Severe thrombocytopenia due to hypersplenism successfully treated with partial splenic embolization in preoperative management.

Abstract:

:Hypersplenism is a known complication of portal hypertension secondary to cirrhosis of the liver. Although thrombocytopenia secondary to hypersplenism does not cause clinically significant hemostatic defect, it may need to be addressed in selective circumstances, such as preoperative preparation for a surgery. This report describes a 30-year-old male with a history of cirrhosis of the liver and hypersplenism who had a recurrence of craniopharyngioma. A platelet count of 40 x 10(9)/L limited his treatment options. A stereotactic injection of radioactive P32 into the tumor was planned but was thought not to be feasible because of the thrombocytopenia. The thrombocytopenia responded favorably to partial splenic embolization, and the patient underwent successful stereotactic injection of radioactive P32 into the tumor.

journal_name

South Med J

journal_title

Southern medical journal

authors

Pinto AG,Namyslowski J,Pandya P

doi

10.1097/01.SMJ.0000157558.62378.0B

subject

Has Abstract

pub_date

2005-04-01 00:00:00

pages

481-3

issue

4

eissn

0038-4348

issn

1541-8243

journal_volume

98

pub_type

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