Abstract:
:A 35-year-old, previously healthy woman, known to be thyrotoxic, was transferred from a community hospital for "acute abdomen." Abdominal pain, distention, and hyperemesis resolved with placement of nasogastric tube (NGT) and return of 2,600 mL of bilious fluid. Continued high NGT output made oral or NGT administration of antithyroid drugs impossible. We gave propylthiouracil (PTU) by retention enemas with therapeutic serum levels and sublingual saturated solution of potassium iodide (SSKI) with 70% absorption based on 24-hour free iodine urinary excretion. The patient's thyroxine (T4) and triiodothyronine (T3) radioimmunoassays were normal on hospital days 10 and 12, respectively. However, free T4 and T3 resin uptake did not normalize until hospital day 31. On hospital day 32, she tolerated removal of NGT without nausea and 4 days later was taking a regular diet. We conclude that our patient's gastrointestinal symptoms were a prominent feature of her thyrotoxicosis and that rectal PTU and sublingual SSKI are effective in administration of antithyroid drugs.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Cansler CL,Latham JA,Brown PM Jr,Chapman WH,Magner JAdoi
10.1097/00007611-199711000-00018subject
Has Abstractpub_date
1997-11-01 00:00:00pages
1143-6issue
11eissn
0038-4348issn
1541-8243journal_volume
90pub_type
杂志文章abstract::Three patients seen recently at Wilford Hall USAF Medical Center emphasize the point that coccidioidomycosis may resemble lymphoma because of persistence of adenopathy on the chest roentgenogram after the initial infiltrate has resolved. Such a clinical picture strongly indicates dissemination and is probably sufficie...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197705000-00007
更新日期:1977-05-01 00:00:00
abstract::Lyme disease, now the most common tick-borne illness in the United States, has recently received much media attention, due in part to its potentially serious sequelae in untreated patients. Because a rare patient with late illness may lack antibodies to the etiologic agent, Borrelia burgdorferi, physicians may be temp...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199110000-00024
更新日期:1991-10-01 00:00:00
abstract::Two cases of postoperative death due to unsuspected pheochromocytoma are presented. Both patients exhibited signs and symptoms preoperatively which might have been attributable to a pheochromocytoma. These reports serve as a reminder of the potentially fatal consequences of inadequate evaluation of hypertensive patien...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197711000-00023
更新日期:1977-11-01 00:00:00
abstract::Brown recluse spider bites are usually self-limited skin lesions that infrequently progress to bullae, ulceration, and scarring. We treated a patient with a documented brown recluse bite who had recurring lesions resembling pyoderma gangrenosum (PG) that persisted for months. Three other patients referred to Vanderbil...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198503000-00012
更新日期:1985-03-01 00:00:00
abstract::A prospective study of 45 granulocyte transfusions in children using continuous flow centrifugation is reported. During 13 episodes of proven or presumed infection, only two children failed to show a favorable response to granulocyte transfusion. The neutropenic child shows a significantly increased absolute granulocy...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197703000-00017
更新日期:1977-03-01 00:00:00
abstract::We have described three cases of adenomyoma of the stomach. These benign lesions are found almost exclusively in the antrum or pylorus and are composed of combinations of ducts, glands, pancreatic tissue, and smooth muscle. Malignancy arising in adenomyomas is rare. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198410000-00037
更新日期:1984-10-01 00:00:00
abstract:OBJECTIVE:Intraventricular hemorrhage (IVH) represents a clinicopathologic entity with a dismal prognosis. The associated mortality rate has been reported as high as 80%; the morbidity is also quite high. The use of various fibrinolytic agents (streptokinase, urokinase, and recombinant tissue-type plasminogen activator...
journal_title:Southern medical journal
pub_type: 临床试验,杂志文章
doi:10.1097/01.smj.0000170732.24324.ea
更新日期:2005-08-01 00:00:00
abstract::Patent ductus arteriosus (PDA) is a malady usually identified during childhood. Prompt surgical correction provides definitive therapy with long-term survival. When not corrected, PDA leads to significant morbidity and mortality, making it a rare condition in the adult population. We report the case of a 44-year-old m...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:
更新日期:2001-03-01 00:00:00
abstract::Extraskeletal dedifferentiated chondrosarcomas (DC) are uncommon tumors that predominantly occur in the head and neck. Herein, we describe a case of pulmonary DC detected in a patient with systemic sclerosis and presenting with a symptomatic large pleural effusion and a pulmonary lobar consolidation on chest imaging. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181ad6236
更新日期:2009-08-01 00:00:00
abstract:OBJECTIVE:To compare mobile health (mHealth) usage by residents of West Virginia with national estimates. METHODS:Pew Research Center data from its Internet and American Life Project were accessed for secondary data analysis. These data, available to the public, are a probability sample of Internet use in the United S...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000879
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVES:Pancreatic steatosis in adults has been proposed to be associated with obesity; however, data on pancreatic steatosis in children are lacking. Our study aimed to measure the prevalence of pancreatic steatosis in children and to examine its association with obesity and nonalcoholic fatty liver disease. METHO...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000432
更新日期:2016-03-01 00:00:00
abstract::Continent reconstruction of the lower urinary tract using the appendicovesicostomy (Mitrofanoff principle) is an excellent means of managing many patients with altered bladder function, especially those with good bladder volume and low pressure. Motivated patients unable to perform urethral catheterization because of ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199410000-00009
更新日期:1994-10-01 00:00:00
abstract::Clinicians should be on the alert for the possibility of underlying thyrotoxicosis in patients having an affective disturbance. An initial detailed medical history and complete physical examination is essential even in severely agitated, threatening patients. The danger of inappropriate diagnosis and treatment of thes...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198811000-00032
更新日期:1988-11-01 00:00:00
abstract::Sixteen patients with spinal epidural compression by metastatic small-cell lung cancer were given radiotherapy for palliation. Lower limb motor deficit was the most prominent clinical manifestation. Neurologic dysfunction was commonly present for more than 48 hours before the diagnosis of compression. Median interval ...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199203000-00008
更新日期:1992-03-01 00:00:00
abstract::This case presents a rare type of crescentic glomerulonephritis characterized as IgA deposits predominantly along the glomerular basement membranes (GBM). The patient clinically manifested with rapidly progressive glomerulonephritis (RPGN) without pulmonary hemorrhage or vasculitis-related systematic symptoms. No posi...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181817c22
更新日期:2008-09-01 00:00:00
abstract::Liver cysts are a well-recognized feature of autosomal dominant polycystic kidney disease (ADPKD) and occur in 77% of patients more than 60 years old. Serious sequelae, however, are rare, the two most common complications being pain and cyst infections. Portal hypertension has been reported in ADPKD due to the rare pr...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199906000-00015
更新日期:1999-06-01 00:00:00
abstract:OBJECTIVES:We sought to evaluate whether there is a sex difference in the analgesic response to mu versus kappa opioids in the management of acute moderate to severe pain of injury in the emergency department. METHODS:The study was a randomized, double-blind, clinical trial comparing the prototypical mu-receptor agoni...
journal_title:Southern medical journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/01.smj.0000085743.68121.a9
更新日期:2004-01-01 00:00:00
abstract::We describe a case of an adrenal incidentalomas in the setting of congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency. The adrenal mass was shown to be a cavernous hemangioma. Such neoplasms are rare but have the risk of retroperitoneal hemorrhage and may be difficult to differentiate from malignant ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1998-08-01 00:00:00
abstract::Nonspherocytic hemolytic anemia was diagnosed in a 34-year-old man with jaundice since childhood. Splenectomy at the age of 8 had no influence on the anemia. Bronze diabetes was diagnosed at age 31, presumably due to hemosiderosis and secondary hemochromatosis. Iron chelation was unsuccessful in controlling iron overl...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198505000-00027
更新日期:1985-05-01 00:00:00
abstract::Seven patients with diabetes of ten to 24 years' duration and renal insufficiency were treated with fluphenazine and amitriptyline in an attempt to control severe pain in the extremities. Six patients had relief of pain within five days of initiation of therapy. One patient had no pain relief despite mood alteration. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1983-04-01 00:00:00
abstract::A bulging fissure sign was noticed on chest roentgenogram in a patient with H influenzae pneumonia. This sign is usually associated with Klebsiella pneumonia and has also been seen in pneumococcal and plague pneumonia, tuberculosis, mass lesions of the lung, and large lung abscesses. This is thought to be the first re...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197811000-00048
更新日期:1978-11-01 00:00:00
abstract::Seven adults with acute leukemia had a clinical and radiologic diagnosis of neutropenic enterocolitis. Six of the seven patients had granulocyte counts less than 500/microliter. All seven patients responded to intensive medical therapy, including bowel rest, broad spectrum antibiotics, and white blood cell transfusion...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198710000-00008
更新日期:1987-10-01 00:00:00
abstract::Sickle cell trait is present in about 8% of black Americans, and clinically significant sickling disorders are common in this population. These disorders can be accurately defined by combinations of quantitative hemoglobin electrophoresis at alkaline pH, citrate agar electrophoresis, solubility tests for sickle hemogl...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197804000-00021
更新日期:1978-04-01 00:00:00
abstract:BACKGROUND:Primary care providers (PCPs) have limited training in recognizing common skin disorders, and additional emphasis may be placed on laboratory evaluation, including skin biopsies. METHODS:Primary care providers in Miami, Fla, were surveyed regarding skin biopsy and excision practices and histologic interpret...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2001-05-01 00:00:00
abstract::As endoscopic surgery comes into its own, the applications of this modality are increasing. This is well illustrated by the use of endoscopic polypectomy in the colon, and more recently by endoscopic polypectomy in the stomach and duodenum. We can anticipate increased applicability of these technics as the experience ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197605000-00032
更新日期:1976-05-01 00:00:00
abstract::Hyponatremia has been recognized as a complication in adults with acquired immunodeficiency syndrome (AIDS). We did a retrospective study evaluating the medical records of 86 children (age 4 months to 21 years) with human immunodeficiency virus (HIV-1) infection to determine the frequency and clinical associations of ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199510000-00008
更新日期:1995-10-01 00:00:00
abstract::Seizures are common in acute exacerbations of hepatic porphyria, even though the etiology is not identified in most cases. We have reported a case of normeperidine-induced seizures in a patient with hereditary coproporphyria. Although meperidine is commonly used for pain control during acute attacks in these patients,...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199011000-00020
更新日期:1990-11-01 00:00:00
abstract::Pyridium (phenazopyridine hydrochloride) is often prescribed as an analgesic in patients following trauma, surgery, or infections of the urinary tract. Pyridium toxicity has been previously reported, however, most cases result in a single adverse effect. Herein the authors describe an elderly patient who presented wit...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.smj.0000197299.77949.16
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVES:The use of monitored anesthesia care (MAC) for colonoscopy sedation continues to increase. This study examined trends during a 9-year period in the use of MAC and explored which patient variables may have influenced these trends. METHODS:This was a retrospective review of all colonoscopies performed in our ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000338
更新日期:2015-09-01 00:00:00
abstract::Many psychiatric patients experience pharmaceutical intolerances, and some of them do not derive optimal efficacy from their pharmacotherapies. Clinical problems such as these may result in prolonged dysfunction, adverse consequences, and repeated changes in medication treatment regimens. Pharmacogenomics is a laborat...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000534
更新日期:2016-10-01 00:00:00