percentage of subjects who indicate a history of overweight. METHODS:A total of 251 consecutive subjects presenting for cardiac stress testing in a 450-bed community hospital from June to September 2010 were asked to c...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e31821e9359
更新日期:2011-07-01 00:00:00
abstract::An elderly man with previous tuberculosis exsanguinated from esophageal rupture of an atherosclerotic thoracic aneurysm. Because the patient refused angiography, the source of bleeding was discovered only at autopsy. Selected clinical and pathologic aspects of the case are discussed in relation to the different causes...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197907000-00042
更新日期:1979-07-01 00:00:00
abstract:OBJECTIVES:Concerns regarding lack of privacy, poor patient understanding, and physician discomfort have led to a decline in rounding at the bedside. Our project explored patient perceptions of the implementation and value of bedside rounding. METHODS:This mixed-methods study used semi-structured qualitative interview...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000803
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:Mortality rates for hyperthermia and hypothermia are higher in Alabama than nationally, and Alabama has twice as many hypothermia deaths as hyperthermia deaths. These causes of death have not been studied in the southeastern United States. We describe the epidemiology of heat- and cold-related deaths in Alab...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2000-08-01 00:00:00
abstract::A woman with stable diabetes presented with hypoglycemia and decreased insulin requirement. Further history suggested decreasing pituitary function. Laboratory tests confirmed pituitary deficiencies, associated with her increased insulin sensitivity. It may be helpful to be aware of this syndrome when dealing with dia...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198001000-00033
更新日期:1980-01-01 00:00:00
abstract::A patient with stable non-insulin-dependent diabetes mellitus had five successive cranial nerve palsies, all of which resolved. This syndrome is rarely encountered in patients with diabetes and in otherwise healthy individuals. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198502000-00027
更新日期:1985-02-01 00:00:00
abstract::Three members of a family with Peutz-Jeghers syndrome had intussusception due to intestinal hamartomas. In addition, the grandfather had carcinoma of the jejunum, and the granddaughter had benign ovarian sex cord/stromal tumor causing sexual precocity. Benign and malignant tumors, not often associated with Peutz-Jeghe...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199110000-00011
更新日期:1991-10-01 00:00:00
abstract:OBJECTIVES:This study describes the clinical problems and psychiatric diagnoses of college students who sought services at a student counseling clinic and were subsequently referred for evaluation by a psychiatrist. Several important psychiatric problems present before leaving for college that could mandate the selecti...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000001089
更新日期:2020-05-01 00:00:00
abstract::A 66-year-old woman with a subacute onset of mild dementia and headaches was discovered to have multiple large, hyperdense lesions on cranial CT scan. Biopsy showed poorly differentiated adenocarcinoma with necrosis and dystrophic calcification, which represented an unusual initial manifestation of metastatic breast c...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198602000-00030
更新日期:1986-02-01 00:00:00
abstract::We have reported a case of benign papillary mesothelioma of the peritoneum found incidentally during surgical exploration in a patient with rectal carcinoma. Clinicians and pathologists alike may find it difficult to differentiate this uncommon lesion from metastatic tumors. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198912000-00032
更新日期:1989-12-01 00:00:00
abstract:OBJECTIVES:Guidelines have recommended that risk stratification be performed in patients diagnosed with an acute pulmonary embolism (PE). No study has described the use of risk stratification in routine clinical practice. The purpose of this study was to measure the frequency and impact of risk stratification on treatm...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0000000000000053
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:The effects of chronic diuretic use on serum homocysteine and its metabolic cofactors vitamin B6, vitamin B12, and red blood cell (RBC) folate have not been well studied. METHODS:Blood samples from 17 hypertensive patients receiving long-term diuretic therapy and 17 hypertensive patients not taking diuretic...
journal_title:Southern medical journal
pub_type: 临床试验,杂志文章
doi:10.1097/00007611-199909000-00003
更新日期:1999-09-01 00:00:00
abstract::Most congenital heart anomalies now can be surgically corrected in a neonate or very young infant. Because their hearts are so small, it is advantageous to work in a bloodless and motionless operative field. Deep hypothermia with circulatory arrest provides this setting. Physiologic problems associated with hypothermi...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197605000-00038
更新日期:1976-05-01 00:00:00
abstract::We have described a patient who died of disseminated strongyloidiasis as a result of steroid therapy, despite an extensive diagnostic evaluation in the face of eosinophilia, but before any immunosuppressive therapy. This death might have been prevented by presumptive treatment after work-up but before immunosuppressiv...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198311000-00030
更新日期:1983-11-01 00:00:00