The molecular and genetic mechanisms of neocortex development.

abstract：:Staphylococci are common pathogens in the neonatal period. Increased survival of premature infants leads to prolonged hospital stay with associated risk factors for developing invasive staphylococcal disease. Challenges of diagnosing coagulase-negative staphylococcal infections result in conflicting definitions and in...

journal_title：Clinics in perinatology

authors： Blanchard AC,Quach C,Autmizguine J

更新日期：2015-03-01 00:00:00

abstract：:Birth injuries of the brachial plexus are fairly common, but the majority of affected newborns make quick recoveries without any specific intervention. A minority suffer more severe injuries that lead to varying degrees of life-long disability. Happily, modern microsurgical techniques permit reconstruction of certain ...

journal_title：Clinics in perinatology

authors： Piatt JH Jr

更新日期：2005-03-01 00:00:00

abstract：:The care of extremely premature infants involves a number of complex clinical and ethical issues. The ethical and scientific quality of decisions made in the care of these infants has profound long-term consequences for these infants and their families. In circumstances when it is unclear whether intensive care should...

journal_title：Clinics in perinatology

authors： Tyson JE,Stoll BJ

更新日期：2003-06-01 00:00:00

abstract：:Prevention of harm from medication errors has become a national priority. Medication errors in the neonatal intensive care unit are common, and most can be avoided. This article reviews the prevalence and types of medication errors affecting the care of the neonate and summarizes approaches that have been used to redu...

journal_title：Clinics in perinatology

authors： Stavroudis TA,Miller MR,Lehmann CU

更新日期：2008-03-01 00:00:00

abstract：:Oxygen therapy is an essential part of neonatal care. Targeting oxygen saturations and preventing hypoxemia and hyperoxemia is difficult, particularly in preterm infants. The mode of oxygen delivery directly affects the stability of oxygen saturations, hypoxemia, and hyperoxemia. This stability has important clinical ...

journal_title：Clinics in perinatology

authors： Travers CP,Carlo WA

更新日期：2019-09-01 00:00:00

abstract：:Most pharmacokinetic and biologic attributes of digitalis are age dependent. They are determined in great measure by the chemical structure of the specific cardiac glycoside being used. These effects differ in the intact normal circulation and in heart failure because of the altered autonomic nervous system and hormon...

journal_title：Clinics in perinatology

authors： Hastreiter AR,John EG,van der Horst RL

更新日期：1988-09-01 00:00:00

abstract：:Decision-making for extremely immature preterm infants at the margins of viability is ethically, professionally, and emotionally complicated. A standard for prenatal consultation should be developed incorporating assessment of parental decision-making preferences and styles, a communication process involving a recipro...

journal_title：Clinics in perinatology

authors： Haward MF,Kirshenbaum NW,Campbell DE

更新日期：2011-09-01 00:00:00

abstract：:The phenomenal developments in molecular genetics and technological refinements which have occurred over the past decade are revolutionizing the area of prenatal genetics. State-of-the-art care commences with comprehensive preconceptional counseling. Prenatal diagnosis is now feasible from the moment of conception onw...

journal_title：Clinics in perinatology

authors： Plouffe L Jr,Donahue J

更新日期：1994-12-01 00:00:00

abstract：:In patients with chronic renal disease, all advice and decisions must take into account the balance between pregnancy outcome and the long-term impact that pregnancy might have on the disease. To help the clinician address these concerns, the authors focus on the renal changes in normal pregnancy, the problems of chro...

journal_title：Clinics in perinatology

authors： Davison JM,Katz AI,Lindheimer MD

更新日期：1985-10-01 00:00:00

abstract：:Insulin resistance appears to be a causative mechanism for the development of essential hypertension. Insulin resistance syndrome consists of a cluster of abnormalities that aggravate preexisting tendencies to develop hypertension, resulting in a cascade of physiologic alterations and ultimately leading to increased r...

journal_title：Clinics in perinatology

authors： Berkowitz KM

更新日期：1998-12-01 00:00:00

abstract：:Congenital cytomegalovirus is the most common viral congenital infection, and affects up to 2% of neonates. Significant sequelae may develop after congenital cytomegalovirus, including hearing loss, cognitive defects, seizures, and death. Zika virus is an emerging virus with perinatal implications; a congenital Zika v...

journal_title：Clinics in perinatology

authors： Wood AM,Hughes BL

更新日期：2018-06-01 00:00:00

abstract：:Human milk provided by healthy and well-nourished mothers is believed to cover the infant's nutrient requirements during the first half year of life. It is composed of a mixture of nutritive components as well as other bioactive factors with relevant physiologic effects in the neonate infant. Human milk composition ha...

journal_title：Clinics in perinatology

authors： Kunz C,Rodriguez-Palmero M,Koletzko B,Jensen R

更新日期：1999-06-01 00:00:00

abstract：:Beta-sympathomimetic agents are used extensively in obstetrics to inhibit premature labor. Knowledge of the pharmacology, mode of action on smooth muscle, and cardiovascular and metabolic side effects of these agents is essential for the obstetrician and perinatologist. This review article draws extensively on recent ...

journal_title：Clinics in perinatology

authors： Nuwayhid B,Rajabi M

更新日期：1987-12-01 00:00:00

abstract：:The educational programs that have been developed in newborn special care facilities have two purposes: first, they teach personnel the manual skills that are necessary to manage the sick newborn infant; second, they provide personnel with a better understanding of neonatal pathophysiology so that they can begin to re...

journal_title：Clinics in perinatology

authors： Coen RW

更新日期：1976-09-01 00:00:00

abstract：:Rhinitis is extremely common during pregnancy, and asthma is one of the most common potentially serious medical problems to complicate pregnancy. Cutaneous allergy (urticaria/angioedema and eczema) also may occur during pregnancy. All of these entities may worsen with pregnancy in some patients and appear to improve i...

journal_title：Clinics in perinatology

authors： Schatz M,Zeiger RS

更新日期：1997-06-01 00:00:00

abstract：:As a standard of care for preterm/term newborns effective pain management may improve their clinical and neurodevelopmental outcomes. Neonatal pain is assessed using context-specific, validated, and objective pain methods, despite the limitations of currently available tools. Therapeutic approaches reducing invasive p...

journal_title：Clinics in perinatology

authors： Hall RW,Anand KJ

更新日期：2014-12-01 00:00:00

abstract：:Preterm birth is a major complication of pregnancy and remains a leading cause of neonatal morbidity and mortality worldwide. Improvements in the authors' understanding of the pathophysiology of preterm labor have led to the development of novel diagnostic tools of use to identify women at greatest risk for preterm bi...

journal_title：Clinics in perinatology

authors： Ramsey PS,Andrews WW

更新日期：2003-12-01 00:00:00

abstract：:We have learned from prenatal diagnosis that there is a wide spectrum of clinical severity for fetuses that have a lung mass. Accurate prognostic information is necessary for providing appropriate management and parental counseling. If an associated life-threatening anomaly is present or if the mother is ill with the ...

journal_title：Clinics in perinatology

authors： Adzick NS

更新日期：2003-09-01 00:00:00

abstract：:The primary aim of this article is to define good lighting for caregivers(both medical staff and families) working in the hospital neonatal intensive care unit (NICU) and other areas associated with the critical care environment. Defining good lighting requires understanding that lighting is not only important for the...

journal_title：Clinics in perinatology

authors： Rea M

更新日期：2004-06-01 00:00:00

abstract：:Most allegations in obstetric lawsuits against obstetrician-gynecologists relate in some manner to the management of labor and delivery; few solely involve perceived flaws in prenatal or postpartum care. Although many of these cases accuse the defendant of not having properly monitored the fetus during labor for signs...

journal_title：Clinics in perinatology

authors： Cohen WR,Schifrin BS

更新日期：2007-06-01 00:00:00

abstract：:The role of infection in the pathogenesis of preterm labor and delivery, and the specific mechanisms through which this association is demonstrated are presented. Cellular and biochemical changes that initiate parturition in the setting of infection are discussed, particularly prostaglandins and cytokines. ...

journal_title：Clinics in perinatology

authors： Gomez R,Ghezzi F,Romero R,Muñoz H,Tolosa JE,Rojas I

更新日期：1995-06-01 00:00:00

abstract：:Extracorporeal membrane oxygenation (ECMO) has gained notoriety recently as a treatment of last resort for neonates at term or near term who suffer from pulmonary failure. Because of serious inherent risks, the procedure is at present reserved for infants with reversible pulmonary disease who have failed conventional ...

journal_title：Clinics in perinatology

authors： Stork E

更新日期：1988-12-01 00:00:00

abstract：:Congenital diaphragmatic hernia (CDH) is a common birth anomaly. Absence or presence of liver herniation and determination of lung-to-head ratio are the most accurate predictors of prognosis for fetuses with CDH. Though open fetal CDH repair has been abandoned, fetal endoscopic balloon tracheal occlusion promotes lung...

journal_title：Clinics in perinatology

authors： Shue EH,Miniati D,Lee H

更新日期：2012-06-01 00:00:00

abstract：:In understanding the various electrolyte disorders associated with respiratory failure, one has to appreciate how the otherwise healthy premature infant maintains extracellular fluid homeostasis. The same physiologic processes that regulate body fluids are affected to varying degrees in the infant with respiratory fai...

journal_title：Clinics in perinatology

authors： Brem AS

更新日期：1992-03-01 00:00:00

abstract：:Periviable birth carries a high risk of fetal and newborn death, and the potential for life-long complications in survivors. The family at risk for periviable birth should receive objective, accurate, and up to date information regarding fetal, newborn, and maternal risks and outcomes with delivery or with continued p...

journal_title：Clinics in perinatology

authors： Mercer BM

更新日期：2017-06-01 00:00:00

abstract：:Cesarean deliveries can be associated with moderate to severe postoperative pain. Appropriate management of pain is important because it results in better patient satisfaction, earlier mobilization, and improved maternal-infant bonding. There are many individual options for treatment of pain; however, multimodal analg...

journal_title：Clinics in perinatology

authors： Lavoie A,Toledo P

更新日期：2013-09-01 00:00:00

abstract：:Nonstress testing appears to be an effective means of identifying fetal condition. Its most definitive benefit is the identification of the "normal" fetus, which often permits a path of nonintervention. A significant benefit of the nonstress test approach is its simplicity and portability which, in a practical sense, ...

journal_title：Clinics in perinatology

authors： Paul RH

更新日期：1982-06-01 00:00:00

abstract：:The development of the flow-directed pulmonary artery catheter in the early 1970s moved invasive monitoring from the laboratory to the patient's bedside. Its current use in obstetrics is directed toward definition of certain pathophysiologic states unique to pregnancy and toward diagnosis and management of critically ...

journal_title：Clinics in perinatology

authors： Hankins GD

更新日期：1986-12-01 00:00:00

abstract：:It is clear that prostaglandins and related compounds are important in the physiology and pathophysiology of the perinatal pulmonary circulation. This article focuses on what is known about prostaglandin-related compounds (PRC) in the pulmonary circulation of the developing and newly born mammal. Also included is a di...

journal_title：Clinics in perinatology

authors： Philips JB 3rd,Lyrene RK

更新日期：1984-10-01 00:00:00

abstract：:The evaluation of the craniofacial region is a multistep process. First, sonographic skill and expertise are required to ascertain these often subtle abnormalities. Next, precise measurements must be obtained in appropriate and reproducible planes. Finally, a thorough search for other related fetal anomalies is essent...

journal_title：Clinics in perinatology

authors： Dar P,Gross SJ

更新日期：2000-12-01 00:00:00