Abstract:
:Sickle cell disease (SCD) is the most common hereditary disorder and affects 30 million people worldwide. Advances in science have improved overall survival in patients with SCD and as such, more patients are reaching reproductive age and are becoming pregnant. SCD in pregnancy leads to multiple complications that put both the mother and fetus at risk, and patients with SCD have six times the mortality during pregnancy as compared with patients without SCD. This review summarizes the maternal and fetal risks of patients with SCD and makes recommendations on how best to care for these patients throughout all stages of pregnancy.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Hathaway ARdoi
10.14423/SMJ.0000000000000514subject
Has Abstractpub_date
2016-09-01 00:00:00pages
554-6issue
9eissn
0038-4348issn
1541-8243pii
SMJ50241journal_volume
109pub_type
杂志文章,评审abstract:BACKGROUND:In this study, the clinical characteristics, survival, and prognostic factors of 200 patients diagnosed as having chronic lymphocytic leukemia (CLL) were analyzed. METHODS:The medical charts of 200 CLL patients registered to our center between 1984 and 2000 were retrospectively evaluated. RESULTS:Of all pa...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.SMJ.0000053674.03385.B7
更新日期:2004-03-01 00:00:00
abstract::Sepsis due to Pseudomonas aeruginosa continues to be an important source of morbidity and mortality in hospitalized patients. Early recognition of this condition is of paramount importance in choosing specific therapy at the earliest possible moment. We present three cases in which P aeruginosa bacteremia was manifest...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199402000-00017
更新日期:1994-02-01 00:00:00
abstract:OBJECTIVES:Cystic fibrosis (CF) is associated with vitamin D deficiency, which can lead to adverse effects including recurrent pulmonary infections and osteoporosis. We longitudinally investigated calcifediol or 25-hydroxyvitamin D (25(OH)D) levels for our pediatric patients with CF based on the time of year as well as...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000254
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:This study was done to determine the safety, efficacy, dosing requirements, and spontaneous recovery profiles of prolonged infusions of rocuronium bromide in the critically ill. METHODS:This multicenter, prospective, nonrandomized, open label trial enrolled 32 patients at two university-based medical center...
journal_title:Southern medical journal
pub_type: 临床试验,杂志文章,多中心研究
doi:
更新日期:2001-01-01 00:00:00
abstract::To our knowledge, this is the first known case of a patient with leptospirosis and very elevated CSF, which caused hydrocephalus. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181a0ae80
更新日期:2009-05-01 00:00:00
abstract::We have described a case of hypophosphatasia with a mild progressive course. This condition and its familial propensity may be more prevalent than recognized. Thus, family members of a patient with hypophosphatasia should be screened for this disorder. Enthusiastic pharmacologic, hormonal, and/or dietary supplemental ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198312000-00030
更新日期:1983-12-01 00:00:00
abstract::An unusual volar and radial perilunate transscaphoid fracture dislocation is reported. Treatment of perilunate transscaphoid fracture dislocations by closed reduction often produces a poor result. Early open reduction may be followed by a good result, but if open reduction is impossible, proximal row carpectomy is adv...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197507000-00025
更新日期:1975-07-01 00:00:00
abstract::Reviewed are 200 cases in which endolaryngeal suspension microsurgical procedures were done using intravenous anesthesia and Venturi insufflation oxygenation. Patients included 177 adults and 23 children, ranging in age from 20 months to 88 years. No significant complications were observed. The technic allowed the glo...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197607000-00003
更新日期:1976-07-01 00:00:00
abstract:OBJECTIVE:Few tests of functional motor behavior are useful for rapidly screening people for lower extremity peripheral neuropathy. The goal of this study was to improve the widely used tandem walking (TW) test. METHODS:We tested "normal" (control) adult and ambulatory patients with peripheral neuropathy (PN) with the...
journal_title:Southern medical journal
pub_type: 临床试验,杂志文章
doi:10.1097/SMJ.0000000000000009
更新日期:2013-10-01 00:00:00
abstract::Dietary advice based on saturated versus unsaturated fatty acids for the purpose of controlling the plasma cholesterol level has for many years plagued the American public with unpalatable diets that are difficult to adhere to. Stearic acid, an 18-carbon saturated fatty acid, does not share the hypercholesterolemic ef...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199201000-00007
更新日期:1992-01-01 00:00:00
abstract::Sickle cell trait is present in about 8% of black Americans, and clinically significant sickling disorders are common in this population. These disorders can be accurately defined by combinations of quantitative hemoglobin electrophoresis at alkaline pH, citrate agar electrophoresis, solubility tests for sickle hemogl...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197804000-00021
更新日期:1978-04-01 00:00:00
abstract::We have described a young man who had acute myocardial infarction after his first use of cocaine. This case demonstrates that potentially lethal myocardial infarctions may be associated with such initial "experimentation" with cocaine even in relatively small doses. Cocaine intoxication should be considered in young p...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198707000-00035
更新日期:1987-07-01 00:00:00
abstract::In a prospective study of the etiology of pneumonia in patients hospitalized at a university hospital, all respiratory secretions were tested for routine pathogens as well as Legionella. A diagnosis was established in 60 of 87 patients studied. Of the 37 nosocomial infections, six were caused by L micdadei. Gram-negat...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198604000-00007
更新日期:1986-04-01 00:00:00
abstract::Overall physical fitness has become increasingly popular in the 1990s, especially in the geriatric community. More runners, bikers, swimmers, and aerobic advocates over the age of 55 are requiring medical attention for foot complaints, as the feet are a necessary tool for almost any athletic activity. This paper discu...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1994-05-01 00:00:00
abstract::A case of SLE with the unique association of gastric polyps and vasculitis is reported. Gastrointestinal symptoms, surgical indications, and complications of SLE with gastrointestinal involvement are reviewed. The unusual patterns of ileus or lupus peritonitis secondary to mesenteric vasculitis must be differentiated ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1976-04-01 00:00:00
abstract::Aminoglycosides have been reported to cause tetany by inducing renal wasting of magnesium and secondary hypocalcemia. A 9-year-old girl with AIDS was brought to the emergency department because of tetany. She had just finished a 3-week course of intravenous tobramycin for bronchiectasis and had an elevated serum tobra...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199611000-00019
更新日期:1996-11-01 00:00:00
abstract:BACKGROUND:Our objective was to improve breastfeeding initiation rates at an urban medical center. METHODS:A breastfeeding educational program for health care providers was developed and implemented in 1995. The outcome variable of interest was the change in breastfeeding initiation rate during 2 periods, 1993-1994 an...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2002-08-01 00:00:00
abstract::We have reported a case of suppurative pylephlebitis in an elderly, debilitated patient. The infection was caused by toothpick perforation of and migration from the gastrointestinal tract. The patient had risk factors for foreign body ingestion, including poor dentition, aphasia caused by a previous cerebrovascular ac...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198803000-00034
更新日期:1988-03-01 00:00:00
abstract:BACKGROUND:The decision to place a percutaneous feeding tube (PFT) in patients who are at the end of life is multidimensional and often complicated. We assessed the effect of physician education and counseling for patients and their surrogates on inpatient nonsurgical (endoscopic and radiologic) PFT placement rates, in...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181c9800f
更新日期:2010-02-01 00:00:00
abstract::Survival of infants with necrotizing enterocolitis may be complicated by intestinal stricture(s) as a result of healing of ischemic segments of bowel. An asymptomatic cecal stenosis not visible on barium enema was identified at operation for reestablishment of intestinal continuity. Infants recovering from acute necro...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197912000-00039
更新日期:1979-12-01 00:00:00
abstract:BACKGROUND:Use of mucolytic agents that result in reduced mucous viscosity of the gastric mucous has been suggested to have an additive effect in curing Helicobacter pylori infection. METHODS:Seventy Hpylori-positive patients were given either eradication treatment consisting of 500 mg clarithromycin bid and 30 mg lan...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.smj.0000182486.39913.da
更新日期:2005-11-01 00:00:00
abstract::Presented in a case in which calcification of the adrenal gland was roentgenographically evident on the first day of life. The earliest previously reported case of adrenal calcification was at 8 days of age and was attributed to an intrapartum hemorrhage. It is proposed that an intrauterine third trimester insult was ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197903000-00045
更新日期:1979-03-01 00:00:00
abstract::Acute gastroduodenal erosions and ulcerations, often with life-threatening gastrointestinal hemorrhage, contribute to high mortality in critically ill patients. Hypersecretion of gastric acid to some degree seems to be necessary. Antacids and recently cimetidine, a histamine H2-receptor antagonist, have been used for ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198004000-00007
更新日期:1980-04-01 00:00:00
abstract::Inhalation abuse of volatile solvents, previously known generically as "glue sniffing," is typically pursued by adolescents. A wide range of legal, easily obtained products containing volatile substances are available for abuse. We report two illustrative cases of fatal volatile substance abuse: gasoline sniffing in a...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1996-09-01 00:00:00
abstract::Three neonates with gram-negative bacillary meningitis were treated with moxalactam after therapy with ampicillin plus aminoglycoside, trimethoprim-sulfamethoxazole, or chloramphenicol failed to sterilize the CSF. Clinical improvement and CSF sterility occurred after therapy with moxalactam was initiated. Moxalactam c...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198205000-00040
更新日期:1982-05-01 00:00:00
abstract::Sleep loss impairs ventilatory responsiveness to hypercapnia and hypoxia, and also interferes with performance on spirometry. To test the hypothesis that the decline in hypercapnic drive due to sleep loss is mediated by endorphin production, we measured loaded and unloaded CO2 response after injection of placebo and n...
journal_title:Southern medical journal
pub_type: 临床试验,杂志文章
doi:10.1097/00007611-198701000-00004
更新日期:1987-01-01 00:00:00
abstract::Of 24 elderly patients with Streptococcus pneumoniae pneumonia confirmed by transtracheal aspiration, six had concomitant infection with gram-negative aerobic bacilli. All six patients were elderly men with underlying cardiopulmonary disease. Three had had recent prior episodes of gram-negative pneumonia and four had ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198102000-00004
更新日期:1981-02-01 00:00:00
abstract::The scapulocostal syndrome is an often encountered yet infrequently diagnosed cause of back and/or shoulder pain. Results of examination and treatment in the three cases described point out the necessary differential diagnosis to effectively screen these groups of patients from among those with more complex diseases. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198004000-00010
更新日期:1980-04-01 00:00:00
abstract::Primary malignant melanoma of the oral cavity is uncommon. Four cases are presented. The average age is in the sixth decade. Early diagnosis is difficult and prognosis is generally poor. Efforts toward earlier detection and treatment are recommended. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198002000-00045
更新日期:1980-02-01 00:00:00
abstract::We reviewed our experience with thyroid sonography of 60 patients with nonfunctioning (cold) solitary thyroid nodules proven by iodine 123 scan. Twenty-two patients had surgery; the remaining 38 had thyroid scan and ultrasound only. In the first group, the echograms did not demonstrate the surgically proven nodules in...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198409000-00024
更新日期:1984-09-01 00:00:00