Radiotherapeutic palliation of spinal epidural compression in small-cell lung cancer.

Abstract:

:Sixteen patients with spinal epidural compression by metastatic small-cell lung cancer were given radiotherapy for palliation. Lower limb motor deficit was the most prominent clinical manifestation. Neurologic dysfunction was commonly present for more than 48 hours before the diagnosis of compression. Median interval between diagnosis of lung cancer and epidural tumor was 8.5 months. Twelve percent of the patients survived for 1 year after diagnosis of epidural compression. Radiotherapy gave significant pain relief to eight (89%) of the symptomatic individuals. Among those whose status could be assessed, one third of the initially nonambulatory patients (n = 9) were able to walk again. Anal or bladder sphincter or sensory disturbance did not improve in four persons. Radiotherapy for spinal epidural compression in small-cell lung cancer, though not curative, is highly effective in the relief of pain and may ameliorate limb motor dysfunction in some patients.

journal_name

South Med J

journal_title

Southern medical journal

authors

Ampil FL,Abreo F

doi

10.1097/00007611-199203000-00008

subject

Has Abstract

pub_date

1992-03-01 00:00:00

pages

266-9

issue

3

eissn

0038-4348

issn

1541-8243

journal_volume

85

pub_type

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