Abstract:
:Acute gastroduodenal erosions and ulcerations, often with life-threatening gastrointestinal hemorrhage, contribute to high mortality in critically ill patients. Hypersecretion of gastric acid to some degree seems to be necessary. Antacids and recently cimetidine, a histamine H2-receptor antagonist, have been used for prophylaxis against bleeding from these acute "stress" erosions. Review of studies regarding such prophylaxis suggests that either agent may be effective, but massive life-threatening gastrointestinal hemorrhage has not been decreased by this therapy, and, more important, there has not been an increased survival in treated patients. Furthermore, cimetidine is not approved for such use by the FDA. Currently, in critically ill patients there are multiple risk factors for acute "stress" erosions. An intensive antacid regimen may be impractical. Alternatively, cimetidine may be given as an investigational drug. Further studies are needed on the efficacy of antacids and cimetidine in preventing acute "stress" erosion and bleeding, but such studies should be prospective, controlled, double-blind, stratified, and randomized to produce the most useful data.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Luk GDdoi
10.1097/00007611-198004000-00007subject
Has Abstractpub_date
1980-04-01 00:00:00pages
424-6issue
4eissn
0038-4348issn
1541-8243journal_volume
73pub_type
杂志文章abstract::Chronic mucocutaneous candidiasis is a heterogeneous group of immunodeficiencies associated with persistent candidal infections. Patients with chronic mucocutaneous candidiasis are rarely associated with systemic infections caused by other fungi, but almost never by Candida. The authors report a case of a 16-year-old ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-200408000-00024
更新日期:2004-08-01 00:00:00
abstract:OBJECTIVES:Studies have shown that the overutilization of laboratory tests ("labs") for hospitalized patients is common and can cause adverse health outcomes. Our objective was to compare the ordering tendencies for routine complete blood counts (CBC) and chemistry panels by internal medicine residents and hospitalists...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000592
更新日期:2017-01-01 00:00:00
abstract::We have described a class 4 choledochal cyst in a 24-year-old black woman treated with choledochocystoduodenostomy. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198605000-00034
更新日期:1986-05-01 00:00:00
abstract::Forty consecutive patients having left ventricular (LV) aneurysmectomy were evaluated for surgical risk predictors and were then followed up after operation. Factors evaluated included age, time since last myocardial infarction, NYHA classification, principal indication for surgery, LV end diastolic pressure, LV "A" w...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198005000-00018
更新日期:1980-05-01 00:00:00
abstract:OBJECTIVES:The objective of this study was to assess the cardiovascular health status of baby boomers with diabetes mellitus (DM) in comparison to the same-age population with DM 10 years previously. METHODS:The study was conducted in baby boomers with DM using data from the National Health and Nutrition Examination S...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000473
更新日期:2016-06-01 00:00:00
abstract:OBJECTIVES:To determine the documentation frequency of informed consent for women undergoing a trial of nonemergent instrumental delivery. STUDY DESIGN:A retrospective chart review of instrumented vaginal deliveries from 1992 to 2005 was performed. Cases were identified from a Labor and Delivery database and hospital ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.smj.0000243076.86803.09
更新日期:2006-12-01 00:00:00
abstract::While fish consumption is considered a component of a heart-healthy diet, many illnesses have been associated with eating contaminated fish. The authors describe two cases of muscle weakness and rhabdomyolysis that occurred after eating salmon. Cases of rhabdomyolysis and muscle weakness after consumption of fresh wat...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181583673
更新日期:2007-11-01 00:00:00
abstract::We measured hemodynamic and respiratory parameters before and after applying methylmethacrylate (MMC) to acetabular and femoral sites during neuroleptanesthesia and prosthetic hip surgery. No significant major changes were documented. Previously reported adverse effects probably have been due to medullary emboli, humo...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198110000-00013
更新日期:1981-10-01 00:00:00
abstract::Atypical facial pain or neuralgia and lower-half headache are confusing terms and should be discarded. Recurrent unilateral, throbbing, frontal headaches should be referred to as facial migraine. Patients whose trigeminal branches have been subjected to repeated surgical procedures and who have relentless unilateral f...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198207000-00012
更新日期:1982-07-01 00:00:00
abstract::Proximal gastric vagotomy is a useful operation for duodenal ulcer disease that is intractable to medical management. It is also useful in selected patients with acute duodenal ulcer perforation. We present an overview of the indications for proximal gastric vagotomy, along with its results. The major benefits of prox...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-198906000-00014
更新日期:1989-06-01 00:00:00
abstract::Human ehrlichiosis is a tick-borne rickettsial disease characterized by fever, headache, myalgias, anorexia, and occasionally rash. In our patient, changes in mental status, upper motor neuron signs, cerebrospinal fluid pleocytosis, and increased serum protein levels were found in association with serologically confir...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199011000-00031
更新日期:1990-11-01 00:00:00
abstract::Optimal antimicrobial therapy for viridans streptococcal endocarditis remains controversial. Rifampin was bactericidal at less than 0.2 micrograms/ml for ten strains of viridans streptococci isolated from patients with endocarditis. Administration of rifampin to one endocarditis patient already receiving penicillin an...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198308000-00005
更新日期:1983-08-01 00:00:00
abstract:BACKGROUND:Tobacco use causes significant morbidity and mortality. Resident physicians at the George Washington University Medical Center are trained to counsel patients to stop smoking. METHODS:I retrospectively reviewed charts of 300 patients treated by resident physicians in the Department of Medicine (200) and the...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199910000-00007
更新日期:1999-10-01 00:00:00
abstract::In 98 patients, we cannulated the subclavian and internal jugular veins with modified Shaldon catheters, using the Seldinger technic. Catheters were left for long periods, and multiple dialyses were accomplished with each catheter. The incidence of major complications was less than 5%. None of the catheters were belie...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198209000-00016
更新日期:1982-09-01 00:00:00
abstract::Potentially serious iatrogenic hand injuries occurred in three patients in a general medicine practice. All resulted from technologic advances in patient care. Each resulted in substantial economic and emotional costs. One patient sustained a serious residual disability. Such injuries have rarely been reported in the ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198612000-00011
更新日期:1986-12-01 00:00:00
abstract::We have reported a case of Campylobacter osteomyelitis, which we believe has not been previously reported. Symptoms and signs were nonspecific, but darkfield microscopy of a suspension of isolated bacteria was useful in making a presumptive diagnosis. Initial parenteral therapy based on sensitivity testing and prolong...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198412000-00044
更新日期:1984-12-01 00:00:00
abstract::Five patients with Barrett's esophagus, each with a differing presentation, serve as the basis of this report. Hiatal hernia is noted to be frequently present in Barrett's esophagus, and the incidence of adenocarcinoma is thought to be distinctly increased. The condition is easily diagnosed by fiberoptic endoscopy and...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1976-03-01 00:00:00
abstract::Psychiatric hospital services for adolescents have steadily increased in recent years and great interest has been generated in determining treatment outcome. In this study, 74 adolescent inpatients completed structured telephone interviews one year after discharge. The questions probed school, job, and family adjustme...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198009000-00013
更新日期:1980-09-01 00:00:00
abstract::The application of 70% helium-30% oxygen mixtures by tight-fitting face mask in the emergency management of large airway obstruction is well known. We present the case of an infant with severe large airway obstruction and respiratory failure that was unresponsive to the more traditional approaches of airway management...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1991-05-01 00:00:00
abstract::Carcinoma of the fallopian tube is the least common of the gynecologic malignancies. Because of its rarity and the absence of typical symptoms, preoperative diagnosis is seldom made. Patient as well as physician delay in diagnosis is often considerable. There are no reliable laboratory aids available to enhance the di...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197509000-00021
更新日期:1975-09-01 00:00:00
abstract:BACKGROUND:Remodeling of the endocrine pancreas, caused by the deleterious effects of amylin as it is co-synthesized, co-packaged, and co-secreted with insulin, gives clinicians and researchers cause to ponder. METHODS:A literature search was done, and relevant publications and texts on amylin and islet amyloid polype...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Insulin resistance is characterized by impaired responsiveness to endogenous or exogenous insulin. Loss of responsiveness is associated with a "clustering" of cardiovascular risk factors that includes abdominal obesity, hypertension, dyslipidemia, glucose intolerance, and hyperinsulinemia; this association i...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199901000-00002
更新日期:1999-01-01 00:00:00
abstract::A case of nephrotic syndrome due to minimal change renal disease was associated with minimally symptomatic nodular sclerosing Hodgkin's disease in a 15-year-old girl. Although minimal renal disease is the most frequently described biopsy finding in this paraneoplastic syndrome, the combination of nodular sclerosing Ho...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198205000-00027
更新日期:1982-05-01 00:00:00
abstract::Using continuous wave Doppler ultrasound, we studied the umbilical and uterine flow velocity waveforms in 68 pregnant women who had chronic hypertension and/or preeclampsia. The systolic-diastolic (S/D) ratio was considered an expression of vascular resistance peripheral to the point of insonation. Abnormal umbilical ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199002000-00005
更新日期:1990-02-01 00:00:00
abstract::We describe a 47-year-old man with shoulder pain, multiple bony lesions, and a 1-cm lesion in the spleen. T-1 facetectomy revealed a poorly differentiated malignant neoplasm. Several months after chemotherapy, multiple splenic lesions were found by computed tomography and liver-spleen scan. A splenectomy showed a mali...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199508000-00020
更新日期:1995-08-01 00:00:00
abstract::Narcolepsy is a severely debilitating neurologic disease that is not as rare as many believe, affecting an estimated 140,000 Americans. Despite the sometimes debilitating nature of narcolepsy symptoms, the disease may go undiagnosed without an organized method for evaluating patients with sleep complaints. Many of the...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/01.smj.0000056655.15660.42
更新日期:2003-03-01 00:00:00
abstract::We present a case believed to be the first reported North American presentation of Ascaris lumbricoides within the urogenital tract. A young man came to the emergency department because of painless hematuria and having observed a 6-inch worm exit his urethra while urinating. The most common site for A lumbricoides inf...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2001-04-01 00:00:00
abstract:OBJECTIVES:Inclusion of select orthopedic problems in the orthopedics observation unit (OOU) may reduce hospital admissions. Our system allows OOU status for 24 hours, but the effect on admissions is unknown. Our primary hypothesis was that we could predict which OOU patients required admission based on the presence of...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000181
更新日期:2014-10-01 00:00:00
abstract::Mycobacterium fortuitum is a rare, opportunistic pathogen most frequently contracted through contact with a contaminated source. An immunocompetent 26-year-old female patient presented to our institution with an infected lumboperitoneal (LP) shunt presenting as continued nonhealing wounds. After multiple debridements,...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000955
更新日期:2019-04-01 00:00:00
abstract::Unremitting diarrhea is a common problem in patients with AIDS. We have reported the case of such a patient who was treated with the somatostatin analogue octreotide for chronic diarrhea and who had acute pancreatitis as a consequence of this therapy. We postulate that the possible mechanism for the pathogenesis of th...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199111000-00035
更新日期:1991-11-01 00:00:00