Abstract:
OBJECTIVES:We sought to evaluate whether there is a sex difference in the analgesic response to mu versus kappa opioids in the management of acute moderate to severe pain of injury in the emergency department. METHODS:The study was a randomized, double-blind, clinical trial comparing the prototypical mu-receptor agonist, morphine sulfate, to the prototypical kappa agonist, butorphanol. The primary endpoints were degree of relief by visual analog scores at 30 and 60 minutes. Statistical analysis was performed using Mann-Whitney Utest for nonparametric analysis and repeated-measures analysis of variance. RESULTS:Ninety-four patients were entered in the study, with 49 (52%) males and 45 (48%) females. Forty-six received morphine sulfate and 48 received butorphanol. There was no difference in demographics in the two groups. At 60 minutes, females had significantly lower visual analog scores with butorphanol compared with morphine (P = 0.046). At 60 minutes, there was a trend for a difference in response of males versus females to morphine, with males responding better than females (P = 0.06). CONCLUSION:Females had better pain scores with butorphanol than morphine at 60 minutes.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Miller PL,Ernst AAdoi
10.1097/01.smj.0000085743.68121.a9subject
Has Abstractpub_date
2004-01-01 00:00:00pages
35-41issue
1eissn
0038-4348issn
1541-8243journal_volume
97pub_type
临床试验,杂志文章,随机对照试验abstract:OBJECTIVES:Accurate reptile envenomation mortality data for the United States is unavailable. Using data from the National Vital Statistics System (NVSS), deaths from 1979 through 1998 were analyzed. METHODS:Records of deaths from reptile envenomation were selected using matches to code E905.0 of the International Cla...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-200407000-00006
更新日期:2004-07-01 00:00:00
abstract::Penetrating neck trauma may be managed operatively or nonoperatively, depending on precise anatomic location. Conservative management of zone II injuries is currently an issue under debate. We present a brief case report followed by a description of the current strategies for operative exploration and diagnostic maneu...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2000-06-01 00:00:00
abstract:BACKGROUND:This study was done to determine the accuracy of the 2 x 2 cm pocket identifying low amniotic fluid (AF) volume in singleton and twin pregnancies. METHODS:The AF volume was evaluated by ultrasonography for the presence of a 2 x 2 cm pocket before amniocentesis. The actual AF volume was then determined by a ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199908000-00011
更新日期:1999-08-01 00:00:00
abstract::Even though epidural analgesia is effective and has advantages over conventional postoperative analgesia, it is also labor intensive, requiring 24-hour supervision by an anesthesiologist. In an effort to decrease the manpower requirements, some hospitals allow the nursing staff to administer epidural narcotics to adul...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199204000-00012
更新日期:1992-04-01 00:00:00
abstract::Sickle cell disease (SCD) is the most common hereditary disorder and affects 30 million people worldwide. Advances in science have improved overall survival in patients with SCD and as such, more patients are reaching reproductive age and are becoming pregnant. SCD in pregnancy leads to multiple complications that put...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.14423/SMJ.0000000000000514
更新日期:2016-09-01 00:00:00
abstract::Lyme disease, now the most common tick-borne illness in the United States, has recently received much media attention, due in part to its potentially serious sequelae in untreated patients. Because a rare patient with late illness may lack antibodies to the etiologic agent, Borrelia burgdorferi, physicians may be temp...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199110000-00024
更新日期:1991-10-01 00:00:00
abstract::As with our case, patients with rupture of the atrium may survive untreated for prolonged periods. Although three survivors have been reported after rupture of the right or left ventricle, ventricular injuries are usually fatal. With improvements in transportation methods, rapid recognition and diagnosis, and early op...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198604000-00027
更新日期:1986-04-01 00:00:00
abstract::We have reported a case of reversible acute renal transplant failure due to the Page kidney phenomenon, which followed routine diagnostic needle biopsy. Duplex Doppler ultrasonography differentiated between allograft rejection and graft failure due to perirenal and mechanical abnormalities. Renal transplant failure ma...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199305000-00019
更新日期:1993-05-01 00:00:00
abstract::This case report describes an accidental ingestion of a gold dental inlay prosthesis that became lodged in the appendix. A nonsurgical approach was pursued because this blunt foreign body posed a minimal perforation risk. A second opinion for an elective appendectomy was chosen by the patient until a preoperative abdo...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199807000-00012
更新日期:1998-07-01 00:00:00
abstract::Subacute bacterial endocarditis in a 72-year-old woman was found to be caused by nutritionally deficient ("satelliting") Streptococcus sanguis. The organism, which required pyridoxal compounds or thiol substitutes, was identified after the application of relatively unusual but simple laboratory procedures. Normally, t...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1980-12-01 00:00:00
abstract::We have reported a case of a large paraesophageal herniation with a small sliding component. Abnormal positioning of the esophagogastric junction or the necessity for mobilizing it during repair requires the addition of an antireflux procedure to the standard reduction and repair. Elective repair of a paraesophageal h...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198809000-00027
更新日期:1988-09-01 00:00:00
abstract::Early gradual ambulation is currently recommended for patients with acute low back pain if results of neurologic examination are normal. Bed rest for up to 2 days is considered optimal. To assess management practices, we retrospectively reviewed the medical records of individuals with acute back pain treated at three ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1991-05-01 00:00:00
abstract::A 76-year-old man with chronic obstructive pulmonary disease who developed P multocida pneumonia and bacteremia has been described. The infection was treated with antibiotics, and the patient recovered. Pasteurella multocida is known to infect many species of animals. The instances of human infection due to this organ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197709000-00035
更新日期:1977-09-01 00:00:00
abstract::Between 1975 and 1978, over 200 knee arthroscopies were performed at the Emory University Hospitals; the findings were totally correct in 91%. During the same period, arthrograms were performed on 79 different patients, 39 of whom had confirming arthrotomies. The arthrograms were totally correct in 38%. Fifteen totall...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198111000-00009
更新日期:1981-11-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to determine the relation among multiple morbidities and the prevalence of colorectal cancer (CRC) screening among older adult Appalachian residents of Kentucky. This is the first known study to address multiple morbidities exclusively with a health-disparities population. METH...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e31823a8879
更新日期:2011-12-01 00:00:00
abstract:OBJECTIVE:Our study aimed to investigate the association between maternal-perceived psychological stress and fetal telomere length. METHODS:We recruited women in labor upon hospital delivery admission. Based on responses to the Perceived Stress Scale, we categorized participants as having "high," "normal," or "low" pe...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000567
更新日期:2016-12-01 00:00:00
abstract::This report describes a cocaine user who presented with polymorphonuclear pleocytosis in cerebrospinal fluid mimicking bacterial meningitis. Thorough investigation of the cerebrospinal fluid did not reveal evidence of bacteria or fungi. Clinical deterioration was observed in spite of empiric treatment with antibiotics...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.SMJ.0000082002.66513.EA
更新日期:2003-09-01 00:00:00
abstract::Radiation therapy and/or chemotherapy are the treatment modalities of choice in lymphomas. Except for Burkitt's tumor, surgery is usually indicated only when percutaneous biopsy fails to establish the histologic diagnosis. We have described a patient with glomerulonephritis and anasarca secondary to an IgM-producing p...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198211000-00030
更新日期:1982-11-01 00:00:00
abstract:OBJECTIVE:Satiety is the perception of satisfied fullness and represents a summation of neural and hormonal influences. Satiety can be assessed by drink tests, including water load. The objective of our study was to confirm the difference in water load volume between nonobese control children and children with function...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000612
更新日期:2017-03-01 00:00:00
abstract:OBJECTIVES:Patients with cirrhosis have a high rate of 30-day hospital readmission that affects their quality of life and contributes to increased healthcare-related costs. The aim of our study was to identify frequency, predictors, and preventable causes of hospital readmissions among patients with decompensated cirrh...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000371
更新日期:2015-11-01 00:00:00
abstract::We reviewed the records of 101 patients over the age of 60 who had exploration and cholecystectomy in 1982 at Norfolk General Hospital. There were 52 elective and 49 emergency cases. Women comprised 57.4% of the patients, and almost 50% of the patients were over the age of 70. Forty-nine percent of the cases were emer...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198704000-00016
更新日期:1987-04-01 00:00:00
abstract::The risk of suicidal behavior associated with antidepressant treatment is an issue of debate and concern. The US FDA has required that antidepressants carry a black box warning that there may be a risk of suicidal ideations in depressed pediatric patients treated with these medications, and recently extended the warni...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/SMJ.0b013e3181a918bd
更新日期:2009-07-01 00:00:00
abstract::A 36-year-old man was found to have severe pulmonary hypertension and a right-to-left shunt secondary to a patent ductus arteriosus. Attempt at surgical closure was unsuccessful. The patient was followed up for 21 years, and his only significant medical problem is leg weakness to moderate exertion. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198005000-00036
更新日期:1980-05-01 00:00:00
abstract::A 64-year-old female patient presented with acute cerebellar ataxia. After ruling out vascular, infectious, metastatic, demyelinating, and medication etiologies, a paraneoplastic origin for her illness was determined. A renal mass was discovered and found to be renal cell carcinoma. Her symptoms resolved after a radic...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e31816bea80
更新日期:2008-05-01 00:00:00
abstract:OBJECTIVES:Patients awaiting heart transplantation can be listed for prolonged periods of time and, as a result, the prevalence of anxiety and depression is high. Our study evaluates the feasibility of canine-assisted therapy (CAT) in this population. METHODS:A prospective, multicenter study was performed on all statu...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000980
更新日期:2019-06-01 00:00:00
abstract::An autopsy of a probable case of MCLS is described. After 10,000 cases have been recorded in Japan, the disease is being recognized in the United States. There may be an overlap with infantile periarteritis nodosa. Pathologic studies of fatal cases of MCLS diagnosed during life have not been reported in this country. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197809000-00040
更新日期:1978-09-01 00:00:00
abstract:BACKGROUND:Several previous studies of invasive Group A streptococcal (GAS) disease have been hindered by small sample sizes (< or = 100 patients) and limited generalizability. METHODS:We conducted a population-based study of invasive GAS disease. The objectives of the study were to describe the clinical features of i...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.SMJ.0000051060.95210.9A
更新日期:2003-10-01 00:00:00
abstract::Parameters for significant risk of aspiration have been defined as a gastric pH less than 2.5 and/or a volume greater than 25 ml. We investigated the effects of metoclopramide and cimetidine, alone and in combination, on the pH and volume of gastric contents of patients taking nothing by mouth before general anesthesi...
journal_title:Southern medical journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00007611-198611000-00009
更新日期:1986-11-01 00:00:00
abstract::We have described a case of chronic pancreatitis due to stenosing papillitis relieved by sphincteroplasty and removal of pancreatic duct stones, as opposed to a major pancreatic resection. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198310000-00033
更新日期:1983-10-01 00:00:00
abstract::Early recognition and prompt intervention are the most crucial steps in the management of gallstone-induced biliary disease. Many conditions can mimic the presentation of gallstone-induced complications. Therefore, participation of a clinically astute physician is essential in evaluating symptoms and interpreting diag...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2000-03-01 00:00:00