Withdrawn: Case detection, diagnosis, and treatment of patients with primary aldosteronism: an Endocrine Society clinical practice guideline.

abstract：OBJECTIVE:C-peptide, a cleavage product of insulin, exerts biological effects in patients with type 1 diabetes mellitus, but its role in type 2 diabetes mellitus is controversial. Our aim was to examine the associations between fasting C-peptide levels and all-cause mortality, specific-cause mortality and the incidence...

journal_title：European journal of endocrinology

authors： Bo S,Gentile L,Castiglione A,Prandi V,Canil S,Ghigo E,Ciccone G

更新日期：2012-08-01 00:00:00

abstract：:Stem cell terminology has entered the lexicon of medical practitioners even though the application of harvesting stem cells to treat diseases other than haematological disorders is not yet a reality in clinical practice. All branches of medicine will be affected by the new technology, more so those related to regenera...

journal_title：European journal of endocrinology

authors： Hughes IA

更新日期：2004-11-01 00:00:00

abstract：:Glucocorticoids (GC) such as cortisol regulate multiple physiological functions, notably those involved in development, metabolism, inflammatory processes and stress, and exert their effects upon binding to the glucocorticoid receptor (GR, encoded by NR3C1 gene in humans). GC signaling follows several consecutive step...

journal_title：European journal of endocrinology

authors： Vitellius G,Lombes M

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:To examine the relationship between maternal TSH and free thyroxine (FT(4)) concentrations in early pregnancy and the risk of miscarriage, fetal or neonatal death. METHOD:Cohort study of 2497 Dutch women. TSH, FT(4), and thyroid peroxidase antibodies concentrations were determined at first booking. Child lo...

journal_title：European journal of endocrinology

authors： Benhadi N,Wiersinga WM,Reitsma JB,Vrijkotte TG,Bonsel GJ

更新日期：2009-06-01 00:00:00

abstract：CONTEXT:It is unknown whether the metabolic effects of the removal of an adrenal incidentaloma (AI) can be predicted by the assessment of cortisol hypersecretion before surgery. OBJECTIVE:To evaluate the accuracy of several criteria of hypothalamic-pituitary-adrenal axis activity in predicting the metabolic outcome af...

journal_title：European journal of endocrinology

authors： Eller-Vainicher C,Morelli V,Salcuni AS,Battista C,Torlontano M,Coletti F,Iorio L,Cairoli E,Beck-Peccoz P,Arosio M,Ambrosi B,Scillitani A,Chiodini I

更新日期：2010-12-01 00:00:00

abstract：:Several cytokines have been shown to be expressed in normal and adenomatous pituitary tissue. Recently, interleukin-8 (IL-8) mRNA was identified by reverse transcription (RT)-PCR in each of a series of 17 pituitary tumours examined. We have investigated further the presence of IL-8 mRNA, using in situ hybridisation in...

journal_title：European journal of endocrinology

authors： Suliman ME,Royds JA,Baxter L,Timperley WR,Cullen DR,Jones TH

更新日期：1999-02-01 00:00:00

abstract：:The expression of the neuropeptide Y (NPY) gene varies considerably in human pheochromocytomas, but the mechanisms for this variation have not been clarified. To investigate the regulation pattern of the NPY gene in human pheochromocytomas, we screened 16 pheochromocytomas and 9 normal adrenal tissues with Northern bl...

journal_title：European journal of endocrinology

authors： Liu J,Kahri AI,Heikkilä P,Voutilainen R

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:Sleep behavior is changing toward shorter sleep duration and a later chronotype. It results in a sleep debt that is acquitted on work-free days, inducing a small but recurrent sleep misalignment each week, referred to as "social jetlag". These sleep habits could affect health through misalignment with circad...

journal_title：European journal of endocrinology

authors： Larcher S,Gauchez AS,Lablanche S,Pépin JL,Benhamou PY,Borel AL

更新日期：2016-11-01 00:00:00

abstract：:Pituitary tumours express both somatostatin and dopamine receptors. Medical treatment with somatostatin analogues is a cornerstone of GH- and TSH-secreting tumours, while treatment with dopamine agonists is a cornerstone of prolactin-secreting tumours. Dopamine agonists have also demonstrated some efficacy in patients...

journal_title：European journal of endocrinology

authors： Colao A,Filippella M,Pivonello R,Di Somma C,Faggiano A,Lombardi G

更新日期：2007-04-01 00:00:00

abstract：:The ob protein, termed leptin, is produced by adipocytes and is thought to act as an afferent satiety signal regulating weight through suppressing appetite and stimulating energy expenditure in humans and/or rodents. Insulin has been found to be a potent stimulator of leptin expression in rodents. It is unclear at pre...

journal_title：European journal of endocrinology

authors： Kiess W,Anil M,Blum WF,Englaro P,Juul A,Attanasio A,Dötsch J,Rascher W

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:The aim was to evaluate changes of bone mineral density (BMD) and markers of bone turnover in healthy adolescents, and in adolescent users of combined oral contraceptives (COCs) with different ethinylestradiol (EE) contents. METHODS:In this prospective crossover study, 56 healthy females (15-19.5 years) wit...

journal_title：European journal of endocrinology

authors： Cibula D,Skrenkova J,Hill M,Stepan JJ

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Familial neurohypophyseal (central) diabetes insipidus (DI) is caused by mutations in the arginine vasopressin-neurophysin II (AVP-NPII) gene. The majority of cases is inherited in an autosomal dominant way. In this study, we present the clinical features of a mother and her son with autosomal dominant neuro...

journal_title：European journal of endocrinology

authors： de Fost M,van Trotsenburg AS,van Santen HM,Endert E,van den Elzen C,Kamsteeg EJ,Swaab DF,Fliers E

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:To assess the influence of craniopharyngioma or consequent surgery on melatonin secretion, and the association with fatigue, sleepiness, sleep pattern and sleep quality. DESIGN:Cross-sectional study. METHODS:A total of 15 craniopharyngioma patients were individually matched to healthy controls. In this stud...

journal_title：European journal of endocrinology

authors： Pickering L,Jennum P,Gammeltoft S,Poulsgaard L,Feldt-Rasmussen U,Klose M

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:To compare clinical and humoral parameters before and after surgery in patients with incidental adrenocortical adenomas. DESIGN:Six patients with subclinical Cushing's syndrome and nine with non-functioning adenomas were investigated before and 12 Months after removal of the mass. METHODS:Anthropometric (bo...

journal_title：European journal of endocrinology

authors： Bernini G,Moretti A,Iacconi P,Miccoli P,Nami R,Lucani B,Salvetti A

更新日期：2003-02-01 00:00:00

abstract：Objective:Hypertension and symptoms of catecholamine excess are features of pheochromocytomas and paragangliomas (PPGLs). This prospective observational cohort study assessed whether differences in presenting features in patients tested for PPGLs might assist establishing likelihood of disease. Design and methods:Pati...

journal_title：European journal of endocrinology

authors： Geroula A,Deutschbein T,Langton K,Masjkur J,Pamporaki C,Peitzsch M,Fliedner S,Timmers HJLM,Bornstein SR,Beuschlein F,Stell A,Januszewicz A,Prejbisz A,Fassnacht M,Lenders JWM,Eisenhofer G

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:Serum sclerostin levels have been reported to be inversely associated with serum 25OHD levels, but the effect of vitamin D and calcium supplementation on serum sclerostin levels is unknown. This study was carried out to determine whether vitamin D and calcium supplementation altered serum sclerostin levels in...

journal_title：European journal of endocrinology

authors： Dawson-Hughes B,Harris SS,Ceglia L,Palermo NJ

更新日期：2014-03-13 00:00:00

abstract：:The initial management of large non-functioning pituitary adenomas is surgical debulking. In some cases, postoperative radiotherapy (RT) is administered in order to reduce the likelihood of tumour regrowth. Historically, there have been concerns surrounding a number of potentially significant complications of pituitar...

journal_title：European journal of endocrinology

authors： Boelaert K,Gittoes NJ

更新日期：2001-06-01 00:00:00

abstract：:Sex steroids are important for the growth and maintenance of both the female and the male skeleton. However, the relative contribution of androgens versus estrogens in the regulation of the male skeleton is unclear. Experiments using mice with inactivated sex steroid receptors demonstrated that both activation of the ...

journal_title：European journal of endocrinology

authors： Ohlsson C,Vandenput L

更新日期：2009-06-01 00:00:00

abstract：:Approximately 15 million babies are born preterm across the world every year, with less than 37 completed weeks of gestation. Survival rates increased during the last decades with the improvement of neonatal care. With premature birth, babies are deprived of the intense intrauterine growth phase, and postnatal growth ...

journal_title：European journal of endocrinology

authors： Boguszewski MCDS,Cardoso-Demartini AA

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:To characterise distinctive clinical features of giant prolactinomas in women. DESIGN:A multicentre, retrospective case series and literature review. METHODS:We collected data from 15 female patients with a pituitary tumour larger than 4 cm and prolactin levels above 1000 μg/l and identified 19 similar case...

journal_title：European journal of endocrinology

authors： Delgrange E,Raverot G,Bex M,Burman P,Decoudier B,Devuyst F,Feldt-Rasmussen U,Andersen M,Maiter D

更新日期：2013-11-22 00:00:00

abstract：OBJECTIVE:Changes in many gastrointestinal peptides, including the anorexigenic peptide YY (PYY), which is produced by L cells, occur in both anorexia nervosa (AN) and obesity (OB). High PYY levels are present in AN, whereas in morbid OB fasting and postprandial PYY secretion is blunted. Somatostatin (somatotropin rele...

journal_title：European journal of endocrinology

authors： Rigamonti AE,Cella SG,Bonomo SM,Mancia G,Grassi G,Perotti M,Agosti F,Sartorio A,Müller EE,Pincelli AI

更新日期：2011-09-01 00:00:00

abstract：Context:The human adrenal is the dominant source of androgens in castration-resistant prostate cancer (CRPC) and classic 21-hydroxylase deficiency (21OHD). Abiraterone, derived from the prodrug abiraterone acetate (AA), inhibits the activity of cytochrome P450 17-hydroxylase/17,20-lyase (CYP17A1), the enzyme required f...

journal_title：European journal of endocrinology

authors： Wright C,O'Day P,Alyamani M,Sharifi N,Auchus RJ

更新日期：2020-04-01 00:00:00

abstract：:We here investigate the potential rescue of the relative hyposomatotropism of aging and obesity by 3-day pulsatile GHRH infusions (i.v. bolus 0.33 microg/kg every 90 min) in 19 healthy men of varying ages (18 to 66 years) and body compositions (12 to 37% total body fat). Baseline (control) and GHRH-driven pulsatile GH...

journal_title：European journal of endocrinology

authors： Iranmanesh A,South S,Liem AY,Clemmons D,Thorner MO,Weltman A,Veldhuis JD

更新日期：1998-07-01 00:00:00

abstract：:Ionomycin, which mobilizes Ca2+, and phorbol 12-myristate 13-acetate (PMA), which activates protein kinase C (PKC), were used to compare the effects/interactions of Ca2+ and PKC on luteinizing hormone (LH) secretion from pituitaries of intact male and acutely ovariectomized (72 h) rats. Quartered pituitaries from dono...

journal_title：European journal of endocrinology

authors： Das S,Fahmy NW,Bourne GA

更新日期：1994-02-01 00:00:00

abstract：:The human growth hormone variant (GH-V) gene is expressed during pregnancy in the syncytiotrophoblast and, as shown recently, in the normal human testis. In addition to the classical transcript encoding for the 22 K major form, intron D-retaining processed mRNAs (GH-V2) have also been described in both tissues. In the...

journal_title：European journal of endocrinology

authors： Untergasser G,Hermann M,Rumpold H,Berger P

更新日期：1998-10-01 00:00:00

abstract：OBJECTIVE:According to the 2015 American Thyroid Association (ATA) guidelines, thyroid ablation by iodine-131 (I-131) therapy is absolutely recommended only in patients with high-risk differentiated thyroid cancer (DTC). Often distant metastases are not recognized early and they can stay silent for long time. The aim o...

journal_title：European journal of endocrinology

authors： Albano D,Bertagna F,Bonacina M,Durmo R,Cerudelli E,Gazzilli M,Panarotto MB,Formenti AM,Mazziotti G,Giustina A,Giubbini R

更新日期：2018-09-01 00:00:00

abstract：:Paragangliomas (PGLs) are rare vascular, neuroendocrine tumors of paraganglia, which are associated with either sympathetic tissue in adrenal (pheochromocytomas (PCCs)) and extraadrenal (sympathetic paraganglioma (sPGLs)) locations or parasympathetic tissue of the head and neck paragangliomas (HNPGLs). As HNPGLs are u...

journal_title：European journal of endocrinology

authors： Corssmit EP,Romijn JA

更新日期：2014-12-01 00:00:00

abstract：:We examined excretion of urinary insulin-like growth factors I and II (IGF-I and IGF-II) and their major binding protein IGFBP-3 in comparison to their respective serum concentration in nine healthy female volunteers (median age 25 years, range 22-27) under baseline conditions and after stimulation with recombinant hu...

journal_title：European journal of endocrinology

authors： Tönshoff B,Blum WF,Vickers M,Kurilenko S,Mehls O,Ritz E

更新日期：1995-04-01 00:00:00

abstract：BACKGROUND:Glucocorticoids are the mainstay of immunosuppression for active moderate-severe Graves' orbitopathy (GO). AIM:To analyze the response to therapy and the contribution of glucocorticoid receptor (GR) gene polymorphisms to the therapeutic outcome of intravenous glucocorticoids (IVGC) in active moderate-severe...

journal_title：European journal of endocrinology

authors： Vannucchi G,Covelli D,Campi I,Origo D,Currò N,Cirello V,Dazzi D,Beck-Peccoz P,Salvi M

更新日期：2013-11-22 00:00:00

abstract：OBJECTIVE:Cushing's disease (CD) is usually caused by ACTH-secreting pituitary microadenomas, while silent corticotroph adenomas (SCA) are macroadenomas without Cushingoid features. However, the molecular mechanism(s) underlying their different tumor growth remains unknown. The aim of the current study was to evaluate ...

journal_title：European journal of endocrinology

authors： Tani Y,Inoshita N,Sugiyama T,Kato M,Yamada S,Shichiri M,Hirata Y

更新日期：2010-10-01 00:00:00