Idiopathic thrombocytopenic purpura during remission of thrombotic thrombocytopenic purpura.

Abstract:

:Three patients were treated empirically with anti-platelet agents, prednisone, plasmapheresis, and prostacyclin for the classical clinical syndrome of thrombotic thrombocytopenic purpura (TTP). All three patients initially responded, then relapsed after one to 13 months with a clinical picture characteristic of immunogenic thrombocytopenic purpura (ITP). At relapse, all three had thrombocytopenia without microangiopathy or other causes of thrombocytopenia. All responded to splenectomy. This complication of TTP may become more common with improved survival in TTP. Recognition may prevent inappropriate therapy.

journal_name

South Med J

journal_title

Southern medical journal

authors

Stein RS,Flexner JM

doi

10.1097/00007611-198412000-00034

subject

Has Abstract

pub_date

1984-12-01 00:00:00

pages

1599-601

issue

12

eissn

0038-4348

issn

1541-8243

journal_volume

77

pub_type

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