Abstract:
:Lyme disease, now the most common tick-borne illness in the United States, has recently received much media attention, due in part to its potentially serious sequelae in untreated patients. Because a rare patient with late illness may lack antibodies to the etiologic agent, Borrelia burgdorferi, physicians may be tempted to give empiric antibiotics for illnesses that may not be Lyme disease. We have described a patient who, despite negative laboratory evidence for late Lyme disease, was treated for 3 weeks with intravenous ceftriaxone and sustained serious complications, including granulocytopenia, fever, hepatitis, and Clostridium difficile-associated diarrhea. We caution physicians to weight carefully the risks of empiric treatment for ill-defined medical problems, and to recognize the hazards of even "safe" medications.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Nadelman RB,Arlin Z,Wormser GPdoi
10.1097/00007611-199110000-00024subject
Has Abstractpub_date
1991-10-01 00:00:00pages
1263-5issue
10eissn
0038-4348issn
1541-8243journal_volume
84pub_type
杂志文章abstract::The number of breast cancer survivors has increased and this increase is expected to continue, likely as a result of population and age growth, the implementation of earlier detection strategies, and the development of more effective therapies. Breast cancer treatment requires a multidisciplinary approach with surgery...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.14423/SMJ.0000000000000701
更新日期:2017-10-01 00:00:00
abstract::With the advent and increased use of chemotherapeutic agents and radiation therapy, cancer survival rates have increased. With increased survival, both acute and chronic cardiotoxic adverse effects have emerged. The growing need for managing the treatment of individuals with chemotherapy-induced cardiotoxicity has led...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.14423/SMJ.0000000000000232
更新日期:2015-02-01 00:00:00
abstract::We prospectively studied preoperative and postoperative grip and pinch strength in 21 patients having 30 consecutive median nerve decompressions for carpal tunnel syndrome. All procedures were done by one surgeon. Each hand operated on served as its own control and was studied by the same therapist preoperatively and ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199209000-00009
更新日期:1992-09-01 00:00:00
abstract::Cyclosporine is a fungal metabolite increasingly used as an immunosuppressive agent in organ transplantation. It provides immunosuppression primarily through reversible inhibition of T-lymphocytes, without myelotoxicity. Cyclosporine appears to inhibit primary activation of helper cells and to decrease the production ...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198602000-00017
更新日期:1986-02-01 00:00:00
abstract:BACKGROUND:This study was done to determine the accuracy of the 2 x 2 cm pocket identifying low amniotic fluid (AF) volume in singleton and twin pregnancies. METHODS:The AF volume was evaluated by ultrasonography for the presence of a 2 x 2 cm pocket before amniocentesis. The actual AF volume was then determined by a ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199908000-00011
更新日期:1999-08-01 00:00:00
abstract::Squamous cell carcinoma of the cervix is a common malignancy, but like other genital malignancies, it rarely metastasizes to the heart, even in advanced stages. This case illustrates several points, including the presentation of a cardiac metastasis mimicking ischemic cardiac disease on electrocardiogram. The diagnosi...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199302000-00019
更新日期:1993-02-01 00:00:00
abstract::Fiberoptic gastrointestinal endoscopy was performed on 52 patients between the ages of 2 months and 16 years. The procedures were safely and easily done with premedications consisting of meperidine, promethazine, and chlorpromazine, and atropine, with diazepam given at the time of the procedure. Fiberoptic endoscopy w...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197805000-00022
更新日期:1978-05-01 00:00:00
abstract::We retrospectively analyzed experience with total gastrectomy (TG) for gastric carcinoma in 23 patients. The TNM stage was I in one patient, II in one patient, III in eight patients, and IV in 13. Linitis plastica was found in ten patients. The operation was considered curative in only eight patients (35%). There were...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198908000-00011
更新日期:1989-08-01 00:00:00
abstract::We have reported a case of Meige's syndrome in a middle-aged man who eventually had a cerebellar degeneration syndrome. The extrapyramidal symptoms preceded cerebellar signs and symptoms by 5 years. Most patients with idiopathic Meige's syndrome show some improvement with high-dose anticholinergic therapy. Our patient...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199103000-00019
更新日期:1991-03-01 00:00:00
abstract::A case of Wuchereria bancrofti filariasis was recently seen in a Haitian immigrant in Charleston, SC. The Caribbean area is a known endemic focus for this organism. With the increased numbers of immigrants from that area, it is likely that other such cases will be seen in the US. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198504000-00032
更新日期:1985-04-01 00:00:00
abstract::We have described a 6-day-old male infant who presented with Neisseria gonorrhoeae conjunctivitis and a scalp abscess. Delivery was complicated by rupture of the membranes 24 hours before delivery and fetal monitoring for four hours. The rare scalp abscesses caused by gonococci cleared with penicillin therapy. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198003000-00042
更新日期:1980-03-01 00:00:00
abstract::We have reported a case of suppurative pylephlebitis in an elderly, debilitated patient. The infection was caused by toothpick perforation of and migration from the gastrointestinal tract. The patient had risk factors for foreign body ingestion, including poor dentition, aphasia caused by a previous cerebrovascular ac...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198803000-00034
更新日期:1988-03-01 00:00:00
abstract::The patient we have described had lower extremity numbness, paresthesias, constipation, urinary retention, and sexual dysfunction. Laboratory evaluation confirmed a diagnosis of acute intermittent porphyria (AIP). Vitamin B6 and glucose therapy initiated resolution of symptoms. The sensory neuropathy described here is...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1991-05-01 00:00:00
abstract::Bullosis diabeticorum, or diabetic bullae, is a non-inflammatory blistering condition that is virtually diagnostic of diabetes. Diabetic bullae most often present as painless, tense, superficial bullae that occur in an acral distribution and commonly heal in 2-6 weeks without scarring, but complications such as second...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181a506d6
更新日期:2009-06-01 00:00:00
abstract::A patient with a large paraesophageal hernia had a Nissen fundoplication via laparoscopy. He returned a year later with the transverse colon herniated into the chest. At operation, the hernia ostium was found to be the aortic hiatus. We believe that the original ostium was missed because of the limited exposure of the...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199703000-00016
更新日期:1997-03-01 00:00:00
abstract::Pregnancy in patients who have non-Hodgkin's lymphoma is unusual. We have reported a case of diffuse, poorly differentiated lymphocytic lymphoma, stage IIIa, in a patient whose disease went into remission after she received six courses of CHOP therapy (cyclophosphamide, doxorubicin, vincristine, and prednisolone). She...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198510000-00032
更新日期:1985-10-01 00:00:00
abstract::Obsessive-compulsive disorder (OCD) is an intriguing, difficult problem characterized by anxiety-producing intrusive thoughts and performance of anxiety-reducing rituals. Current evidence suggests that OCD may be associated with dysregulation of serotonin and dopamine neurotransmission. Numerous early studies involvin...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199403000-00003
更新日期:1994-03-01 00:00:00
abstract:BACKGROUND:Tobacco-growing states have few tobacco control laws, which are relatively weak compared with those in non-tobacco-growing states. Region of the country has been shown to be a predictor of legislators' intentions to vote for cigarette tax increases. METHODS:A total of 116 lawmakers (84%) participated in fac...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2002-03-01 00:00:00
abstract::I reviewed the cases of 50 consecutive patients who had a total of 75 plastic surgery procedures after weight reduction. The average weight loss was 126 lb. There were 28 women and 22 men. The 75 operations were abdominoplasty (24), face-lift (18), reduction mammaplasty (ten), blepharoplasty (eight), mastopexy (eight)...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198711000-00011
更新日期:1987-11-01 00:00:00
abstract::An 86-year-old man presented with sudden onset of dyspnea during hospitalization. Initial electrocardiography (ECG) showed poor R-wave progression of precordial leads with elevation of troponin I. Tension pneumothorax was subsequently diagnosed and the ECG returned to normal after resolution of clinical compromise. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181aeda06
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND:Cluster headache (CH), though not fully characterized until this century, is a relatively common primary headache disorder. METHODS:We reviewed pertinent literature on CH and related cephalalgias. RESULTS:We found that CH typically occurs in middle-aged men and has a characteristic cyclic temporal pattern....
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199807000-00002
更新日期:1998-07-01 00:00:00
abstract::Phantom sensation and phantom limb pain are two recognized sequelae of limb amputation. In most previous surveys, amputations were done for arteriosclerotic or trauma related conditions. We studied 25 patients who had lower extremity amputation for neoplasia. In studying the features of pain before and after amputatio...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198501000-00009
更新日期:1985-01-01 00:00:00
abstract::The pronounced predilection of bronchogenic carcinoma for tuberculous lobes of the lungs is not generally recognized. In this plus 11 other series of patients with coexisting disease, an average of 52% had the neoplasm in a tuberculous lobe. In the present study, tuberculosis was confined to one or two lobes in 24 of ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197804000-00010
更新日期:1978-04-01 00:00:00
abstract::Use of the needle-catheter feeding jejunostomy at Richland Memorial Hospital and the Dorn Veterans Administration Hospital, both clinical teaching institutions of the University of South Carolina School of Medicine, has been evaluated in 114 patients ranging from 20 to 90 years old. The results of this survey span a 3...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198611000-00018
更新日期:1986-11-01 00:00:00
abstract::High fever occurred in a 30-year-old woman five weeks after transsphenoidal hypophysectomy for a pituitary adenoma. Extensive investigation failed to reveal any evidence of infection, and the clinical findings suggested the fever to be a manifestation of steroid withdrawal. Either suboptimal dosage of corticosteroid r...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198903000-00027
更新日期:1989-03-01 00:00:00
abstract:BACKGROUND:Primary care providers (PCPs) have limited training in recognizing common skin disorders, and additional emphasis may be placed on laboratory evaluation, including skin biopsies. METHODS:Primary care providers in Miami, Fla, were surveyed regarding skin biopsy and excision practices and histologic interpret...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2001-05-01 00:00:00
abstract::Elevation in fasting serum gastrin levels was found in three patients being evaluated for persistent upper abdominal pain without radiographic evidence of peptic ulcer disease. Fiberoptic endoscopy of the upper gastrointestinal tract in each patient revealed characteristic changes of chronic atrophic gastritis. Gastri...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197612000-00010
更新日期:1976-12-01 00:00:00
abstract::In response to the increasing care needs of geriatric patients and attendant hospital costs, the Nashville Veterans Administration Medical Center, which has 393 beds and admits 8400 patients annually, initiated an Intermediate Care Service in 1988. A geriatric team was formed, sharing staff and resources from existing...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1991-05-01 00:00:00
abstract:OBJECTIVES:Manifestations of gastroparesis are heterogeneous and clinical complications are poorly defined. Misconceptions of gastroparesis may be common. The objective was to determine physicians' perception of gastroparesis and identify areas that need further research and education. METHODS:A physician survey was p...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e318215fa5a
更新日期:2011-06-01 00:00:00
abstract::The diagnosis of sarcoidosis is best established when there is evidence of granulomatous involvement in two or more organs. Three patients with unusual cutaneous manifestations of sarcoidosis, including palmar and follicular lesions, nonscarring alopecia, and widespread plaque or erythrodermic sarcoidosis, are reporte...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197706000-00009
更新日期:1977-06-01 00:00:00