Abstract:
BACKGROUND:Increasing numbers of the adult population are using alternative or complementary health resources in the treatment of chronic medical conditions. Systemic hypertension affects more than 50 million adults and is one of the most common risk factors for cardiovascular morbidity and mortality. This study evaluates the antihypertensive effectiveness of oral coenzyme Q10 (CoQ), an over-the-counter nutritional supplement, in a cohort of 46 men and 37 women with isolated systolic hypertension. METHODS:We conducted a 12-week randomized, double-blind, placebo-controlled trial with twice daily administration of 60 mg of oral CoQ and determination of plasma CoQ levels before and after the 12 weeks of treatment. RESULTS:The mean reduction in systolic blood pressure of the CoQ-treated group was 17.8 +/- 7.3 mm Hg (mean +/- SEM). None of the patients exhibited orthostatic blood pressure changes. CONCLUSIONS:Our results suggest CoQ may be safely offered to hypertensive patients as an alternative treatment option.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Burke BE,Neuenschwander R,Olson RDdoi
10.1097/00007611-200111000-00015subject
Has Abstractpub_date
2001-11-01 00:00:00pages
1112-7issue
11eissn
0038-4348issn
1541-8243journal_volume
94pub_type
临床试验,杂志文章,随机对照试验abstract::Endorphins and narcotics have been implicated in the exacerbation of neurologic deficits after stroke. To test the theory that narcotic antagonists might offer an improvement in neurologic sequelae following stroke, we administered various doses of naloxone intraperitoneally to 50 adult gerbils 45 minutes after caroti...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198905000-00005
更新日期:1989-05-01 00:00:00
abstract::Appropriate use of antibiotics is enhanced by the effective application of data on antimicrobial susceptibility. A number of methods are currently available for routine determination of susceptibilities, including agar dilution, broth dilution, agar diffusion, and several semiautomated methods. If susceptibility testi...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1977-10-01 00:00:00
abstract::We compared personal and sexual behavior of a group of 32 young adult women who had a culture proven urinary tract infection (UTI) and a group of 28 women who had no urinary symptoms. All women were sexually active, and the two groups were similar for age, race, marital status, history of previous pregnancy, and use o...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198106000-00018
更新日期:1981-06-01 00:00:00
abstract::Overall physical fitness has become increasingly popular in the 1990s, especially in the geriatric community. More runners, bikers, swimmers, and aerobic advocates over the age of 55 are requiring medical attention for foot complaints, as the feet are a necessary tool for almost any athletic activity. This paper discu...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1994-05-01 00:00:00
abstract::An example of a blind-ending branch of a bifid ureter in a woman presenting with a urinary tract infection is reported. Definition, diagnosis, and treatment of this anomaly are discussed. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197907000-00031
更新日期:1979-07-01 00:00:00
abstract::We observed a 30-year-old woman in whom a large mass in the right lower quadrant and bilaterally enlarged cystic kidneys with markedly distorted collecting systems by excretory urography suggested a diagnosis of polycystic renal disease (PRD); but the linear and cystic dilatation of collecting tubules, many of which c...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198407000-00028
更新日期:1984-07-01 00:00:00
abstract:BACKGROUND:One key component of human rabies prevention is the use of postexposure prophylaxis (PEP). No information is routinely available to evaluate the appropriateness of this intervention. METHODS:A survey queried county health departments regarding rabies PEP administered during July through September in 1997 an...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2002-02-01 00:00:00
abstract::We have reported a case of suppurative pylephlebitis in an elderly, debilitated patient. The infection was caused by toothpick perforation of and migration from the gastrointestinal tract. The patient had risk factors for foreign body ingestion, including poor dentition, aphasia caused by a previous cerebrovascular ac...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198803000-00034
更新日期:1988-03-01 00:00:00
abstract::A 29-year-old previously healthy man had a Pseudomonas aeruginosa pneumonia and bacteremia. Early recognition of the organism and institution of appropriate antibiotic therapy led to rapid clinical response and recovery. Although Pseudomonas is rarely the cause of pneumonia in a healthy host, it should be considered i...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198302000-00033
更新日期:1983-02-01 00:00:00
abstract::A 36-year-old man was found to have severe pulmonary hypertension and a right-to-left shunt secondary to a patent ductus arteriosus. Attempt at surgical closure was unsuccessful. The patient was followed up for 21 years, and his only significant medical problem is leg weakness to moderate exertion. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198005000-00036
更新日期:1980-05-01 00:00:00
abstract::Pain is a tax levied on man for the privilege of life upon this planet. Some are taxed lightly and others are taxed heavily, but all are taxed. To relieve this stress, from time immemorial man has taken analgesics. In modern times, if home medication fails, professional consultation is available. The important questio...
journal_title:Southern medical journal
pub_type: 历史文章,杂志文章
doi:
更新日期:1980-12-01 00:00:00
abstract::Prognosis of angiosarcoma, the most common primary malignant cardiac tumor, is very poor. An early detection and treatment may extend survival beyond one year. Newer imaging modalities, including magnetic resonance imaging (MRI), play an important role in the evaluation of cardiac masses. The case of a man admitted to...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181ecfb64
更新日期:2010-10-01 00:00:00
abstract::The percutaneous subclavian vein hemodialysis catheter, which is widely used for vascular access in patients with renal failure, can give rise to several complications. Asymptomatic stenosis or occlusion of the subclavian vein due to these catheters can lead to painful arm edema if further dialysis accesses are constr...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198803000-00004
更新日期:1988-03-01 00:00:00
abstract::Review of 185 consecutive Muller total hip arthroplasties five to nine years after operation showed that 14 patients had died and that three deaths were directly related to the surgery. Of these, 37 patients (54 hips) could not be located and were excluded. Another patient, nonambulatory for an unrelated cause, was al...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1982-08-01 00:00:00
abstract::Haemophilus influenzae endocarditis on a prosthetic valve has previously been reported only once. Routine physical and laboratory evaluation does not distinguish endocarditis from this organism from other causes of endocarditis. Our patient with prosthetic mitral valve endocarditis was successfully treated with antibi...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198506000-00041
更新日期:1985-06-01 00:00:00
abstract::We reviewed the records of 100 consecutive patients who had gastroscopy. All endoscopic work was done by our four-man surgical group. Roentgenographic and endoscopic diagnoses are compared with reference to degree of accuracy. The expanded uses of gastroscopy in surgical practice are illustrated and a plea is made for...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197802000-00012
更新日期:1978-02-01 00:00:00
abstract::During the last 50 years, it has become evident that atherosclerosis originates in childhood. Although cardiovascular disease (CVD) events are rare in children, autopsy data and imaging studies have documented subclinical disease in association with measurable risk factors during childhood. When present at a young age...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000219
更新日期:2015-01-01 00:00:00
abstract::This case report describes an accidental ingestion of a gold dental inlay prosthesis that became lodged in the appendix. A nonsurgical approach was pursued because this blunt foreign body posed a minimal perforation risk. A second opinion for an elective appendectomy was chosen by the patient until a preoperative abdo...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199807000-00012
更新日期:1998-07-01 00:00:00
abstract::Penile cancer is very rare in North America and Europe, as compared with the rest of the world. Squamous cell carcinoma (SCC) accounts for more than 95% of the cancer type. Paraneoplastic syndrome (PNS), a clinical syndrome of nonmetastatic systemic effects that occurs in patients with malignant disease, is often asso...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181d7b802
更新日期:2010-05-01 00:00:00
abstract::A three-year prospective study during the entire course of preventive therapy with isoniazid (INH) for recently infected hospital employees was undertaken to evaluate the risk of developing INH-related hepatic injury. Results of clinical and laboratory tests at 1, 2, 6, and 12 months were correlated to ascertain the s...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197702000-00009
更新日期:1977-02-01 00:00:00
abstract::Using a phylogenic classification of the spine, one can identify precisely the numerical location of any vertebra or disc, including vertebrae with junctional anomalies at transitional zones. Such precision permitted comparisons of myelographic reports of sites of disc disease with the actual levels of extradural defo...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197909000-00017
更新日期:1979-09-01 00:00:00
abstract::Blastomyces dermatitidis, a dimorphic broad-based budding yeast endemic to the Mississippi River Valley region, is responsible for morbidity in humans via inhalation and dissemination. The response of acute lung injury, which produces an illness with serious morbidity and an approximately 50% mortality, uncommonly occ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199809000-00012
更新日期:1998-09-01 00:00:00
abstract::Investigation into the severity of hemolytic disease due to Rh isoimmunization may be complicated by concurrent amniotic fluid contamination with bile. We have presented a case in which a prenatal sonogram showed evidence of fetal intestinal obstruction, which was subsequently confirmed postpartum by exploratory lapar...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1990-02-01 00:00:00
abstract::A patient who presented with recurrent syncopal episodes was discovered to have a right-sided heart mass, which was revealed as an embolus in transit resulting in a lethal pulmonary embolic event. The initial focus of etiology on tumor rather than thrombus was misleading. A higher index of suspicion of thrombus in rig...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.SMJ.0000056644.09367.F3
更新日期:2003-11-01 00:00:00
abstract::Mesenteric lipodystrophy (ML) is a rare condition characterized by a nonspecific inflammatory process that involves the root of the mesentery in a lipoma-like lesion. Presenting features of ML include abdominal pain, weight loss, nausea, vomiting, diarrhea, and constipation. This case illustrates that ML should be inc...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199905000-00013
更新日期:1999-05-01 00:00:00
abstract::A retrospective review of all admissions to the University of Kentucky Medical Center from 1977 to 1987 revealed six persons in whom splenic vein thrombosis could be documented. The patients had either upper gastrointestinal bleeding from gastroesophageal varices or abdominal pain. Pancreatic disease was present in fi...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199004000-00014
更新日期:1990-04-01 00:00:00
abstract:OBJECTIVES:This study describes the clinical problems and psychiatric diagnoses of college students who sought services at a student counseling clinic and were subsequently referred for evaluation by a psychiatrist. Several important psychiatric problems present before leaving for college that could mandate the selecti...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000001089
更新日期:2020-05-01 00:00:00
abstract::Several treatment regimens of trimethoprim-sulfamethoxazole (TMP-SMZ) were compared to the USPHS-recommended schedules for treatment of uncomplicated gonorrhea with ampicillin plus probenecid, tetracycline, or aqueous procaine penicillin G in both men and women. TMP-SMZ, six tablets as a single oral dose daily for 3 d...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197509000-00020
更新日期:1975-09-01 00:00:00
abstract::Phantom sensation and phantom limb pain are two recognized sequelae of limb amputation. In most previous surveys, amputations were done for arteriosclerotic or trauma related conditions. We studied 25 patients who had lower extremity amputation for neoplasia. In studying the features of pain before and after amputatio...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198501000-00009
更新日期:1985-01-01 00:00:00
abstract::We present a rare case of placenta increta, confirmed postoperatively by pathologic analysis, occurring before 20 weeks' gestation in a blighted ovum. Hysterectomy was necessary for control of hemorrhage. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199605000-00023
更新日期:1996-05-01 00:00:00