The 5 Ps of acute ischemic stroke treatment: parenchyma, pipes, perfusion, penumbra, and prevention of complications.

Abstract:

:Stroke is a treatable disease. Despite the therapeutic nihilism of the past, the advent of thrombolysis has changed the way stroke is approached. Acute ischemic stroke is a challenging and heterogeneous disease. Treatment needs to be based on an understanding of the underlying pathophysiology of ischemia. Interventions are designed to improve neuronal salvage and outcome. The underlying tenets of stroke therapy focus on the brain parenchyma, arterial flow (pipes), perfusion, the ischemic milieu or penumbra, and prevention of complications. This article focuses on the practical issues of ischemic stroke care, with a brief review of supporting literature.

journal_name

South Med J

journal_title

Southern medical journal

authors

Felberg RA,Naidech AM

doi

10.1097/01.SMJ.0000063573.56033.A6

subject

Has Abstract

pub_date

2003-04-01 00:00:00

pages

336-42

issue

4

eissn

0038-4348

issn

1541-8243

journal_volume

96

pub_type

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