Extensive tissue necrosis associated with warfarin sodium therapy.

Abstract:

:Skin and soft tissue necrosis is an uncommon but increasingly recognized complication of coumarin anticoagulant therapy. A patient is described with extensive involvement of all four extremities and the nose, requiring amputation of three extremities. The characteristic clinical features of the disorder are reviewed, with a discussion of the pathology, pathogenesis, and possible treatment modalities.

journal_name

South Med J

journal_title

Southern medical journal

authors

Scandling J,Walker BK

doi

10.1097/00007611-198011000-00015

subject

Has Abstract

pub_date

1980-11-01 00:00:00

pages

1470-2

issue

11

eissn

0038-4348

issn

1541-8243

journal_volume

73

pub_type

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