Ovarian preservation during the surgical treatment of early stage endometrial cancer: a nation-wide study conducted by the Korean Gynecologic Oncology Group.

abstract：OBJECTIVE:The aims of this study were (1) to examine whether HPV DNA is persistently detected in the cervix after therapeutic conization for CIN 3 and (2) to explore whether a patient with persistence of HPV infection is at risk of developing recurrent disease. METHODS:Of 74 patients referred with CIN 3, 58 who were t...

journal_title：Gynecologic oncology

authors： Nagai Y,Maehama T,Asato T,Kanazawa K

更新日期：2000-11-01 00:00:00

abstract：OBJECTIVES:To determine the incidence and prognostic implications of positive mesorectal lymph nodes in patients undergoing total pelvic exenteration for recurrent gynecologic malignancies. METHODS:We performed a retrospective chart review of all patients who had undergone total pelvic exenteration for a gynecologic m...

journal_title：Gynecologic oncology

authors： Mourton SM,Chi DS,Sonoda Y,Alektiar KM,Venkatraman ES,Barakat RR,Abu-Rustum NR

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Primary cancer of the vulva is not common, constituting only 3-5% of all gynecologic malignancies and <1% of all cancer in the female. Metastatic tumors of the vulva are even more unusual, constituting only 5-8% of all vulvar cancers. CASE:A 32-year-old female underwent total mastectomy with axillary lymph ...

journal_title：Gynecologic oncology

authors： Sheen-Chen SM,Eng HL,Huang CC

更新日期：2004-09-01 00:00:00

abstract：:The objective of this phase II multicenter study was to assess the efficacy and tolerance of triptorelin (a sustained-release LHRH agonist) in advanced or recurrent endometrial cancer. A total of 101 monthly intramuscular injections were administered to 24 eligible patients (median number/patient = 3; range 1-12). Mai...

journal_title：Gynecologic oncology

authors： Lhommé C,Vennin P,Callet N,Lesimple T,Achard JL,Chauvergne J,Luporsi E,Chinet-Charrot P,Coudert B,Couette JE,Guastalla JP,Lebrun D,Ispas S,Blumberg J

更新日期：1999-11-01 00:00:00

abstract：OBJECTIVES:The goal of this case review was to evaluate the influence of complete surgical versus clinical staging, including the impact of ovarian preservation, on the outcome of young patients with endometrial carcinoma. METHODS:A retrospective chart review was performed on all patients with endometrial cancer diagn...

journal_title：Gynecologic oncology

authors： Richter CE,Qian B,Martel M,Yu H,Azodi M,Rutherford TJ,Schwartz PE

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVE:The objective was to determine the frequency with which regression or progression of disease without treatment occurred in women diagnosed with squamous cell cervical carcinoma in situ (CIS) during pregnancy. METHODS:. A retrospective chart review of all women evaluated at the University of Iowa Colposcopy C...

journal_title：Gynecologic oncology

authors： Coppola A,Sorosky J,Casper R,Anderson B,Buller RE

更新日期：1997-11-01 00:00:00

abstract：OBJECTIVE:This study was undertaken to evaluate the efficacy of postoperative concurrent chemoradiotherapy (CCRT) and to investigate the recurrence and survival rates after adjuvant CCRT in high-risk early cervical cancer (stages IA2, IB, IIA) patients who were treated by radical hysterectomy and pelvic lymphadenectomy...

journal_title：Gynecologic oncology

authors： Ryu HS,Chun M,Chang KH,Chang HJ,Lee JP

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVE:To investigate whether alteration of BRCA1 tumor suppressor gene occurs in sporadic endometrial carcinomas. METHODS:Genomic DNAs were prepared from 33 consecutively collected endometrial carcinoma tissues for BRCA1 mutational analysis. To screen for BRCA1 mutation, polymerase chain reaction (PCR) amplificati...

journal_title：Gynecologic oncology

authors： Liu FS,Ho ES,Shih RT,Shih A

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:Nicaragua has some of the highest rates of cervical cancer in Latin America and the world. In 2003, the Nicaraguan Ministry of Health, the Central American Institute of Health and the Maria Luisa Ortiz Clinic combined efforts to create an effective remote rural service network, with centralized quality-contr...

journal_title：Gynecologic oncology

authors： Howe SL,Vargas DE,Granada D,Smith JK

更新日期：2005-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to determine the cost-effectiveness of selective lymphadenectomy using a preoperative prediction model compared to routine lymphadenectomy for patients undergoing surgery for endometrial cancer in the US and Korea. METHODS:We used a modified Markov model to estimate clinical and eco...

journal_title：Gynecologic oncology

authors： Lee JY,Cohn DE,Kim Y,Lee TJ,Barnett JC,Kim JW,Jeon YW,Kim K,Park SM,Kang S

更新日期：2014-12-01 00:00:00

abstract：:Only one case of endometrial transitional cell carcinoma (TCC) has been previously reported in the literature. We report a second case. In both the previously reported case and in this case there was a separate focus of TCC in the adnexa. Both patients were treated with adjuvant whole pelvic radiation and are alive an...

journal_title：Gynecologic oncology

authors： Spiegel GW,Austin RM,Gelven PL

更新日期：1996-02-01 00:00:00

abstract：OBJECTIVE:The goal of this study was to determine if three-dimensional power Doppler ultrasound improves the specificity for ovarian cancer detection as compared with two-dimensional ultrasound. METHODS:Seventy-one women with a known complex pelvic mass were referred for a preoperative ultrasound evaluation with both ...

journal_title：Gynecologic oncology

authors： Cohen LS,Escobar PF,Scharm C,Glimco B,Fishman DA

更新日期：2001-07-01 00:00:00

abstract：:The usefulness of fine needle sampling (FNS) under transvaginal ultrasound guidance in gynecologic oncology patients is evaluated in this study. Between 1990 and 1993, 101 FNS under transvaginal ultrasound guidance were performed in 88 sessions. All targets were located deep in the pelvis and their median diameter was...

journal_title：Gynecologic oncology

authors： Zanetta G,Brenna A,Pittelli M,Lissoni A,Trio D,Riotta S

更新日期：1994-07-01 00:00:00

abstract：OBJECTIVE:Doxorubicin has reported activity in advanced and recurrent cervical cancer but hematologic toxicity has limited its use in some combinations. To determine the level of activity and potential for use in future combinations, a phase II trial of pegylated liposomal doxorubicin as second-line therapy in advanced...

journal_title：Gynecologic oncology

authors： Rose PG,Blessing JA,Lele S,Abulafia O

更新日期：2006-08-01 00:00:00

abstract：:Ovarian germ cell tumors (GCTs) are rare in adults, but are more common in adolescents and young adults. Contemporary management of ovarian GCTs is evolving as collaboration among pediatric, medical, and gynecologic oncologists increases, and studies increasingly incorporate female adult patients. Despite an improved ...

journal_title：Gynecologic oncology

authors： Veneris JT,Mahajan P,Frazier AL

更新日期：2020-08-01 00:00:00

abstract：PURPOSE:A phase II trial was conducted to evaluate the anti-tumor activity and adverse effects of capecitabine in women with measurable platinum-sensitive ovarian cancer or platinum-sensitive primary peritoneal cancer and to explore the ability of thymidylate synthase (TS), dihydropyrimidine dehydrogenase (DPD), and th...

journal_title：Gynecologic oncology

authors： Garcia AA,Blessing JA,Lenz HJ,Darcy KM,Mannel RS,Miller DS,Husseinzadeh N,Gynecologic Oncology Group.

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:Many studies have examined the relationship between worry and cancer screening. Due to methodological inconsistencies, results of these studies have varied and few conclusions can be made when generalizing across studies. The purpose of the current study was to better understand the worry-cancer screening rel...

journal_title：Gynecologic oncology

authors： Ruberg JL,Helm CW,Felleman BI,Helm JE,Studts JL

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVE:To quantify the impact of preoperative hypoalbuminemia on 30-day mortality and morbidity after gynecologic cancer surgery. METHODS:Patients included in the National Surgical Quality Improvement Program (NSQIP) dataset who underwent any non-emergent surgery for gynecologic malignancy between 1/1/2008 and 12/3...

journal_title：Gynecologic oncology

authors： Uppal S,Al-Niaimi A,Rice LW,Rose SL,Kushner DM,Spencer RJ,Hartenbach E

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:This two-stage Phase II study assessed the activity of single agent alisertib in patients with recurrent/persistent uterine leiomyosarcoma (uLMS). METHODS:Eligibility criteria included histologically-confirmed, recurrent or persistent uLMS, age≥18, 1-2 prior cytotoxic regimens, and RECIST version 1.1 measura...

journal_title：Gynecologic oncology

authors： Hyman DM,Sill MW,Lankes HA,Piekarz R,Shahin MS,Ridgway MR,Backes F,Tenney ME,Mathews CA,Hoffman JS,Aghajanian C,Hensley ML

更新日期：2017-01-01 00:00:00

abstract：OBJECTIVES:Recent literature has highlighted histological types of ovarian carcinoma as distinct diseases, each with unique clinical and molecular features. Historically, the diagnosis of ovarian clear cell carcinoma (CCC) has been of concern to both patients and physicians due to reports that CCC is associated with a ...

journal_title：Gynecologic oncology

authors： Anglesio MS,Carey MS,Köbel M,Mackay H,Huntsman DG,Vancouver Ovarian Clear Cell Symposium Speakers.

更新日期：2011-05-01 00:00:00

abstract：OBJECTIVE:UPSC is similar to papillary serous ovarian carcinoma in its histology and pattern of spread. The survival advantage with optimal debulking for ovarian cancer has been demonstrated. We examined our experience with UPSC. METHODS:Seventy-eight UPSC patients were seen between 1995 and 2008 at Rush University Me...

journal_title：Gynecologic oncology

authors： Patsavas K,Woessner J,Gielda B,Rotmensch J,Yordan E,Bitterman P,Guirguis A

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVE:Chimeric antigen receptor (CAR)-T cell strategies ideally target a surface antigen that is exclusively and uniformly expressed by tumors; however, no such antigen is known for high-grade serous ovarian carcinoma (HGSC). A potential solution involves combinatorial antigen targeting with AND or OR logic-gating....

journal_title：Gynecologic oncology

authors： Banville AC,Wouters MCA,Oberg AL,Goergen KM,Maurer MJ,Milne K,Ashkani J,Field E,Ghesquiere C,Jones SJM,Block MS,Nelson BH

更新日期：2021-02-01 00:00:00

abstract：:The analysis of the lytic mechanism initiated by TNFalpha in three human ovarian cell lines (CAOV-3, SK-OV-3, and OVCAR-3) and in three human cervical cell lines (SIHa, HT-3, and ME-180) in the presence of inhibitors of protein synthesis indicates that this lytic mechanism is similar to the protein synthesis-independe...

journal_title：Gynecologic oncology

authors： Powell CB,Scott JH,Collins JL

更新日期：1996-07-01 00:00:00

abstract：OBJECTIVE:A multicenter phase II trial was conducted to assess the efficacy and toxicity of concurrent chemoradiotherapy (CCRT) with high-dose-rate intracavitary brachytherapy (HDR-ICBT) using a low cumulative prescribed dose schedule in patients with locally advanced uterine cervical cancer. METHODS:The Japanese Gyne...

journal_title：Gynecologic oncology

authors： Toita T,Kitagawa R,Hamano T,Umayahara K,Hirashima Y,Aoki Y,Oguchi M,Mikami M,Takizawa K,Cervical Cancer (Vulva Cancer) Committee of Japanese Gynecologic Oncology Group (JGOG).

更新日期：2012-08-01 00:00:00

abstract：OBJECTIVE:Cyclin-dependent kinase 7 (CDK7) engages tumor growth by acting as a direct link between the regulation of transcription and the cell cycle. Here, we investigated the clinical significance of CDK7 expression and its potential as a therapeutic target in epithelial ovarian cancer (EOC). METHODS:CDK7 expression...

journal_title：Gynecologic oncology

authors： Kim J,Cho YJ,Ryu JY,Hwang I,Han HD,Ahn HJ,Kim WY,Cho H,Chung JY,Hewitt SM,Kim JH,Kim BG,Bae DS,Choi CH,Lee JW

更新日期：2020-01-01 00:00:00

abstract：:Angiomyofibroblastoma is a rare, myxoid tumor of the vulva. To date only 12 cases have been reported in the world literature. Patients are usually premenopausal and present with a vulval mass initially diagnosed as a Bartholin's cyst. The lesions are well circumscribed and range from 0.5 to 12 cm in size. Microscopica...

journal_title：Gynecologic oncology

authors： Van der Griend MD,Burda P,Ferrier AJ

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:A case of primary neuroblastoma arising from the broad ligament with excellent response to neoadjuvant bleomycin, etoposide, and cisplatin (BEP) is reported. CASE:A 48-year-old woman, G0, who presented with acute renal failure, an enlarged pelvic mass, and abdominal pain was diagnosed with adult neuroblasto...

journal_title：Gynecologic oncology

authors： Milam MR,Gabel SF,Milam RA,Liu J,Ramirez PT

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:The aim of this study is to investigate whether the presence of endometriosis is a prognostic factor in patients diagnosed with clear cell carcinoma (CCC) of the ovary. METHODS:Retrospective chart review was performed to all patients diagnosed with CCC and endometriosis between 1975 and 2002. All pathology r...

journal_title：Gynecologic oncology

authors： Orezzoli JP,Russell AH,Oliva E,Del Carmen MG,Eichhorn J,Fuller AF

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVE:To determine the antitumor activity and toxicity profile of gemcitabine as second-line chemotherapy in patients with recurrent or persistent uterine leiomyosarcoma (LMS). METHODS:Intravenous gemcitabine was administered over 30 min at a dose of 1000 mg/m(2) on days 1, 8, 15, with cycles repeated every 28 day...

journal_title：Gynecologic oncology

authors： Look KY,Sandler A,Blessing JA,Lucci JA 3rd,Rose PG,Gynecologic Oncology Group (GOG) Study.

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVE:Determining whether carcinomas concurrently involving endometrium and ovary are independent primary tumors (IPTs) or endometrial carcinomas with ovarian metastases (at least stage IIIA endometrial cancers, IIIA-EC) using clinicopathologic criteria is often challenging. Recent genomic studies showed that most ...

journal_title：Gynecologic oncology

authors： Turashvili G,Gómez-Hidalgo NR,Flynn J,Gonen M,Leitao MM Jr,Soslow RA,Murali R

更新日期：2019-01-01 00:00:00