Medical complications of hemophilia.

Abstract:

:The modern, comprehensive care of patients with hemophilia requires an awareness that complications other than those caused by acute hemorrhage can occur. The use of newer, more potent plasma concentrates has been accompanied by an increased incidence of liver disease in transfusion-requiring hemophiliacs. The progression to chronic active hepatitis and cirrhosis are particularly ominous developments in these patients. There is also a high incidence of urinary tract abnormalities in hemophiliacs, though the long-term consequences of these abnormalities are unknown. Furthermore, it must be remembered that urinary tract disorders unrelated to hemorrhage, such as nephrolithiasis, tumors, and nephritis, can occur in patients with hemophilia and may be mistaken for hemorrhage. Finally, hypertension occurs more frequently in patients with hemophilia than in the general population and may in part contribute to the occurrence of bleeding within the central nervous system. Methods for evaluating and treating these various disorders are discussed. Greater awareness of these potentially treatable medical complications will improve further the quality of care in hemophilia.

journal_name

South Med J

journal_title

Southern medical journal

authors

White GC 2nd,Blatt PM,McMillan CW,Webster WP,Lesesne HR,Roberts HR

doi

10.1097/00007611-198002000-00011

subject

Has Abstract

pub_date

1980-02-01 00:00:00

pages

155-60

issue

2

eissn

0038-4348

issn

1541-8243

journal_volume

73

pub_type

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