IgA deposits along glomerular basement membranes in rapidly progressive glomerulonephritis.

Abstract:

:This case presents a rare type of crescentic glomerulonephritis characterized as IgA deposits predominantly along the glomerular basement membranes (GBM). The patient clinically manifested with rapidly progressive glomerulonephritis (RPGN) without pulmonary hemorrhage or vasculitis-related systematic symptoms. No positive results were found on antinuclear antibody (ANA), antineutrophil cytoplasmic antibody (ANCA), or anti-GBM antibody detection. Therapy with pulse methylprednisolone and intravenous cyclophosphamide was less effective. This case does not belong to the present three categories of crescentic glomerulonephritis based on the clinical characteristics, serum test, immunofluorescence, and electron microscopic findings.

journal_name

South Med J

journal_title

Southern medical journal

authors

Cai G,Chen P,Wu D,Shi S,Yin Z,Zhang X,Wei R,Chen X

doi

10.1097/SMJ.0b013e3181817c22

subject

Has Abstract

pub_date

2008-09-01 00:00:00

pages

945-7

issue

9

eissn

0038-4348

issn

1541-8243

journal_volume

101

pub_type

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