Abstract:
OBJECTIVES:Cystic fibrosis (CF) is associated with vitamin D deficiency, which can lead to adverse effects including recurrent pulmonary infections and osteoporosis. We longitudinally investigated calcifediol or 25-hydroxyvitamin D (25(OH)D) levels for our pediatric patients with CF based on the time of year as well as vitamin D supplementation dosing ranges for these patients at our CF center. METHODS:We retrospectively evaluated vitamin D deficiency in our pediatric CF center for 2 years (baseline and annually) while evaluating 25(OH)D serum changes based on vitamin D supplementation, seasonality, patient age, and other factors associated with CF. RESULTS:Vitamin D supplementation was noted to be higher than current Cystic Fibrosis Foundation dosing recommendations, and no patient experienced vitamin D toxicity. Seasonality was a strong indicator of 25(OH)D levels, especially during summer or fall. Significantly fewer patients with initially low 25(OH)D levels maintained low levels at the conclusion of the study, suggesting benefit. Older patient age and higher supplemental dosing correlated with significantly lower 25(OH)D levels. CONCLUSIONS:This study suggests that targeted intervention among pediatric patients with CF living in northern latitudes of the United States, especially older children, is needed to prevent vitamin D deficiency.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Lansing AH,McDonald C,Patel RA,Meihls S,Crowell K,Chatfield B,Pohl JFdoi
10.14423/SMJ.0000000000000254subject
Has Abstractpub_date
2015-03-01 00:00:00pages
164-9issue
3eissn
0038-4348issn
1541-8243pii
SMJ14263journal_volume
108pub_type
杂志文章abstract::Plasma cell granuloma of the thyroid is a rare tumor-like lesion formed by a localized proliferation of inflammatory cells, supported by a stroma of fibrous tissue. Few cases have been previously reported in the medical literature. We report a new case of a 41-year-old man presenting a goiter with primary hypothyroidi...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-200406000-00018
更新日期:2004-06-01 00:00:00
abstract::This study was planned to determine the effectiveness of the Breese scoring system for the diagnosis of streptococcal pharyngitis and to evaluate its significance in different age groups. The research population was divided into two age groups. Group 1 consisted of children aged three and below and group 2 comprised c...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e31815a94a8
更新日期:2007-12-01 00:00:00
abstract::Buried bumper syndrome (BBS) is an uncommon complication of percutaneous endoscopic gastrostomy (PEG) tube placement. This unusual phenomenon occurs when the internal bumper of a PEG tube erodes and migrates through the gastric wall and becomes lodged anywhere between the gastric wall and the skin. If not removed and ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181fa73d0
更新日期:2010-12-01 00:00:00
abstract::Three patients seen recently at Wilford Hall USAF Medical Center emphasize the point that coccidioidomycosis may resemble lymphoma because of persistence of adenopathy on the chest roentgenogram after the initial infiltrate has resolved. Such a clinical picture strongly indicates dissemination and is probably sufficie...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197705000-00007
更新日期:1977-05-01 00:00:00
abstract::We reviewed our experience with thyroid sonography of 60 patients with nonfunctioning (cold) solitary thyroid nodules proven by iodine 123 scan. Twenty-two patients had surgery; the remaining 38 had thyroid scan and ultrasound only. In the first group, the echograms did not demonstrate the surgically proven nodules in...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198409000-00024
更新日期:1984-09-01 00:00:00
abstract::This study was done to ascertain whether there was an increased incidence of acute rheumatic fever (ARF) in west Alabama, similar to that reported elsewhere within the United States. Hospital records for the previous 10 years were reviewed and 5-year intervals were compared (1980 through 1984 vs 1985 through 1989). A ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199203000-00007
更新日期:1992-03-01 00:00:00
abstract::The purpose of this review article is to selectively examine research that was designed to evaluate the relation between religious involvement and health among older people. Four facets of religion are examined in detail: church-based social support, religious coping, forgiveness, and prayer. In addition, potential ne...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/01.SMJ.0000146488.39500.03
更新日期:2004-12-01 00:00:00
abstract::Recent research suggests that vitamin D may play a role in cardiovascular (CV) health. Although its exact role is still debated and is a matter of controversy, vitamin D deficiency has been linked to increased prevalence of CV risk factors and events. Factors that predispose persons with congestive heart failure (CHF)...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/SMJ.0b013e318213cf6b
更新日期:2011-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:Use of health services in rural communities has not been well studied. We explored how black and white children used health services in a rural Mississippi community. METHODS:Data were prospectively collected for 396 children attending a private practice to determine if race was associated wi...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.smj.0000232966.81950.a4
更新日期:2006-09-01 00:00:00
abstract::We reviewed the records of 100 consecutive patients who had gastroscopy. All endoscopic work was done by our four-man surgical group. Roentgenographic and endoscopic diagnoses are compared with reference to degree of accuracy. The expanded uses of gastroscopy in surgical practice are illustrated and a plea is made for...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197802000-00012
更新日期:1978-02-01 00:00:00
abstract::The acid-fast smear has been regarded as a poor screening technique of decreasing reliability for correct identification of diseased patients in representative hospital populations. In this report, laboratory data are reviewed from three institutions: a tertiary care facility, a regional reference laboratory, and a su...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198402000-00005
更新日期:1984-02-01 00:00:00
abstract::Maffucci's syndrome in a 17-year-old girl is reported. Since the entity was first described in 1881 by Maffucci, 105 additional cases have been recorded. Several series have reported a small but significant percentage of cases (up to 18%) with malignant change. Our case, although not particularly unique in comparison ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197804000-00033
更新日期:1978-04-01 00:00:00
abstract::Phantom sensation and phantom limb pain are two recognized sequelae of limb amputation. In most previous surveys, amputations were done for arteriosclerotic or trauma related conditions. We studied 25 patients who had lower extremity amputation for neoplasia. In studying the features of pain before and after amputatio...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198501000-00009
更新日期:1985-01-01 00:00:00
abstract::Serologic tests for the diagnosis of blastomycosis have had inadequate sensitivity, but results are improved with enzyme immunoassay (EIA) with A-antigen of Blastomyces dermatitidis. The Premier Blastomyces EIA kit (Meridian Diagnostics Inc, Cincinnati, Ohio) detected antibody against the B dermatitidis A-antigen in s...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199512000-00013
更新日期:1995-12-01 00:00:00
abstract::Three patients were treated empirically with anti-platelet agents, prednisone, plasmapheresis, and prostacyclin for the classical clinical syndrome of thrombotic thrombocytopenic purpura (TTP). All three patients initially responded, then relapsed after one to 13 months with a clinical picture characteristic of immuno...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198412000-00034
更新日期:1984-12-01 00:00:00
abstract::A resurgence of acute rheumatic fever (ARF) has been reported in many areas of the United States in recent years. We retrospectively reviewed the medical records of inpatients with a new diagnosis of ARF from 1982 through 1988 at a children's hospital that serves a six-state referral area in the mid-South. Thirty pati...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199012000-00012
更新日期:1990-12-01 00:00:00
abstract::Two premature infants were infected with HIV via blood transfusions during the neonatal period. Although neither patient had serum antibody to HIV owing to severe hypogammaglobulinemia, HIV infection was confirmed by finding HIV antigen in the sera of both patients. These cases show that HIV infection can produce seve...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198904000-00005
更新日期:1989-04-01 00:00:00
abstract:OBJECTIVES:Noninvasive assessment of right heart function and hemodynamics in patients with pulmonary arterial hypertension (PAH) is most often performed at rest, whereas the symptoms, in general, present with exertion. Assessment during exertion is limited to symptom assessment and the 6-minute walk distance. We inves...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3182805165
更新日期:2013-02-01 00:00:00
abstract::A case of carcinoma of the ampulla of Vater was diagnosed preoperatively by percutaneous transhepatic cholangiography using the Chiba needle. A dilated pancreatic duct is a radiologic sign diagnostic of early ampullary carcinoma. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197912000-00051
更新日期:1979-12-01 00:00:00
abstract::We have presented a case of pregnancy complicated by diabetes insipidus. Treatment with desmopressin acetate (DDAVP) appropriately managed the DI, and was not associated with a worsening of the condition as pregnancy progressed. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198706000-00026
更新日期:1987-06-01 00:00:00
abstract:BACKGROUND:This study was performed to examine the effect of stress on pregnancy outcome in women who underwent assisted reproductive technology (ART) procedures. METHODS:In a controlled clinical study of healthy volunteers in an academic research environment, stress was measured subjectively by administering patient ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.SMJ.0000054567.79881.E9
更新日期:2003-06-01 00:00:00
abstract::We compared personal and sexual behavior of a group of 32 young adult women who had a culture proven urinary tract infection (UTI) and a group of 28 women who had no urinary symptoms. All women were sexually active, and the two groups were similar for age, race, marital status, history of previous pregnancy, and use o...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198106000-00018
更新日期:1981-06-01 00:00:00
abstract::Most nonendocrine pancreatic neoplasms are adenocarcinomas of ductal cell or acinar origin. Primary carcinomas of the pancreas with squamous differentiation are rare enough to warrant a search for other primary tumors. In the past few decades, well-documented individual reports and large series reviews support the vie...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2000-08-01 00:00:00
abstract::As residency programs adapt to the need to promote primary care, the importance of quantitating qualitative issues increases. In this study, a questionnaire based on reported residency stressors was answered by 238 internal medicine residents. The Profile of Mood States (POMS) was also completed by 64. Factor analysis...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199507000-00010
更新日期:1995-07-01 00:00:00
abstract::Valvular heart disease accounts for considerable morbidity and some mortality among patients with end-stage renal disease (ESRD). To determine the prevalence and severity of valvular and perivalvular abnormalities, including valvular thickening, stenosis, calcification, regurgitation, and mitral annular calcification ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199501000-00009
更新日期:1995-01-01 00:00:00
abstract::We studied the prevalence of non-group-A beta-hemolytic streptococci (NGAS) in the pharyngeal cultures of symptomatic and asymptomatic children. Throat cultures were obtained by house officers in the Emergency Department at Children's Hospital of Pittsburgh to aid in the evaluation of children with symptoms or signs o...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198803000-00011
更新日期:1988-03-01 00:00:00
abstract::We have described a patient with unilateral adrenal hyperplasia, a rare cause of primary aldosteronism, and reviewed the literature on this subject. The treatment of this disorder appears to be surgical. Whether its pathogenesis is related to the more common varieties of primary aldosteronism is open to speculation. ...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198901000-00021
更新日期:1989-01-01 00:00:00
abstract::We have presented three patients in whom a striking desquamating perineal rash developed within the first five days of a febrile illness. Such a rash should raise the suspicion for Kawasaki syndrome even when all criteria are not present. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198807000-00039
更新日期:1988-07-01 00:00:00
abstract:BACKGROUND:The blood gas analyzer (BGA) has been considered the "gold standard" for pleural fluid pH determination. METHODS:We report the various methods used to measure pleural fluid pH by 277 acute care institutions who responded to a mailed questionnaire. The techniques used included the BGA (32%), dip stick or pH ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199902000-00010
更新日期:1999-02-01 00:00:00
abstract::The transition of care between pediatric and adult medicine is a challenging time for patients and physicians. This longitudinal process encompasses much more than the physical transfer of a patient between providers. Established transition of care processes and literature exist for many chronic disease populations, b...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.14423/SMJ.0000000000001017
更新日期:2019-09-01 00:00:00