Abstract:
:We report a case of neutropenia and gram-negative septicemia in a 73-year-old male with ulcerative colitis. During the hospital course, medications were adjusted according to rare accounts of drug-induced neutropenia. While the substitution of propafenone for another antiarrhythmic brought about no change in the patient's absolute neutrophil count, the cessation of Asacol® (Warner Chilcott, Rockaway, NJ) was followed by a significant improvement in the neutropenic state. In fact, this neutrophil count continued to trend upward for months following. We thereby conclude that Asacol® carries the potential to induce neutropenia and that this reaction may be reversed in some patients solely by discontinuing the medication and without the aid of stimulating factors such as filgrastim.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Fowler BT,Gupta T,Bilal Mdoi
10.1097/SMJ.0b013e3181f46647subject
Has Abstractpub_date
2010-11-01 00:00:00pages
1167-9issue
11eissn
0038-4348issn
1541-8243journal_volume
103pub_type
杂志文章abstract::We have presented four cases of infarcted appendices epiploicae. Because the clinical picture can be confusing, the diagnosis is frequently delayed or missed. Removal of the infarcted appendix results in cure, with no reported cases of recurrence. The disease can be fatal, four deaths having been reported in the liter...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198603000-00030
更新日期:1986-03-01 00:00:00
abstract::To determine the prevalence of frequently occurring neurologic disorders in a biracial population, a survey of households and chronic care institutions was carried out for all residents of Copiah County, Mississippi. Along with a complete census, interviews were held using extensive questions about diagnoses, signs, a...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198703000-00016
更新日期:1987-03-01 00:00:00
abstract:BACKGROUND:The incidence of prostate cancer in black men is estimated to be 30% to 50% higher than among age-matched white men, and black men have a twofold higher mortality rate. To determine whether racial differences exist in men with similarly staged disease, we compared clinical and pathologic features in black an...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2000-04-01 00:00:00
abstract::The role of the otolaryngologist in the diagnosis and management of cerebrospinal fluid rhinorrhea is discussed. One hundred eight cases of cerebrospinal rhinorrhea were studied with emphasis on cause, localization, and treatment. Extracranial approaches produce minimal morbidity and should be considered as possible t...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197512000-00015
更新日期:1975-12-01 00:00:00
abstract::Tramadol (Ultram) is a new analgesic agent with a dual mechanism of action that includes weak agonistic effects at the mu-opioid receptor as well as inhibition of neurotransmitter (serotonin, norepinephrine) re-uptake. Although it has proven to be a safe and effective agent for the control of pain, adverse effects can...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199708000-00010
更新日期:1997-08-01 00:00:00
abstract:BACKGROUND:This study examined patient perceptions and attitudes toward various aspects of the male and female physician's professional appearance in the family practice setting. METHODS:Four hundred ninety-six patients from two family practice clinics in Knoxville, Tennessee, completed a valid and reliable questionna...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.SMJ.0000077011.58103.C1
更新日期:2003-12-01 00:00:00
abstract::Retrospective review of eight years' experience with the Mallory-Weiss syndrome emphatically supports the need for accurate, early localization of the site of upper gastrointestinal hemorrhage. Pertinent aspects of the history and physical and laboratory evaluation of this group of patients were analyzed to determine ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1979-10-01 00:00:00
abstract:BACKGROUND:Many hospitalized anemic patients do not undergo appropriate evaluation. We hypothesized that specific clinical variables were likely to be important in triggering evaluation for iron deficiency anemia. METHODS:We prospectively identified 637 consecutive anemic patients without acute gastrointestinal bleedi...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181520392
更新日期:2007-10-01 00:00:00
abstract::Primary small cell undifferentiated carcinomas (SCUCs) are unusual tumors of the colon and rectum. Histologically, these lesions represent a spectrum of neuroendocrine differentiation, with oat cell carcinoma being the most primitive subtype and carcinoid tumors being the most differentiated. This observation is suppo...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199609000-00016
更新日期:1996-09-01 00:00:00
abstract::Many health care providers practicing near the border between the United States and Mexico have serious concerns about their patients' using medications obtained in Mexico. Despite these concerns, the extent of this problem is not known. A survey administered in a publicly funded rural clinic and an urban private prac...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199003000-00003
更新日期:1990-03-01 00:00:00
abstract::We have described a case in which prenatal ultrasonography showed a defect in the fetal abdominal wall. By further careful evaluation gastroschisis was diagnosed, allowing a planned delivery in a tertiary care center where specialized personnel were immediately available to treat the neonate. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198402000-00036
更新日期:1984-02-01 00:00:00
abstract::The value of splenoportography in evaluating patients with portal hypertension was assessed. The technic was found to be useful in estimating portal-venous pressure, ruling out portal vein thrombosis, evaluating the superior mesenteric and portal veins as to their suitability for shunt procedures, and defining anatomy...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197710000-00017
更新日期:1977-10-01 00:00:00
abstract::Restorative proctocolectomy with ileal pouch anal anastomosis has become the most commonly used procedure for elective treatment of patients with mucosal ulcerative colitis and familial adenomatous polyposis. Since its original description, the procedure has been modified in an attempt to obtain optimal functional res...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/01.SMJ.0000047720.97917.03
更新日期:2003-01-01 00:00:00
abstract::Millions of concussions occur every year in the United States. The public interest in concussion has increased after a number of high-profile deaths in high school athletes from sports-related head trauma and in some professional athletes from chronic traumatic encephalopathy. One of the most active areas of research ...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/SMJ.0000000000000064
更新日期:2014-02-01 00:00:00
abstract::In a series of 565 morbidly obese patients having one of five gastric bariatric procedures done at North Carolina Memorial Hospital between May 1975 and December 1982, 55 patients had 58 complications requiring reoperation. These complications included a leak from the stomach or anastomosis, stomal obstruction, and su...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198505000-00009
更新日期:1985-05-01 00:00:00
abstract::Valvular heart disease accounts for considerable morbidity and some mortality among patients with end-stage renal disease (ESRD). To determine the prevalence and severity of valvular and perivalvular abnormalities, including valvular thickening, stenosis, calcification, regurgitation, and mitral annular calcification ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199501000-00009
更新日期:1995-01-01 00:00:00
abstract::We have described a 38-year-old white American woman who had a 7-year history of pain in the left anterior chest, neck, right wrist, and buttocks. The pain fluctuated in severity and appeared to coincide with worsening of her skin condition, palmoplantar pustulosis (PPP). She manifested the typical skeletal features o...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199304000-00021
更新日期:1993-04-01 00:00:00
abstract::We report on two healthy white men who sustained high-voltage electrical burns and were transferred to our regional burn center for specialized care. Within 24 hours of admission, both patients developed clinical signs and laboratory evidence of diabetes insipidus. With appropriate treatment, no sequelae occurred and ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199403000-00025
更新日期:1994-03-01 00:00:00
abstract::We have described a case of peripelvic extravasation of urine caused by lower ureteral obstruction from a breech presentation in a 20-year-old primigravida. The patient was successfully treated with cesarean section to relieve the obstruction, and systemic antibiotics. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198006000-00043
更新日期:1980-06-01 00:00:00
abstract::This paper reports results of a project designed to examine factors related to compliance with referral for follow-up and treatment of cervical dysplasia. Women studied had cervical dysplasia diagnosed by Pap smear between May 1989 and April 1990. These women had regular follow-up at the gynecology clinic of the Reyno...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199201000-00003
更新日期:1992-01-01 00:00:00
abstract::The association of hypercoagulation and cancer, a well established pattern of disease, often leads to pulmonary emboli in an already compromised patient. Anticoagulation therapy in these patients is occasionally complicated by several factors including thrombocytopenia, which may result in a life-threatening situation...
journal_title:Southern medical journal
pub_type: 临床试验,杂志文章
doi:
更新日期:1987-10-01 00:00:00
abstract::I have reported three case of paraurethral cysts in female neonates. These are uncommon lesions, and urologic evaluation is required to differentiate them from ectopic ureteroceles, urethral diverticula, or paraurethral tumors. Histologic appearance of the cyst epithelium identifies the embryologic origin. The cysts e...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198506000-00035
更新日期:1985-06-01 00:00:00
abstract::As our population ages, the incidence and prevalence of Alzheimer disease (AD) will increase dramatically. A number of therapies have been investigated for the treatment and prevention of AD. Clinicians should be prepared to provide evidence-based answers to inquiries regarding AD treatment. There is insufficient evid...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/01.SMJ.0000166671.86815.C1
更新日期:2005-06-01 00:00:00
abstract::We reviewed the operative complications in 333 living related donor nephrectomies done at our institution over the past 12 years. The overall complication rate was 17.1%; only three patients (0.9%) had major complications, and none died. The major complications were a delayed splenectomy because of bleeding, an adrena...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199401000-00013
更新日期:1994-01-01 00:00:00
abstract:OBJECTIVE:To provide a succinct and updated discussion on common ear, nose, and throat (ENT) disorders encountered by primary care physicians. METHODS:Review of recent and pertinent literature. RESULTS:Recent data was identified via a PubMed search as well as commonly utilized texts in otolaryngology. DISCUSSION:Whi...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/01.smj.0000233214.49561.c1
更新日期:2006-10-01 00:00:00
abstract::A patient with pathologically proven acrometastasis of his left thumb presented 3 months after esophagectomy for esophageal squamous cell carcinoma. Interestingly, there was indeed a faint uptake in his left thumb that was initially considered an artifact in the whole body bone scan taken before esophagectomy. Physici...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e31817bf9be
更新日期:2008-11-01 00:00:00
abstract::Conventional rate limits for sinus rhythm--100/min as the tachycardia threshold and 60/min as the bradycardia threshold--were established by consensus and never formally examined. Because clinical experience indicated that both figures were too high, we investigated this formally in 500 normal individuals. Results wer...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199607000-00003
更新日期:1996-07-01 00:00:00
abstract:OBJECTIVES:Patients with cirrhosis have a high rate of 30-day hospital readmission that affects their quality of life and contributes to increased healthcare-related costs. The aim of our study was to identify frequency, predictors, and preventable causes of hospital readmissions among patients with decompensated cirrh...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000371
更新日期:2015-11-01 00:00:00
abstract::To determine sensitivity and specificity of magnetic resonance imaging (MRI) and ultrasonography (US) in the detection of breast implant rupture, and also to determine the relative merits of clinical examination and mammography, we studied 81 patients (160 implants). All patients had implants removed, thus allowing co...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199604000-00009
更新日期:1996-04-01 00:00:00
abstract::We reviewed the records of patients with cecal volvulus at three affiliated hospitals of Eastern Virginia Medical School to elucidate its incidence, patterns of presentation, and current methods of surgical management. We identified 109 patients in whom a discharge diagnosis of intestinal obstruction due to volvulus w...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1988-10-01 00:00:00