Lemierre's syndrome: One rare disease-Two case studies.

Abstract:

WHAT IS KNOWN AND OBJECTIVE:Lemierre's syndrome is often misdiagnosed as a common cold or viral infection. Fusobacterium necrophorum is the most common causative organism. The recommended treatment regimen is 6 weeks of a beta-lactam antibiotic along with metronidazole. CASE DESCRIPTION:We present two cases of Lemierre's syndrome with internal jugular vein thrombophlebitis and positive blood cultures for F. necrophorum. The first case was successfully treated with 6 weeks of a beta-lactam antibiotic and 4 weeks of metronidazole, while the second case was successfully treated with 4 weeks of a beta-lactam antibiotic and 2 weeks of metronidazole. WHAT IS NEW AND CONCLUSION:Two cases of Lemierre's syndrome were treated successfully with only 2-4 weeks of metronidazole therapy. Shorter duration of metronidazole therapy should be explored in future studies.

journal_name

J Clin Pharm Ther

authors

Le C,Gennaro D,Marshall D,Alaev O,Bryan A,Gelfman A,Wang Z

doi

10.1111/jcpt.12774

subject

Has Abstract

pub_date

2019-02-01 00:00:00

pages

122-124

issue

1

eissn

0269-4727

issn

1365-2710

journal_volume

44

pub_type

  • Theophylline plasma clearance in critically ill geriatric patients receiving total parenteral nutrition and in control patients.

    abstract::Mean values and standard deviations are reported for theophylline plasma clearance in 45 hospitalized geriatric patients (age greater than 65 years), distributed into two groups: Group I (n = 24) included critically ill patients admitted to the ICU on total parenteral nutrition (TPN). Group II (n = 21) included patien...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2710.1990.tb00385.x

    authors: Sangrador G,Sánchez-Alcaraz A,Ubeda R,Ibañez P

    更新日期:1990-08-01 00:00:00

  • Extremely low dose of 6-mercaptopurine in a Chinese child with acute lymphoblastic leukaemia and multiple pharmacogenetic mutations.

    abstract:WHAT IS KNOWN AND OBJECTIVES:Thiopurines are cornerstone drugs in the treatment of acute lymphoblastic leukaemia (ALL), but their use can be complicated by the incidence of life-threatening leucopenia. CASE DESCRIPTION:We describe a case of a 6-year-old Chinese boy with B-ALL receiving extremely low dose of 6-mercapto...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type:

    doi:10.1111/jcpt.13255

    authors: Zhai XY,Zhou Y,Dong L,Nie AQ,Zhi LJ,Jacqz-Aigrain E,Wang TY,Wang L,Zhao W

    更新日期:2021-02-01 00:00:00

  • Comparison of sedation with dexmedetomidine vs propofol during hysteroscopic surgery: Single-centre randomized controlled trial.

    abstract:WHAT IS KNOWN AND OBJECTIVE:The most appropriate sedative agent for conscious sedation in minor hysteroscopic surgeries is still unclear. Dexmedetomidine a sedative and analgesic agent, may be appropriate for outpatient procedures. The aim of our study was to compare the sedative, analgesic and hemodynamic effects of d...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/jcpt.12793

    authors: Bingol Tanriverdi T,Koceroglu I,Devrim S,Gura Celik M

    更新日期:2019-04-01 00:00:00

  • Baking soda misuse as a home remedy: case experience of the California Poison Control System.

    abstract:WHAT IS KNOWN AND OBJECTIVE:Baking soda is a common household product promoted by the manufacturer as an antacid. It contains sodium bicarbonate and has the potential for significant toxicity when ingested in excessive amounts. Characterizing the patterns and outcomes from the misuse of baking soda as a home remedy can...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/jcpt.12113

    authors: Al-Abri SA,Kearney T

    更新日期:2014-02-01 00:00:00

  • Retrospective audit of antimicrobial prescribing practices for acute exacerbations of chronic obstructive pulmonary diseases in a large regional hospital.

    abstract:WHAT IS KNOWN AND OBJECTIVE:Chronic obstructive pulmonary disease (COPD) is associated with significant morbidity and mortality, and frequent exacerbations are associated with an increased risk of death, deterioration in lung function and reduced quality of life. Current Australian guidelines developed by the Lung Foun...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/jcpt.12514

    authors: Brownridge DJ,Zaidi STR

    更新日期:2017-06-01 00:00:00

  • Randomized trial comparing efficacies of zoledronate and alendronate for improving bone mineral density and inhibiting bone remodelling in women with post-menopausal osteoporosis.

    abstract:WHAT IS KNOWN AND OBJECTIVE:Bisphosphonates are the first-line medications for treating osteoporosis. The aim of our prospective study was to compare the efficacy of zoledronate with that of alendronate in women with post-menopausal osteoporosis based on the evaluations of bone mineral density (BMD) and serum levels of...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章,随机对照试验

    doi:10.1111/jcpt.12429

    authors: Tan W,Sun J,Zhou L,Li Y,Wu X

    更新日期:2016-10-01 00:00:00

  • Influence of age and co-medication on steady-state phenobarbital serum level-dose ratios in Japanese paediatric patients.

    abstract::The effects of age and co-medication on steady-state phenobarbital (PB) level-dose (L/D) ratios were evaluated retrospectively in 539 paediatric patients. The PB L/D ratio increased significantly with age up to 15 years. Associated anti-epileptic therapy affected the PB L/D ratio, which was significantly increased in ...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2710.1992.tb01301.x

    authors: Yukawa E,Higuchi S,Aoyama T

    更新日期:1992-08-01 00:00:00

  • Incretin-based therapy and acute cholecystitis: a review of case reports and EudraVigilance spontaneous adverse drug reaction reporting database.

    abstract:WHAT IS KNOWN AND OBJECTIVE:Glucagon-like peptide-1 (GLP-1) receptor agonists delay gastric and bowel emptying. A similar inhibitory effect of GLP-1 on gallbladder motility has been suggested, possibly leading to an increased risk of cholecystitis related to incretin-based medications, which include GLP-1 antagonists. ...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章,评审

    doi:10.1111/jcpt.12373

    authors: Pizzimenti V,Giandalia A,Cucinotta D,Russo GT,Smits M,Cutroneo PM,Trifirò G

    更新日期:2016-04-01 00:00:00

  • Fatal interstitial lung disease induced by rituximab-containing chemotherapy, treatment with TNF-α antagonist and cytokine profiling: a case-report and review of the literature.

    abstract:WHAT IS KNOWN AND OBJECTIVE:Rituximab, an anti-CD20 monoclonal antibody, is widely used with good response for the treatment of B-cell lymphoma and various refractory autoimmune diseases. Although rituximab is effective, rare but serious pulmonary adverse reactions have been reported. We report on a case of rituximab-i...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/jcpt.12052

    authors: Wu Y,Jia Y,Xu J,Shuai X,Wu Y

    更新日期:2013-06-01 00:00:00

  • A phase I trial assessing the safety, tolerability, pharmacokinetic and pharmacodynamic characteristics of single-dose Auron Misheil therapy in healthy male subjects.

    abstract:BACKGROUND AND OBJECTIVE:Auron Misheil therapy (AMT) is a combination of widely used pharmaceuticals and herbal components that has been used since the 1980s as a supportive therapy, mainly in end-stage cancer patients on a compassionate basis. This phase I study was conducted to assess the safety, tolerability, and ph...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2710.2009.01087.x

    authors: Scheele J,Diergarten K,Drevs J,Niazi FR

    更新日期:2013-02-01 00:00:00

  • The quality of essential antimicrobial and antimalarial drugs marketed in Rwanda and Tanzania: influence of tropical storage conditions on in vitro dissolution.

    abstract:OBJECTIVE:The quality of 33 formulations of essential antimicrobial and antimalarial drugs (amoxicillin capsules, metronidazole tablets, sulfamethoxazole/trimethoprim tablets, quinine tablets and sulphadoxine/pyrimethamine tablets) marketed in Rwanda and Tanzania was assessed and the influence of tropical storage condi...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2710.2004.00568.x

    authors: Kayumba PC,Risha PG,Shewiyo D,Msami A,Masuki G,Ameye D,Vergote G,Ntawukuliryayo JD,Remon JP,Vervaet C

    更新日期:2004-08-01 00:00:00

  • Effect of food on the bioavailability of a slow-release theophylline formulation.

    abstract::A study was conducted in two groups of healthy volunteers to assess whether the time of administration (10 min before the meal versus 60 min after the meal) influences the pharmacokinetics and absorption kinetics of a slow-release theophylline product (Teonova). In the first group (Group A, n = 10), the drug was given...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1365-2710.1988.tb00509.x

    authors: Boner AL,Sette L,Messori A,Plebani M,Vallone G,Martini N

    更新日期:1988-02-01 00:00:00

  • Pharmacokinetics of intravenous midazolam during epidural anaesthesia.

    abstract::Midazolam concentration curves versus time were analysed in 10 otherwise healthy patients (ASA I-II) with inferior limb pathologies. The benzodiazepine was used as an adjuvant agent to epidural anaesthesia in view of its lower residual effect compared with other intravenous benzodiazepines. Midazolam pharmacokinetics...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2710.1991.tb00306.x

    authors: Sánchez-Alcaraz A,Sangrador G,Laguarda M,Quintana B

    更新日期:1991-06-01 00:00:00

  • Acute teriflunomide overdose with relatively mild symptoms: A case report.

    abstract:WHAT IS KNOW AND OBJECTIVE:Teriflunomide is indicated for the treatment of adult patients with relapsing-remitting multiple sclerosis. CASE SUMMARY:We present a rare intoxication with a high dose (672 mg) of teriflunomide. According to its product label, the only known treatment is the administration of colestyramine ...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type:

    doi:10.1111/jcpt.13360

    authors: Mian P,van Haaften WT,Assink M,van Drie-Pierik RJHM

    更新日期:2021-01-09 00:00:00

  • Compliance measure development and assessment of theophylline therapy in ambulatory patients.

    abstract::The objectives of this study were: (a) to develop a drug serum level-based compliance measure which incorporated pharmacokinetic analysis of patient and drug parameters and to compare it to refill records, an indirect measure, and (b) to use that measure to determine whether pharmacist consultation increased complianc...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: De Tullio PL,Kirking DM,Arslanian C,Olson DE

    更新日期:1987-02-01 00:00:00

  • Evaluation of pregabalin-induced adverse events related to falls using the FDA adverse event reporting system and Japanese Adverse Drug Event Report databases.

    abstract:WHAT IS KNOWN AND OBJECTIVE:Pregabalin is used for neuropathic and postherpetic pain and generalized anxiety. The aim of this study was to obtain the onset profiles of adverse events (AE) related to falls (AEFs) such as "somnolence," "dizziness," "loss of consciousness" and "fall" onset and several clinical factor comb...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/jcpt.12790

    authors: Mukai R,Hasegawa S,Umetsu R,Nakao S,Shimada K,Uranishi H,Masuta M,Suzuki H,Nishibata Y,Nakamura M

    更新日期:2019-04-01 00:00:00

  • Factors limiting adherence to antiepileptic treatment: A French online patient survey.

    abstract:WHAT IS KNOWN AND OBJECTIVE:There are various reasons why antiepileptic treatment can fail. One is drug-resistant epilepsies, but non-adherence, or poor adherence, to treatment may make some patients' treatment ineffective. The consequences of poor adherence include treatment failure or introduction of more complex tre...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/jcpt.12615

    authors: Laville F,Montana M,Roux N,Rathelot P,Giorgi R,Vanelle P

    更新日期:2018-02-01 00:00:00

  • Heparin-induced acute adverse reaction--case report of a patient with acute trauma and a genetic predisposition to thrombotic events: a concurrence of events.

    abstract:WHAT IS KNOWN AND OBJECTIVE:The most common complication of heparin therapy is bleeding. Allergic reactions to heparin are rare, and the mechanisms are poorly understood. We report on a case of acute systemic reaction after subcutaneous injections of a low-molecular-weight heparin (LMWH) in a patient with a genetic pre...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章,评审

    doi:10.1111/j.1365-2710.2012.01360.x

    authors: Leone S,Zuccoli ML,Fucile C,Storace S,Martelli A,Mattioli F

    更新日期:2012-12-01 00:00:00

  • Treatment of acute otitis media in patients with a reported penicillin allergy.

    abstract::Otitis media occurs commonly in children, and is usually treated with an antibiotic. In this case report, amoxicillin was prescribed for a 6-year-old boy suffering from acute otitis media. As he had previously experienced a rash after the administration of a penicillin, the medication order was switched from amoxicill...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1046/j.1365-2710.2000.00268.x

    authors: Falconer CL,Gardner DM

    更新日期:2000-06-01 00:00:00

  • Investigation of urinary levels of salbutamol in asthmatic patients receiving inhaled therapy.

    abstract:AIM:Some studies have indicated that over-reliance on inhaled bronchodilator (beta 2-agonist) therapy may worsen asthma control and increase morbidity. The aim of this study was to measure urinary concentrations of salbutamol, the most commonly used bronchodilator, in a relatively large sample of asthmatic patients and...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2710.1997.tb00005.x

    authors: Jacobson GA,Peterson GM,McLean S

    更新日期:1997-04-01 00:00:00

  • Population analysis for the optimization of digoxin treatment in Japanese paediatric patients.

    abstract:BACKGROUND AND OBJECTIVES:Information about the pharmacokinetics of digoxin in paediatric patients is limited. We therefore aimed to investigate the effects of physiological factors on the digoxin clearance in Japanese paediatric patients. METHOD:We used routinely collected therapeutic drug monitoring data (n=544), de...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1046/j.1365-2710.1999.00221.x

    authors: Suematsu F,Minemoto M,Yukawa E,Higuchi S

    更新日期:1999-06-01 00:00:00

  • Gemtuzumab ozogamicin-induced sinusoidal obstructive syndrome treated with defibrotide: a case report.

    abstract::New treatments for relapse of acute myeloid leukaemia (AML), include gemtuzumab ozogamicin (GO), an anti-CD33 monoclonal antibody. We describe a second case of GO-induced sinusoidal obstructive syndrome (SOS) effectively treated with defibrotide (DF). No stem-cell transplantation was involved. On day 23 after the firs...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2710.2006.00742.x

    authors: Lannoy D,Decaudin B,Grozieux de Laguérenne A,Barrier F,Pignon JM,Wetterwald M,Odou P

    更新日期:2006-08-01 00:00:00

  • Population pharmacokinetic study of gentamicin and a Bayesian approach in patients with renal impairment.

    abstract::A population pharmacokinetic study was conducted on a total of 70 patients receiving gentamicin therapy. The patients included those with normal renal function and those with varying degrees of renal impairment. The parameters studied were the apparent volume of distribution and the plasma clearance of gentamicin. The...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2710.1989.tb00240.x

    authors: Lanao JM,Berrocal A,Calvo MV,Perez M,de la Calle B,Domínguez-Gil A

    更新日期:1989-06-01 00:00:00

  • An evaluation of the potential interaction between enalapril and amiloride.

    abstract::Enalapril was shown to have no effect on the serum potassium of patients (n = 16) already taking Frusemide and Amiloride. Furthermore, there was no difference in serum potassium levels of the group taking a combination of Enalapril, Frusemide and Amiloride when compared to a similar group of patients taking Frusemide ...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2710.1987.tb00543.x

    authors: Radley AS,Fitzpatrick RW

    更新日期:1987-10-01 00:00:00

  • Genetic predisposition to atorvastatin-induced myopathy: a case report.

    abstract:WHAT IS KNOWN AND OBJECTIVE:The major clinical complication of statins is a variety of muscle complaints ranging from myalgia to rhabdomyolysis. There is growing evidence that carriers of genetic polymorphisms in the enzymes and transporters implicated in statin disposition, particularly the SLCO1B1 gene, are at increa...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2710.2012.01337.x

    authors: Francesca Notarangelo M,Marziliano N,Antonietta Demola M,Pigazzani F,Guidorossi A,Angelica Merlini P,Ardissino D

    更新日期:2012-10-01 00:00:00

  • LncRNA TUG1 overexpression promotes apoptosis of cardiomyocytes and predicts poor prognosis of myocardial infarction.

    abstract:WHAT IS KNOWN AND OBJECTIVE:Long non-coding RNAs (lncRNAs) have been proved to regulate. LncRNA TUG1 is well characterized in cancer biology. This study was carried out to investigate the molecular function of lncRNA TUG1 in myocardial infarction. METHODS:This study enrolled 58 MI patients and 52 healthy volunteers, a...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/jcpt.13190

    authors: Li B,Wu Y

    更新日期:2020-12-01 00:00:00

  • Diagnosis and treatment of low T3 syndrome in neurocritical patients.

    abstract:WHAT IS KNOWN AND OBJECTIVE:Low levels of serum triiodothyronine (T3) are a strong predictor of mortality and poor prognosis in critical care patients. Few reports, however, have focused on neurocritical patients. The application of hormone replacement therapy (HRT) in the treatment of neurocritical patients with low T...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/jcpt.13162

    authors: Chen Y,Chang J,Yin R,Wen J,Ma B,Zuo W,Zhang X,Wei J

    更新日期:2020-08-01 00:00:00

  • Management of acute coronary syndrome in a tertiary care general medical unit in Sri Lanka: how closely do we follow the guidelines?

    abstract:BACKGROUND AND OBJECTIVES:Acute coronary syndrome (ACS) is a leading cause of death. Correct implementation of evidence-based guidelines should improve outcome. We conducted this study to determine to what extent management of ACS in a tertiary care medical ward in Sri Lanka adhered to current guidelines. STUDY METHOD...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/j.1365-2710.2009.01115.x

    authors: Rajapakse S,Rodrigo PC,Selvachandran J

    更新日期:2010-08-01 00:00:00

  • Application of dynamic laser scattering to the quality control of injectable drugs: polymer formation in ampicillin solution.

    abstract:OBJECTIVE:To assess the usefulness of dynamic laser scattering for monitoring the stability of ampicillin after reconstitution from commercially available vials with respect to the polymer formation and potency. METHODS:Polymer formation and the remaining potency of the reconstituted ampicillin solution were estimated...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1046/j.1365-2710.2002.00397.x

    authors: Sendo T,Teshima D,Makino K,Mishima K,Itoh Y,Oishi R

    更新日期:2002-04-01 00:00:00

  • Evaluation of the trends and appropriateness of fluoroquinolone use in the outpatient treatment of acute uncomplicated cystitis at five family practice clinics.

    abstract:WHAT IS KNOWN AND OBJECTIVE:Despite recommendations to avoid fluoroquinolones (FQs) as a first-line treatment for uncomplicated cystitis, recent data suggest that FQs remain widely prescribed. Therefore, the objectives of this study were to evaluate the appropriateness of empiric FQ use compared to nitrofurantoin for u...

    journal_title:Journal of clinical pharmacy and therapeutics

    pub_type: 杂志文章

    doi:10.1111/jcpt.13099

    authors: Robinson TF,Barsoumian AE,Aden JK,Giancola SE

    更新日期:2020-06-01 00:00:00