Antiretroviral treatment leading to secondary trimethylaminuria: Genetic associations and successful management with riboflavin.

abstract：BACKGROUND:Although they originated from China, Malays have undergone a lot of intermarriages. A study suggested that CYP2D6 poor metabolism (PM) phenotype was more common in Malays compared to Chinese. CYP2D6 is highly polymorphic and is involved in the metabolism of many drugs and has been implicated in some environm...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Ismail R,Hussein A,Teh LK,Nizam Isa M

更新日期：2000-10-01 00:00:00

abstract：:When designing studies of the optimal use of antimicrobial drugs, it is important to define at an early stage, which outcome parameters to use. It must be clear to which category a parameter to be measured belongs: the structure, the process or a clinical outcome. Attention must be paid to the measurement scales as we...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Natsch S,Kullberg BJ,Hekster YA,van der Meer JW

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:Emerging antibiotic resistance in common pathogens is a worldwide problem known to be related to inappropriate overuse of antibiotics. Wide variability in antibiotic use throughout the world is because of various factors, including socio-cultural differences. OBJECTIVE:To study the rate of antibiotic prescr...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Kumar R,Indira K,Rizvi A,Rizvi T,Jeyaseelan L

更新日期：2008-12-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Low-dose methotrexate (LDMTX) has been widely used for many decades in clinical settings, with good safety profiles compared with those of high-dose methotrexate. LDMTX is also used as one of the off-label conservative therapies in treating placenta accreta (PA). Until now, only a few mild a...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Tan Z,Liu W,Guo H,Hu K,Zhao R

更新日期：2020-02-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Ceftriaxone is a third-generation cephalosporin with broad-spectrum antibacterial activity. Ceftriaxone-associated urolithiasis and post-renal acute renal failure (PARF) in adults is exceedingly rare and perhaps underappreciated. We report one such case to increase appreciation of this risk ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Shen-Hua W,Fan-Yi M,Qing-Ling Z,Li-Na Z,Li-Jun M

更新日期：2016-06-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Limited data are available on co-administration of acenocoumarol with direct-acting antiviral agents for chronic hepatitis C virus infection. CASE SUMMARY:We report a case of a patient who required a significant increase in acenocoumarol weekly dose probably due to an interaction with ombit...

journal_title：Journal of clinical pharmacy and therapeutics

authors： de Lorenzo-Pinto A,Giménez-Manzorro Á,Rodríguez-González CG,Ahumada-Jiménez A,Herranz-Alonso A,Marzal-Alfaro MB,Sanjurjo-Sáez M

更新日期：2016-08-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Massive acute arsenic poisoning is rare yet potentially life-threatening. 2,3-dimercaptopropane-1-sulphonate (DMPS) appears to have the appropriate chelating property. However, clinical experience on the use of DMPS in massive arsenic poisoning is limited. CASE DESCRIPTION:A 37-year-old wom...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Lu PH,Tseng JC,Chen CK,Chen CH

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:A pain relief score 50% of the maximum is often used as a clinically meaningful outcome in meta-analyses of analgesic trials. This arbitrary value requires validation. OBJECTIVE:To determine the optimum pain relief score for predicting pain relief sufficient to obviate the need for analgesic remedication in...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Li Wan Po A,Petersen B

更新日期：2006-04-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Increasing reports of the combined use of vancomycin (VAN) and piperacillin/tazobactam leading to higher nephrotoxicity have led to carbapenems being recommended as an alternative option to combine with VAN when nephrotoxicity is a major concern. However, whether carbapenems also increase th...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Zhang T,Cheng H,Li Y,Dong YZ,Zhang Y,Cheng XL,Wang AM,Dong YL

更新日期：2019-06-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Fluconazole is an antifungal agent that is commonly used to treat patients with serious systemic fungal infections in intensive care units. Fosfluconazole is a phosphate prodrug of fluconazole, which was developed to reduce the volume of fluid required to administer fluconazole by intravenou...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Aoyama T,Hirata K,Hirata R,Yamazaki H,Yamamoto Y,Hayashi H,Matsumoto Y

更新日期：2012-06-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Psoriatic arthritis is an autoimmune disease characterized by chronic inflammation of the skin and joints. Anti-TNF drugs reduce the severity of the disease in the long term. This study compares the efficacy and safety of adalimumab, etanercept, infliximab and golimumab in patients with psor...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Fénix-Caballero S,Alegre-del Rey EJ,Castaño-Lara R,Puigventós-Latorre F,Borrero-Rubio JM,López-Vallejo JF

更新日期：2013-08-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVES:To date, no case of headache has been reported with enoxaparin. We present the case of a 60-years-old man, who developed enoxaparin-induced throbbing headache and discuss the possible pharmacological mechanisms. We provide an analysis of enoxaparin-induced headache in three international da...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Brusadelli T,Carnovale C,Gentili M,Borsadoli C,Speziali A,Perrone V,Pellegrino P,Antoniazzi S,Pozzi M,Radice S,Clementi E

更新日期：2015-06-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Admixtures of levobupivacaine, fentanyl and epinephrine are increasingly used in epidural pain management. Neither the compatibility nor the stability of levobupivacaine with fentanyl and epinephrine is known and therefore we examined the chemical, physical and microbiological stability of l...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Helin-Tanninen M,Lehtonen M,Naaranlahti T,Venäläinen T,Pentikäinen J,Laatikainen A,Kokki H

更新日期：2013-04-01 00:00:00

abstract：:The primary aim of this study was to assess patterns of prescribing of analgesic medications in a primary care setting in South Africa. Medication records of 47,103 patients for the year 1995 were retrospectively reviewed. Analgesic agents represented 12.3% of the total number and 14.2% of the total cost of all the pr...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Truter I

更新日期：1997-02-01 00:00:00

abstract：OBJECTIVE:There is a growing interest in investigating the role of glutamate receptors in the pathophysiology of schizophrenia. Indeed, the hyperdopaminergic theory of schizophrenia can explain only the positive symptoms of schizophrenia, whereas the glutamate hypothesis may provide a more comprehensive view of the ill...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Noorbala AA,Akhondzadeh S,Davari-Ashtiani R,Amini-Nooshabadi H

更新日期：1999-10-01 00:00:00

abstract：:The efficacy of a novel, proprietary topical formulation of ibuprofen 5% gel (Ibugel) and ibuprofen 400 mg tablets (1200 mg daily) was compared in a double-blind, double-dummy, parallel group study in patients with acute soft tissue injuries. Patients received either active gel plus placebo tablets (n = 50) or active ...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Whitefield M,O'Kane CJ,Anderson S

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVES:Assessment of mean 24 h oestradiol (E2) and oestrone (E1) concentration and basic FSH secretion in postmenopausal asthmatic women, before and after HRT use, and to identify any connections between changes in hormone concentrations and patients' clinical state. SUBJECTS:Postmenopausal women (55 asthmatic and...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Kos-Kudła B,Ostrowska Z,Marek B,Ciesielska-Kopacz N,Sieminska L,Kajdaniuk D,Nowak M,Kudla M

更新日期：2000-12-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:There is much controversy over how angiotensin II receptor blockers (ARB) or angiotensin-converting enzyme inhibitors (ACEI) affect blood uric acid levels. Though ARB is not used to lorcwer the uric acid concentration in the blood, losartan, one of the ARB series, is known to reduce the uric...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Kim HS,Kim H,Lee SH,Kim JH

更新日期：2020-12-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Adherence to evidence-based drug therapy after acute myocardial infarction has increased over the last decades, but is still unsatisfactory. Our objectives are to set out to analyse patterns of evidence-based drug therapy after acute myocardial infarction (AMI), and evaluating socio-demograp...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Kirchmayer U,Agabiti N,Belleudi V,Davoli M,Fusco D,Stafoggia M,Arcà M,Barone AP,Perucci CA

更新日期：2012-02-01 00:00:00

abstract：WHAT IS KNOWN:The increased risk of cardiovascular events in diabetic patients has been related to numerous metabolic and haemoreological factors. Some of these factors appear to be particularly evident during the post-prandial phases and to be related to peak plasma glucose level. AIM:To compare the effect of additio...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Derosa G,Mereu R,D'Angelo A,Salvadeo SA,Ferrari I,Fogari E,Gravina A,Palumbo I,Maffioli P,Randazzo S,Cicero AF

更新日期：2010-10-01 00:00:00

abstract：:Standard meta-analytical and pharmacoeconomic techniques were used to study the clinical effectiveness and the cost-effectiveness ratio of the prophylactic (or pre-emptive) administration of G-CSF to patients with small cell lung cancer treated with conventional myelosuppressive cytotoxic chemotherapy. In the first pa...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Messori A,Trippoli S,Tendi E

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:In September 1998, legislation was introduced in the United Kingdom to limit paracetamol pack sizes to 16 tablets of 500 mg at general sales outlets and 32 tablets of 500 mg at pharmacies. The effect of the regulations on severity of paracetamol poisoning is unclear. The aim of this study was t...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Morgan O,Hawkins L,Edwards N,Dargan P

更新日期：2007-10-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Polypharmacy has a significant impact on patients' health with overall expenditure on over-the-counter (OTC) medicines representing a substantial burden in terms of cost of treatment. The aim of this study, which was conducted within the framework of a European Project funded by the European...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Kamekis A,Bertsias A,Moschandreas J,Petelos E,Papadakaki M,Tsiantou V,Saridaki A,Symvoulakis EK,Souliotis K,Papadakis N,Faresjö T,Faresjö A,Martinez L,Agius D,Uncu Y,Sengezer T,Samoutis G,Vlcek J,Abasaeed A,Merkouri

更新日期：2018-02-01 00:00:00

abstract：OBJECTIVE:To determine whether any demographic or socioeconomic factors affect the use of smoking cessation medications in patients hospitalized with heart disease. METHOD:Data were obtained from the Improving Cardiovascular Outcomes in Nova Scotia (ICONS) Canada database, which includes a registry of all hospitalized...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Whelan AM,Cooke CA,Sketris IS

更新日期：2005-04-01 00:00:00

abstract：:In many countries, including The Netherlands, little is known about the overall prescribing patterns within hospitals. While individual hospitals have some data available, these are not pooled on a regional or national level. The available data consist of dispensing data that are neither patient-linked nor diagnosis-l...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Denig P,Haaijer-Ruskamp FM,Versluis A,Wesseling H

更新日期：1991-12-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Chromium is an essential mineral for carbohydrate and lipid metabolism. Results of previous systematic reviews and meta-analyses of chromium supplementation and metabolic profiles in diabetes have been inconsistent. Recently, several published trials have emerged. We conducted a systematic r...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Suksomboon N,Poolsup N,Yuwanakorn A

更新日期：2014-06-01 00:00:00

abstract：:Although acetylsalicylic acid is prescribed for a broad range of diseases, it can induce a wide array of clinically recognized hypersensitivity reactions, including aspirin-intolerant asthma (AIA) with rhinitis and aspirin-intolerant urticaria (AIU) with anaphylaxis. Altered eicosanoid metabolism is the generally acce...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Palikhe NS,Kim SH,Park HS

更新日期：2008-10-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Lemierre's syndrome is often misdiagnosed as a common cold or viral infection. Fusobacterium necrophorum is the most common causative organism. The recommended treatment regimen is 6 weeks of a beta-lactam antibiotic along with metronidazole. CASE DESCRIPTION:We present two cases of Lemierr...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Le C,Gennaro D,Marshall D,Alaev O,Bryan A,Gelfman A,Wang Z

更新日期：2019-02-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:Teneligliptin is a DPP-4 inhibitor used for the treatment of type 2 diabetes mellitus, commonly prescribed in combination with glimepiride. Teneligliptin is metabolized by CYP3A4, and glimepiride might be partly metabolized by CYP3A4. The aim of the study was to investigate the possible effe...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Park JW,Kim KA,Choi YJ,Yoon SH,Park JY

更新日期：2019-10-01 00:00:00

abstract：WHAT IS KNOWN AND OBJECTIVE:6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone (ciclopirox) and specifically its olamine salt 6-cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridone 2-aminoethanol salt (ciclopirox olamine) are anti-fungal agents currently used for the treatment of mild to moderate cutaneous fungal infection. Our ob...

journal_title：Journal of clinical pharmacy and therapeutics

authors： Weir SJ,Patton L,Castle K,Rajewski L,Kasper J,Schimmer AD

更新日期：2011-04-01 00:00:00