Primary angiosarcoma of the spleen: a case report and review of the literature.

Abstract:

:We describe a 47-year-old man with shoulder pain, multiple bony lesions, and a 1-cm lesion in the spleen. T-1 facetectomy revealed a poorly differentiated malignant neoplasm. Several months after chemotherapy, multiple splenic lesions were found by computed tomography and liver-spleen scan. A splenectomy showed a malignant spindle-cell neoplasm forming irregular vascular spaces. Tumor cells were positive for factor VIII-related antigen and vimentin. This patient died of extensive metastases from this primary angiosarcoma of the spleen. Splenic angiosarcoma is a rare neoplasm that often has a cryptic presentation and a dismal prognosis.

journal_name

South Med J

journal_title

Southern medical journal

authors

McGinley K,Googe P,Hanna W,Bell J

doi

10.1097/00007611-199508000-00020

subject

Has Abstract

pub_date

1995-08-01 00:00:00

pages

873-5

issue

8

eissn

0038-4348

issn

1541-8243

journal_volume

88

pub_type

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