Abstract:
:Psoriasis treatments range from topical treatments and phototherapy to oral systemic medications and injections. Despite good control of the disease when applying appropriate treatments (according to disease severity, insurance parameters, patient preference, and patients' ability to adhere), continued advancements will allow even better symptomatic control, reduced adverse effects, and patient satisfaction. This review aims to assess traditional and new psoriasis treatments and how to apply them in clinical practice. A literature review on psoriasis treatments and clinical applications was performed using PubMed. Mild-to-moderate psoriasis treatments include topicals, localized phototherapy, and newer therapies combining two types of topicals, phototherapy with topicals, and easy-to-use foam and spray vehicles. Moderate-to-severe psoriasis therapies include monotherapy or various combinations of generalized phototherapy, oral treatments, and biologic agents, with new oral and biologic agents on the horizon. Dermatologists and primary care providers share roles in screening for associated comorbidities (including cardiovascular disorders, chronic kidney disease, Crohn disease, dyslipidemia, diabetes mellitus/insulin resistance, depression, metabolic syndrome, obesity, and psoriatic arthritis), managing patients' treatments, and reevaluating treatment needs as new therapies are approved. Continued advancements in psoriasis treatment and improvement in coordinated care will allow better overall care of patients with psoriasis.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Smith J,Cline A,Feldman SRdoi
10.14423/SMJ.0000000000000596subject
Has Abstractpub_date
2017-01-01 00:00:00pages
65-75issue
1eissn
0038-4348issn
1541-8243pii
SMJ50324journal_volume
110pub_type
杂志文章,评审abstract::When patient records are to be auditied in a program designed to assess the quality of medical care rendered, careful consideration must be given to the cost of the system implemented. Structured data collection and a defined treatment plan are advantageous in facilitating the use of nonphysicians for the majority of ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197610000-00022
更新日期:1976-10-01 00:00:00
abstract::Multiple sclerosis (MS) is among the most crippling diseases of the nervous system in young adults, and diagnosis can be difficult. It is true that MS can exist without magnetic resonance imaging or cerebrospinal fluid abnormalities, but whenever there are an atypical clinical pattern and no confirmatory laboratory te...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199603000-00008
更新日期:1996-03-01 00:00:00
abstract::Public outcry regarding unsafe interhospital patient transfers led to the passage of the COBRA Law of 1985. Since its implementation in 1986, the law has been sharply criticized for its sporadic enforcement, narrow focus, and lack of care provisions for the poor. We reviewed retrospectively the charts of all emergency...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199311000-00004
更新日期:1993-11-01 00:00:00
abstract:BACKGROUND:The management of acute pain is an aspect of hospital-based practice that has been neglected. Control of pain is important for ethical reasons, for compliance with new guidelines and standards, and for optimizing patient satisfaction and outcomes. METHODS:Be review the rationale for establishing priority to...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199905000-00003
更新日期:1999-05-01 00:00:00
abstract::Blastomyces dermatitidis, a dimorphic broad-based budding yeast endemic to the Mississippi River Valley region, is responsible for morbidity in humans via inhalation and dissemination. The response of acute lung injury, which produces an illness with serious morbidity and an approximately 50% mortality, uncommonly occ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199809000-00012
更新日期:1998-09-01 00:00:00
abstract::Aspergilloma is a common complication of cystic lung disease; it is widely considered to be a saprophytic colonization and local or disseminated invasion is unusual. We describe a patient with stage IV sarcoidosis and bilateral aspergillomas in whom locally invasive disease led to spinal cord compression. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198405000-00028
更新日期:1984-05-01 00:00:00
abstract::In 32 patients with the onset of myasthenia gravis after age 50, myasthenic crisis occurred in 53% and persisted for a mean of 33 days (range six to 84 days). Three of the patients had a second crisis. Precipitating factors were found in 60% of the episodes. Treatment of 20 episodes of crisis resulted in excellent rec...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198510000-00017
更新日期:1985-10-01 00:00:00
abstract::We retrospectively analyzed experience with total gastrectomy (TG) for gastric carcinoma in 23 patients. The TNM stage was I in one patient, II in one patient, III in eight patients, and IV in 13. Linitis plastica was found in ten patients. The operation was considered curative in only eight patients (35%). There were...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198908000-00011
更新日期:1989-08-01 00:00:00
abstract:BACKGROUND:Nontubercular mycobacteria (NTM) are increasingly recognized to cause lung disease in immunocompetent patients. We studied the occurrence of pulmonary infection due to NTM in immunocompetent men. METHODS:We retrospectively analyzed all sputum mycobacterial cultures at our institution over a 5-year period. C...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2001-07-01 00:00:00
abstract::Skin and soft tissue necrosis is an uncommon but increasingly recognized complication of coumarin anticoagulant therapy. A patient is described with extensive involvement of all four extremities and the nose, requiring amputation of three extremities. The characteristic clinical features of the disorder are reviewed, ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198011000-00015
更新日期:1980-11-01 00:00:00
abstract::Coronary heart disease (CHD) is the leading cause of morbidity and mortality in patients more than 65 years old. Within this population, elevated cholesterol levels are prevalent and associated with increased risk of CHD. Despite increasing emphasis on lipid-lowering treatment in the elderly population, questions rema...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:
更新日期:2002-11-01 00:00:00
abstract:OBJECTIVE:To assess the current use of β-blockers in patients with compelling indications for use, following the acute exacerbation of chronic obstructive pulmonary disease (COPD). METHODS:We performed a multicenter retrospective observational study using data from all of the patients admitted to five institutions for...
journal_title:Southern medical journal
pub_type: 杂志文章,多中心研究
doi:10.14423/SMJ.0000000000001038
更新日期:2019-11-01 00:00:00
abstract::Pregnancy is an unusual occurrence in women with ESRD. We report a successful pregnancy in a patient with ESRD who was receiving hemodialysis; she gave birth to a healthy female infant at 34 weeks' gestational age. We discuss possible physiologic causes of gonadal dysfunction in patients with ESRD. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199102000-00033
更新日期:1991-02-01 00:00:00
abstract::Asthma is a chronic inflammatory disease in which the genetic predisposition to allergic disease is the strongest identifiable predisposing factor. (1) Optimal outpatient treatment of asthma includes identifying and minimizing exposure to asthma triggers, whether they Me allergens or irritants. When these triggers are...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:
更新日期:2002-07-01 00:00:00
abstract::Brown recluse spider bites are usually self-limited skin lesions that infrequently progress to bullae, ulceration, and scarring. We treated a patient with a documented brown recluse bite who had recurring lesions resembling pyoderma gangrenosum (PG) that persisted for months. Three other patients referred to Vanderbil...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198503000-00012
更新日期:1985-03-01 00:00:00
abstract::Clinicians should be on the alert for the possibility of underlying thyrotoxicosis in patients having an affective disturbance. An initial detailed medical history and complete physical examination is essential even in severely agitated, threatening patients. The danger of inappropriate diagnosis and treatment of thes...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198811000-00032
更新日期:1988-11-01 00:00:00
abstract::Coronary artery spasm can occur in the presence of excessive alpha-adrenergic tone. A decrease in protective coronary vasodilator substance and enhanced alpha-adrenergic responsiveness, which occurs in the setting of hypothroidism and beta blockade, predisposes to coronary artery spasm. The case presented supports the...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197907000-00004
更新日期:1979-07-01 00:00:00
abstract::Unicompartmental replacement using the Marmor prosthesis was done in 40 knees (37 patients) with medial compartment gonarthrosis. Of the 27 available for follow-up, results were considered excellent in 18 cases and good in seven, while two cases were considered failures. Meticulous removal of osteophytes by intercondy...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197906000-00013
更新日期:1979-06-01 00:00:00
abstract::We studied 56 patients with primary gastrointestinal lymphoma to determine the manifestations, diagnostic and treatment methods, and patient outcomes. We identified 27 cases of primary gastric lymphoma and 29 cases of lymphoma involving the remainder of the gastrointestinal tract. Initial symptoms were nonspecific and...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198508000-00004
更新日期:1985-08-01 00:00:00
abstract:OBJECTIVE:We sought to determine predictors of coronary events (cardiac death, acute myocardial infarction, and urgent revascularization) within 30 days after admission. METHODS:We prospectively collected data on 400 patients admitted through our emergency room for unstable angina and acute coronary syndromes. Patient...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.SMJ.0000053481.49309.58
更新日期:2003-11-01 00:00:00
abstract::The clinical, pathologic, and roentgenographic features of macrodactylia fibrolipomatosis described are based on 40 cases from the literature and five cases seen by the authors. This condition previously has been described as macrodactyly, megalodactyly, macrodystrophia lipomatosa, dactylomegaly, and local gigantism. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197612000-00015
更新日期:1976-12-01 00:00:00
abstract::Two new cases of Menetrier's disease in children are reported. The ten cases of this protein-losing gastropathy previously reported in the literature are reviewed. Clinical presentations, laboratory findings, possible causes, and comparison with the adult form of Menetrier's disease are discussed. Menetrier's disease ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197901000-00011
更新日期:1979-01-01 00:00:00
abstract::Most of the surgical procedures proposed for the treatment of fecal incontinence associated with prolapse are associated with considerable morbidity and mortality. We used a modified Thiersch procedure with a Silastic mesh implant (Dow-Corning 501-3) on a series of 12 patients over a period of 2 1/2 years. Nine patien...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198603000-00012
更新日期:1986-03-01 00:00:00
abstract::Chronic metformin use results in vitamin B12 deficiency in 30% of patients. Exhaustion of vitamin B12 stores usually occurs after twelve to fifteen years of absolute vitamin B12 deficiency. Metformin has been available in the United States for approximately fifteen years. Vitamin B12 deficiency, which may present with...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181ce0e4d
更新日期:2010-03-01 00:00:00
abstract::In 1954 I described a case of chronic fluoride poisoning from artificially fluoridated water, in which the patient exhibited a multisymptomatic clinical picture without noticeable skeletal changes. Subsequently, others and I have confirmed this "nonskeletal phase" of the disease from fluoride in water and in air (in w...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1980-03-01 00:00:00
abstract:OBJECTIVES:To evaluate the real-world use of various weight loss techniques and to compare the effectiveness of nontraditional methods with diet and exercise in helping nongeriatric adults lose weight. METHODS:A cross-sectional analysis of the 2005-2010 National Health and Nutrition Examination Survey was performed. A...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000130
更新日期:2014-07-01 00:00:00
abstract::Meropenem is a new carbapenem antibiotic shown to resist degradation by renal dehydropeptidase I. In a multicenter, open-label, prospective trial, we compared the efficacy and safety of meropenem with imipenem/cilastatin in patients with skin and soft tissue infections. Patients received either 500 mg of meropenem eve...
journal_title:Southern medical journal
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1097/00007611-199504000-00003
更新日期:1995-04-01 00:00:00
abstract::We describe the case of a patient with acquired immunodeficiency syndrome (AIDS) who had a CD4 cell count of 60/microL, bilateral hilar adenopathy, and hypercalcemia. Transbronchial biopsy showed T-cell anaplastic large cell lymphoma. Serology was negative for human T-cell leukemia virus-I (HTLV-I). This appears to be...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2000-09-01 00:00:00
abstract::A 30-year-old man had endocarditis and hip arthritis associated with the recently recognized fungus, Scedosporium inflatum. Inhibition, and possibly cure, of endocarditis occurred with medical therapy alone. Data from in vitro susceptibility testing did not predict clinical response. This case also illustrates the nee...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199008000-00025
更新日期:1990-08-01 00:00:00
abstract::Pregnancy in patients who have non-Hodgkin's lymphoma is unusual. We have reported a case of diffuse, poorly differentiated lymphocytic lymphoma, stage IIIa, in a patient whose disease went into remission after she received six courses of CHOP therapy (cyclophosphamide, doxorubicin, vincristine, and prednisolone). She...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198510000-00032
更新日期:1985-10-01 00:00:00