Cerebellar degeneration and Meige's syndrome.

Abstract:

:We have reported a case of Meige's syndrome in a middle-aged man who eventually had a cerebellar degeneration syndrome. The extrapyramidal symptoms preceded cerebellar signs and symptoms by 5 years. Most patients with idiopathic Meige's syndrome show some improvement with high-dose anticholinergic therapy. Our patient's lack of response to such agents and his subsequent cerebellar symptoms are reminiscent of the situation seen with parkinsonian patients who do not respond to medications, indicating a more widespread degenerative disease. The association of extrapyramidal symptoms with some spinocerebellar disorders, and the pathologic changes seen in the one reported autopsy case, should place the group of spinocerebellar disorders high on the differential list.

journal_name

South Med J

journal_title

Southern medical journal

authors

Khara JS,Calabrese VP

doi

10.1097/00007611-199103000-00019

subject

Has Abstract

pub_date

1991-03-01 00:00:00

pages

387-9

issue

3

eissn

0038-4348

issn

1541-8243

journal_volume

84

pub_type

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