Successful moxalactam therapy for gram-negative bacillary meningitis in neonates.

Abstract:

:Three neonates with gram-negative bacillary meningitis were treated with moxalactam after therapy with ampicillin plus aminoglycoside, trimethoprim-sulfamethoxazole, or chloramphenicol failed to sterilize the CSF. Clinical improvement and CSF sterility occurred after therapy with moxalactam was initiated. Moxalactam concentrations in CSF exceeded MICs of each organism. All three patients were cured of their infection. Moxalactam appears to be an effective antibiotic for the treatment of neonatal gram-negative bacillary meningitis.

journal_name

South Med J

journal_title

Southern medical journal

authors

Ramos OM,Kaplan SL,Mason EO Jr,Denson S,Pickering LK

doi

10.1097/00007611-198205000-00040

subject

Has Abstract

pub_date

1982-05-01 00:00:00

pages

632-3

issue

5

eissn

0038-4348

issn

1541-8243

journal_volume

75

pub_type

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