Abstract:
:Recent research suggests that vitamin D may play a role in cardiovascular (CV) health. Although its exact role is still debated and is a matter of controversy, vitamin D deficiency has been linked to increased prevalence of CV risk factors and events. Factors that predispose persons with congestive heart failure (CHF) to hypovitaminosis D include nutritional deficiency, decreased skin production, reduced intestinal absorption, and hepatorenal disease. It is possible that low vitamin D can in turn aggravate CHF. The extent of deficiency can be severe enough to cause hypocalcemia, secondary hyperparathyroidism, osteomalacia, and decreased bone density. No clear data exist showing improvement in CV clinical outcomes with vitamin D replacement. Screening is advocated in most patients, although benefits of replacement are most likely to accrue in those with severe lack or with abnormalities of calcium-parathyroid-bone metabolism. According to current guidelines and research, vitamin D goals of >20 ng/ml in most patients with CHF and >30 ng/ml in those with secondary hyperparathyroidism seem to be appropriate to aim for. Further research is needed to fully unravel the association among CV risk, CHF and hypovitaminosis D, and translate this knowledge into clinically meaningful management recommendations.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Patel R,Rizvi AAdoi
10.1097/SMJ.0b013e318213cf6bsubject
Has Abstractpub_date
2011-05-01 00:00:00pages
325-30issue
5eissn
0038-4348issn
1541-8243pii
00007611-201105000-00009journal_volume
104pub_type
杂志文章,评审abstract::From 1976 to 1982, 12 children with myelodysplasia had surgery at our institution for knee flexion contractures (21 affected knees). Follow-up was a minimum of 18 months and averaged 47 months. Soft tissue lengthening of the hamstring tendons and release of the posterior capsule with or without femoral osteotomy yield...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198607000-00009
更新日期:1986-07-01 00:00:00
abstract::Swing beds contribute significantly to inpatient rehabilitation and skilled nursing care of the rural elderly, but little information is available in the general clinical literature regarding the types and outcomes of patients admitted to these programs. All swing bed admissions to a small rural hospital for the 1989 ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199212000-00008
更新日期:1992-12-01 00:00:00
abstract::We reviewed the operative complications in 333 living related donor nephrectomies done at our institution over the past 12 years. The overall complication rate was 17.1%; only three patients (0.9%) had major complications, and none died. The major complications were a delayed splenectomy because of bleeding, an adrena...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199401000-00013
更新日期:1994-01-01 00:00:00
abstract::Each year an estimated 1.3 million Americans suffer eye injuries. There is little information in the literature regarding the prevalence, demographic characteristics, and prognosis of these patients. The Eye Injury Registry of Alabama (EIRA) serves as the first and only statewide system of its kind for the collection ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198707000-00004
更新日期:1987-07-01 00:00:00
abstract::We retrospectively analyzed experience with total gastrectomy (TG) for gastric carcinoma in 23 patients. The TNM stage was I in one patient, II in one patient, III in eight patients, and IV in 13. Linitis plastica was found in ten patients. The operation was considered curative in only eight patients (35%). There were...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198908000-00011
更新日期:1989-08-01 00:00:00
abstract::Although exceedingly rare, fulminant hepatic failure (FHF) in immunocompetent patients can develop with primary or recurrent infection due to herpes simplex virus (HSV). The diagnosis is frequently obscured by the absence of mucocutaneous involvement. Elevated transaminase values with leukopenia and a relatively low b...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2000-12-01 00:00:00
abstract:OBJECTIVE:To compare mobile health (mHealth) usage by residents of West Virginia with national estimates. METHODS:Pew Research Center data from its Internet and American Life Project were accessed for secondary data analysis. These data, available to the public, are a probability sample of Internet use in the United S...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000879
更新日期:2018-10-01 00:00:00
abstract::We report a case of neutropenia and gram-negative septicemia in a 73-year-old male with ulcerative colitis. During the hospital course, medications were adjusted according to rare accounts of drug-induced neutropenia. While the substitution of propafenone for another antiarrhythmic brought about no change in the patie...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181f46647
更新日期:2010-11-01 00:00:00
abstract::From January 1979 to October 1986, 86 patients with surgically resectable adenocarcinoma of the rectum or rectosigmoid were treated with adjuvant radiotherapy consisting of preoperative 2,400 cGy (22 patients), preoperative 4,000 cGy (14 patients), "sandwich" technique (27 patients), and postoperative irradiation (23 ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199007000-00014
更新日期:1990-07-01 00:00:00
abstract::Nitrogen, derived from breakdown of dietary amino acids as ammonia, is normally converted to urea and excreted. Impairment in the conversion process (called the urea cycle) can occur, either as a consequence of primary genetic defects or through secondary suppression of enzyme activity. Either process results in hyper...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199307000-00004
更新日期:1993-07-01 00:00:00
abstract::We have reported a case of Meige's syndrome in a middle-aged man who eventually had a cerebellar degeneration syndrome. The extrapyramidal symptoms preceded cerebellar signs and symptoms by 5 years. Most patients with idiopathic Meige's syndrome show some improvement with high-dose anticholinergic therapy. Our patient...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199103000-00019
更新日期:1991-03-01 00:00:00
abstract::With the apparent indefinite postponement of the release of chymopapain for lumbar disk disorders, it seems appropriate to review critically the proliferation of proposed methods of management of this common complaint, particularly the numerous exercise regimens which have been set forth as helpful. A critical review ...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-197603000-00027
更新日期:1976-03-01 00:00:00
abstract:OBJECTIVES:The pressures for generating revenue from clinical activities dissuade clinician-educators from teaching; taking the steps to develop an educational value system is a way to recognize and perhaps support education. We compared the perceived educational value of diverse pedagogical activities during clinical ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000850
更新日期:2018-08-01 00:00:00
abstract::Disorders of the foregut are an increasingly common cause of symptoms in Western populations. This review summarizes recent advances in the understanding and treatment of gastroesophageal reflux disease, dyspepsia and celiac disease. ...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/01.smj.0000242808.91797.3d
更新日期:2007-03-01 00:00:00
abstract::Prognosis of angiosarcoma, the most common primary malignant cardiac tumor, is very poor. An early detection and treatment may extend survival beyond one year. Newer imaging modalities, including magnetic resonance imaging (MRI), play an important role in the evaluation of cardiac masses. The case of a man admitted to...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181ecfb64
更新日期:2010-10-01 00:00:00
abstract::Endobronchial tuberculosis (EBTB) is an infection of the tracheobronchial tree. A 17-year-old male patient with tuberculosis who developed middle lobe syndrome on antituberculous treatment is presented. The patient was admitted with complaints of fever, cough and weight loss. Right paracardiac and perihilar heterogene...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181b66e7a
更新日期:2009-10-01 00:00:00
abstract::To understand fully a physician's role in society, and to deal successfully with the current sense of crisis, the medical profession must evolve a world-view that appropriately relates a physician to the patient, to the practice environment, to the base of knowledge, and to the physician's own sense of self. Such a wo...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198812000-00022
更新日期:1988-12-01 00:00:00
abstract::There is controversy in the medical literature regarding the significance of "sickle cell cardiomyopathy." In an attempt to clarify this, we studied 14 patients with sickle cell anemia (age range 16 to 36 years) using simultaneous echocardiography and phonocardiography. The values of systolic time intervals and echoca...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198003000-00020
更新日期:1980-03-01 00:00:00
abstract::The female patient with a variety of genital tract symptoms offers a distinct challenge to the gynecologist. We report a case that on initial examination was thought to be pelvic inflammatory disease (PID). After further evaluation, our patient was found to be suffering from toxic shock syndrome, which in many ways ma...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199312000-00027
更新日期:1993-12-01 00:00:00
abstract:OBJECTIVES:Pulmonary arterial hypertension (PAH) is a progressive disease that can be treated with several medications. Macitentan, an endothelin receptor antagonist (ERA), has received approval as a PAH therapy. We report our data regarding the tolerability in patients with PAH who were switched from bosentan to macit...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000607
更新日期:2017-03-01 00:00:00
abstract:OBJECTIVES:Errors in drug dosing lead to poor patient outcomes and are common in patients with chronic kidney disease (CKD). Because the majority of patients with CKD are being treated by physicians specializing in internal medicine, we studied the awareness and knowledge that internal medicine resident trainees (IMRTs...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000781
更新日期:2018-03-01 00:00:00
abstract::Intracranial aneurysms often present a challenging problem for the neurosurgeon. A variety of techniques have been developed to deal with these lesions. Several subspecialists are frequently involved in such treatment. We present our experience in a community hospital using a previously described technique of hypother...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199308000-00010
更新日期:1993-08-01 00:00:00
abstract::We have presented four cases of infarcted appendices epiploicae. Because the clinical picture can be confusing, the diagnosis is frequently delayed or missed. Removal of the infarcted appendix results in cure, with no reported cases of recurrence. The disease can be fatal, four deaths having been reported in the liter...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198603000-00030
更新日期:1986-03-01 00:00:00
abstract::The percutaneous subclavian vein hemodialysis catheter, which is widely used for vascular access in patients with renal failure, can give rise to several complications. Asymptomatic stenosis or occlusion of the subclavian vein due to these catheters can lead to painful arm edema if further dialysis accesses are constr...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198803000-00004
更新日期:1988-03-01 00:00:00
abstract::This is a systematic review of the available literature and our own personal experience regarding the optimal management of the rhinoplasty patient. The routine utilization of nasal splinting, casting and perioperative antibiotics is supported. The management of a number of common early complications is also discussed...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/SMJ.0b013e3181807a79
更新日期:2008-09-01 00:00:00
abstract::A case of Rocky Mountain spotted fever in a 10-year-old boy accompanied by an unusually high degree of myalgia and muscle weakness was presented. On admission to the hospital, his creatine phosphokinase, SGOT, SGPT, and aldolase values were all abnormally high. Rash did not appear until the fourth hospital day. On the...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197812000-00037
更新日期:1978-12-01 00:00:00
abstract:OBJECTIVES:Shear wave elastography (SWE) is an emerging technology that assesses hepatic fibrosis. The aim of our study was to determine the diagnostic accuracy of General Electric (GE) Healthcare's LOGIQ E9 SWE in patients with chronic hepatitis C virus using liver biopsy as the reference standard. METHODS:The liver ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000562
更新日期:2016-11-01 00:00:00
abstract::Cardiac rupture due to blunt trauma has been recognized with increasing frequency over the past two decades. The mortality rate is high and the majority of patients die before they arrive at the emergency department. A high index of suspicion and prompt surgical intervention are crucial for survival. We report the man...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199707000-00019
更新日期:1997-07-01 00:00:00
abstract::Whipple disease (WD) is a rare disease caused by Tropheryma whipplei. The classic profile of the patient is that of a middle-aged man presenting with fever, chronic diarrhea, and arthralgias. Extragastrointestinal manifestations are not rare. A high degree of clinical suspicion for the disease is needed in atypical ca...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181d3949c
更新日期:2010-04-01 00:00:00
abstract:OBJECTIVES:To determine the documentation frequency of informed consent for women undergoing a trial of nonemergent instrumental delivery. STUDY DESIGN:A retrospective chart review of instrumented vaginal deliveries from 1992 to 2005 was performed. Cases were identified from a Labor and Delivery database and hospital ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.smj.0000243076.86803.09
更新日期:2006-12-01 00:00:00