Laboratory Diagnosis of sickling hemoglobinopathies.

Abstract:

:Sickle cell trait is present in about 8% of black Americans, and clinically significant sickling disorders are common in this population. These disorders can be accurately defined by combinations of quantitative hemoglobin electrophoresis at alkaline pH, citrate agar electrophoresis, solubility tests for sickle hemoglobin, fetal hemoglobin measurements, blood counts, erythrocyte indices and family studies. Unusual types of sickling hemoglobinopathies may require more extensive, specialized study. An unquestioned diagnosis should be prerequisite for any subsequent genetic counseling.

journal_name

South Med J

journal_title

Southern medical journal

authors

Steinberg MH,Adams JG 3rd

doi

10.1097/00007611-197804000-00021

subject

Has Abstract

pub_date

1978-04-01 00:00:00

pages

413-6

issue

4

eissn

0038-4348

issn

1541-8243

journal_volume

71

pub_type

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