Thrombolysis in acute pulmonary thromboembolism.

Abstract:

: Acute pulmonary embolism (PE) is a common clinical condition with presentations that may vary from asymptomatic subsegmental emboli to massive vascular obstruction and shock with high risk of death. Identifying patients at highest risk for death is critical to select those who would benefit most from thrombolytic therapy. New and evolving clinical prediction models, serum tests, and imaging modalities are being used to improve our ability to identify potential thrombolytic candidates. We review the evolution of the present guidelines on the management of PE, specifically regarding the evolving role of thrombolytics; outcomes following thrombolytic therapy, including mortality, hemorrhage, hemodynamic improvement, and prevention of chronic thromboembolic pulmonary hypertension; and our strategy for risk stratification of pulmonary embolism.

journal_name

South Med J

journal_title

Southern medical journal

authors

Vyas PA,Donato AA

doi

10.1097/SMJ.0b013e318268dbca

subject

Has Abstract

pub_date

2012-10-01 00:00:00

pages

560-70

issue

10

eissn

0038-4348

issn

1541-8243

pii

00007611-201210000-00015

journal_volume

105

pub_type

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