Abstract:
BACKGROUND:Several previous studies of invasive Group A streptococcal (GAS) disease have been hindered by small sample sizes (< or = 100 patients) and limited generalizability. METHODS:We conducted a population-based study of invasive GAS disease. The objectives of the study were to describe the clinical features of individuals who were hospitalized for invasive GAS disease and to identify risk factors for hospital mortality. The cases were 257 patients who were hospitalized throughout Florida during a 4-year period and reported to the Florida Department of Health. Logistic regression was used to calculate adjusted odds ratios (OR) for mortality and 95% confidence intervals (CI). RESULTS:The overall mortality was 18% (41 of 228). Admission into an intensive care unit was a strong predictor of mortality (OR, 20.41; 95% CI, 6.41-64.96). Treatment with clindamycin reduced mortality in patients who had necrotizing fasciitis (OR, 0.11; 95% CI, 0.01-0.89) but not in patients who did not have necrotizing fasciitis (OR, 1.01; 95% CI, 0.31-3.33). CONCLUSION:Clindamycin reduces mortality in patients with invasive GAS disease who have necrotizing fasciitis.
journal_name
South Med Jjournal_title
Southern medical journalauthors
Mulla ZD,Leaverton PE,Wiersma STdoi
10.1097/01.SMJ.0000051060.95210.9Asubject
Has Abstractpub_date
2003-10-01 00:00:00pages
968-73issue
10eissn
0038-4348issn
1541-8243journal_volume
96pub_type
杂志文章abstract:BACKGROUND:Cluster headache (CH), though not fully characterized until this century, is a relatively common primary headache disorder. METHODS:We reviewed pertinent literature on CH and related cephalalgias. RESULTS:We found that CH typically occurs in middle-aged men and has a characteristic cyclic temporal pattern....
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/00007611-199807000-00002
更新日期:1998-07-01 00:00:00
abstract::Cardiac ascites is a rare condition. Diagnosis is aided by liver histology, which characteristically shows diffuse hepatic congestion affecting the centrilobular region. In our case of refractory ascites due to constrictive pericarditis, diagnosis was delayed because centribular hepatic congestion was absent histologi...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199211000-00023
更新日期:1992-11-01 00:00:00
abstract::Guar gum is a high polymer carbohydrate that undergoes considerable expansion and thickening when placed in water. Because of this property, guar gum has been used in "weight loss" tablets marketed by several pharmaceutical manufacturers. These tablets undergo expansion in the stomach and are expected to cause early s...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199206000-00015
更新日期:1992-06-01 00:00:00
abstract::Pregnancy in patients who have non-Hodgkin's lymphoma is unusual. We have reported a case of diffuse, poorly differentiated lymphocytic lymphoma, stage IIIa, in a patient whose disease went into remission after she received six courses of CHOP therapy (cyclophosphamide, doxorubicin, vincristine, and prednisolone). She...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198510000-00032
更新日期:1985-10-01 00:00:00
abstract::The experience of the Southern Regional Trophoblastic Disease Center includes 222 patients who were referred from January 1972 to October 1977. The initial tissue diagnosis was hydatidiform mole in 212 patients and choriocarcinoma in ten. There was spontaneous remission of 142 (69%) of the moles and one of the chorioc...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197811000-00006
更新日期:1978-11-01 00:00:00
abstract::A 37-year-old black man with presumed Pneumocystis carinii pneumonia who was treated with systemic IV pentamidine had fatal pancreatitis and massive hepatomegaly. Fatal pancreatitis can occur with no hemorrhagic changes seen at autopsy. Awareness of the relationship between pentamidine and pancreatitis should be empha...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1991-06-01 00:00:00
abstract::Acute gastroduodenal erosions and ulcerations, often with life-threatening gastrointestinal hemorrhage, contribute to high mortality in critically ill patients. Hypersecretion of gastric acid to some degree seems to be necessary. Antacids and recently cimetidine, a histamine H2-receptor antagonist, have been used for ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198004000-00007
更新日期:1980-04-01 00:00:00
abstract::Pyridium (phenazopyridine hydrochloride) is often prescribed as an analgesic in patients following trauma, surgery, or infections of the urinary tract. Pyridium toxicity has been previously reported, however, most cases result in a single adverse effect. Herein the authors describe an elderly patient who presented wit...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/01.smj.0000197299.77949.16
更新日期:2006-01-01 00:00:00
abstract::Early gradual ambulation is currently recommended for patients with acute low back pain if results of neurologic examination are normal. Bed rest for up to 2 days is considered optimal. To assess management practices, we retrospectively reviewed the medical records of individuals with acute back pain treated at three ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1991-05-01 00:00:00
abstract:OBJECTIVE:Our study aimed to investigate the association between maternal-perceived psychological stress and fetal telomere length. METHODS:We recruited women in labor upon hospital delivery admission. Based on responses to the Perceived Stress Scale, we categorized participants as having "high," "normal," or "low" pe...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000567
更新日期:2016-12-01 00:00:00
abstract:OBJECTIVES:Total annual costs for syncope-related hospitalizations were $2.4 billion in 2000. The aim of this study was to examine the type and number of tests ordered for patients admitted with syncope and whether these tests helped establish the cause. METHODS:We studied the records of 1038 patients coded as "syncop...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000184
更新日期:2014-11-01 00:00:00
abstract::The clinical presentations of liver abscess, hepatoma, and metastatic tumor to the liver may be quite similar, and procedures such as computerized tomography, radionuclide scanning, and ultrasonography of the liver cannot make a specific diagnosis. Therefore, we compared the clinical presentations of 38 patients seen ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198712000-00013
更新日期:1987-12-01 00:00:00
abstract::Myxoma is the most common primary tumor of the heart. The typical presentations include a triad of embolic phenomena, intracardiac flow obstruction, and constitutional symptoms. We report a case of cardiac myxoma presenting as prolonged fever. Leukocytosis with a left shift, anemia, and elevated C-reactive protein wer...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3182142bbd
更新日期:2011-05-01 00:00:00
abstract::Slipped capital femoral epiphysis has been described in several syndromes associated with short stature and endocrine disturbances. I have presented a case of slipped capital femoral epiphysis in conjunction with Russell-Silver syndrome. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198907000-00026
更新日期:1989-07-01 00:00:00
abstract::Innovar, administered intramuscularly 45 minutes preoperatively, provides excellent operative sedation, analgesia, and patient cooperation. Postoperative complications are minimized, and the quantity of postoperative analgesics and antiemetics is drastically reduced when Innovar is used as a preoperative medication. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197511000-00020
更新日期:1975-11-01 00:00:00
abstract::The results of radiation therapy of 79 patients with early carcinoma of the vocal cord are reported. Nine (13%) of the 69 patients with stage I disease had local recurrence, and two (20%) of the ten patients with stage II disease had local recurrence without local node metastasis. Subsequent control of radiation failu...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197901000-00004
更新日期:1979-01-01 00:00:00
abstract::This is a case which highlights unique diagnostic challenges in the evaluation of a previously healthy patient presenting with a myelopathy initially most concerning for malignancy. However, timely recognition and nonoperative therapy of unexpected spinal sarcoidosis with corticosteroidal therapy was crucial in averti...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/SMJ.0b013e3181e90745
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND:To design and evaluate interventions for reducing the impact of stroke in Georgia, we assessed knowledge of signs, risk factors, and burden of stroke. METHODS:Adults in Georgia were studied with a random digit dial telephone survey. RESULTS:Answering an unaided question, 39% of 602 respondents named > or =...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:2001-06-01 00:00:00
abstract::Any terrorist attack using weapons of mass destruction will result in substantial psychological trauma and stress. Primary care and emergency clinics will likely see patients who have stress-related emotional or physical symptoms, or exacerbations of preexisting health concerns. Significant psychological and behaviora...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/01.SMJ.0000054783.69453.79
更新日期:2003-04-01 00:00:00
abstract::The incidence of acute rheumatic fever in Mississippi was estimated by reviewing the hospital charts of Mississippi residents with a discharge diagnosis of acute rheumatic fever from 1964 through 1973. The average annual incidence was 1.5 cases/100,000 population for primary attacks and 0.4 cases/100,000 population fo...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-198105000-00013
更新日期:1981-05-01 00:00:00
abstract::Cantharidin in either a 0.9% or 0.7% solution is a safe and effective office treatment for molluscum contagiosum. It simplifies the treatment, especially of children, by being a quick, simple, and painless procedure, but it should be applied only by the physician. ...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1979-08-01 00:00:00
abstract:BACKGROUND:Smokeless tobacco (ST) use is associated with significant health risks and is increasing in prevalence in the United States. This study examined the prevalence of ST use among patients seen in two family practice centers and the documentation of that ST use in the medical record. METHODS:A survey of 209 pat...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199712000-00012
更新日期:1997-12-01 00:00:00
abstract::Results in three series of spinal fusions with Harrington instrumentation for scoliosis were compared. Patient ages ranged from 9 to 22 years, and follow-up from 12 to 105 months. Cylindrical inlay facet grafting was done in all cases. Supplemental heterologous bone was used in the first series of 51 cases, autologous...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-197702000-00025
更新日期:1977-02-01 00:00:00
abstract::Parameters for significant risk of aspiration have been defined as a gastric pH less than 2.5 and/or a volume greater than 25 ml. We investigated the effects of metoclopramide and cimetidine, alone and in combination, on the pH and volume of gastric contents of patients taking nothing by mouth before general anesthesi...
journal_title:Southern medical journal
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00007611-198611000-00009
更新日期:1986-11-01 00:00:00
abstract:OBJECTIVES:A small but significant number of patients make frequent emergency department (ED) visits to multiple EDs within a region. We have a unique health information exchange (HIE) that includes every ED encounter in all hospital systems in our region. Using our HIE we were able to characterize all frequent ED user...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000488
更新日期:2016-07-01 00:00:00
abstract::We report the case of an 18-year old man with hemolytic-uremic syndrome (HUS) having a classic clinical presentation and diagnostic renal pathology without evidence of microangiopathic hemolytic anemia (MAHA) by peripheral blood smear. Indirect evidence of hemolysis was suggested by mild anemia, elevation of serum lac...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199603000-00018
更新日期:1996-03-01 00:00:00
abstract::The renin-angiotensin-aldosterone system (RAAS) plays a major role in blood pressure regulation and is thus an important therapeutic target in the management of hypertension. Angiotensin receptor blockers (ARBs), which interrupt RAAS overactivity by blocking a specific receptor that mediates the pathogenic activity of...
journal_title:Southern medical journal
pub_type: 杂志文章,评审
doi:10.1097/SMJ.0b013e3181e1e2da
更新日期:2010-07-01 00:00:00
abstract:OBJECTIVES:Osteopenia is considerably more common than osteoporosis and accounts for most of the fracture burden in women older than 50 years. It is uncertain when to initiate treatment in osteopenia. We sought to determine in women with osteopenia what effect transitioning to lower categories had on subsequent fractur...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.14423/SMJ.0000000000000410
更新日期:2016-02-01 00:00:00
abstract::The application of 70% helium-30% oxygen mixtures by tight-fitting face mask in the emergency management of large airway obstruction is well known. We present the case of an infant with severe large airway obstruction and respiratory failure that was unresponsive to the more traditional approaches of airway management...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:
更新日期:1991-05-01 00:00:00
abstract::A marked increase in the number of cases of shigellosis was reported in Kentucky in 1988. To examine reasons for this increase, we reviewed the 389 cases of shigellosis reported from 1986 through 1989. Ninety-three percent (285/305) of cases due to known species were due to Shigella sonnei. Sixty-two percent (243/389)...
journal_title:Southern medical journal
pub_type: 杂志文章
doi:10.1097/00007611-199107000-00002
更新日期:1991-07-01 00:00:00