Plasma cell granuloma of the thyroid and Hashimoto thyroiditis.

Abstract:

:Plasma cell granuloma of the thyroid is a rare tumor-like lesion formed by a localized proliferation of inflammatory cells, supported by a stroma of fibrous tissue. Few cases have been previously reported in the medical literature. We report a new case of a 41-year-old man presenting a goiter with primary hypothyroidism (thyroid-stimulating hormone, 70 mIU/L; free thyroxine, < 0.01 pmol/L; triiodothyronine, 0.66 nmol/L) and elevation of thyroid antibodies. Several fine-needle aspiration biopsies of the thyroid were fruitless and total thyroidectomy was performed. Histologic and immunohistochemical study demonstrated the polyclonal nature of the cells and yielded a diagnosis of plasma cell granuloma. Histologic findings of Hashimoto thyroiditis were present too.

journal_name

South Med J

journal_title

Southern medical journal

authors

Ferrer-García JC,Costa-Talens P,Merino-Torres JF,Prieto-Rodríguez M,Vera-Sempere JF,Piñón-Sellés F

doi

10.1097/00007611-200406000-00018

subject

Has Abstract

pub_date

2004-06-01 00:00:00

pages

598-600

issue

6

eissn

0038-4348

issn

1541-8243

journal_volume

97

pub_type

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