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Usefulness of Polarization-sensitive Optical Coherence Tomography-derived Attenuation-coefficient Images to Visualize the Internal Structure of the Filtering Bleb.

Abstract：

PURPOSE/AIM OF THE STUDY:Polarization-sensitive anterior-segmental optical coherence tomography (PS-OCT) is useful to evaluate the filtering blebs after trabeculectomy. However, the attenuation phenomenon of OCT signal disturbs the visibility of intra-bleb's structure and distribution of birefringence; a specific parameter of PS-OCT. This study aimed to evaluate the effectiveness of the attenuation-coefficient image of the filtering blebs. MATERIALS AND METHODS:This study included 25 eyes 6 months after TLE. The attenuation-coefficient image of blebs was calculated from OCT intensity signal information. The contrast level of the image (reflectivity of bleb's surface wall/reflectivity of scleral flap) in both attenuation-coefficient image and intensity image and the height of the bleb's wall were calculated. The improvement extent of contrast was defined as the ratio of contrast (attenuation-coefficient image's contrast/intensity image's contrast). We compared the contrast of attenuation-coefficient image and intensity image and investigated the relationship between improvement extent of contrast and height of bleb's wall. RESULTS:The contrast of the attenuation-coefficient image (317.7 ± 255.4%) was significantly higher than that of the intensity image (39.1 ± 24.5%) (P < .01) and the improvement extent of contrast was 9.5 ± 4.6 times. Furthermore, there was a positive correlation between the improvement extent of contrast and the height of the bleb's wall (r = 0.44, P = .03). CONCLUSIONS:The contrast of the image at depth of filtering blebs was improved by attenuation-coefficient image. It is suggested that the attenuation-coefficient image may improve the visibility of the structure and distribution of birefringence in the blebs compared to the intensity image.

journal_name

Curr Eye Res

journal_title

Current eye research

authors

Kosugi M,Kokubun T,Tsuda S,Yamanari M,Nakazawa T

doi

10.1080/02713683.2020.1825749

subject

Has Abstract

pub_date

2020-10-04 00:00:00

pages

1-4

eissn

0271-3683

issn

1460-2202

pub_type

杂志文章

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Usefulness of Polarization-sensitive Optical Coherence Tomography-derived Attenuation-coefficient Images to Visualize the Internal Structure of the Filtering Bleb.