Nonpalpable prostate cancer: detection with MR imaging.

Abstract:

:The pathologic specimens and magnetic resonance (MR) images of 53 patients with clinically palpable prostate cancer confined to one lobe were studied to evaluate the ability of MR imaging to depict clinically nonpalpable prostate cancer. All patients had undergone imaging with a 1.5-T imager with T1- and T2-weighted sequences in both axial and sagittal planes before undergoing radical retropubic prostatectomy. At pathologic examination, only the palpable tumor was present in 30 of the 53 patients (57%), and 33 unsuspected tumors were present in an area distinct from the palpable tumor in 23 of the patients (43%). MR imaging successfully depicted 51 palpable tumors for a sensitivity of 96% and 19 of the 33 unsuspected tumors for a sensitivity of 58%. The sensitivity of MR imaging in the detection of nonpalpable, posteriorly located tumors was greater than for those located anteriorly (85% vs 15%). MR imaging was false-positive for nonpalpable tumor in 17 of 30 patients for a specificity of 43%. On the basis of these data, MR imaging has greater sensitivity in the depiction of posteriorly located cancer and is limited by a high false-positive rate in the depiction of nonpalpable tumors.

journal_name

Radiology

journal_title

Radiology

authors

Carter HB,Brem RF,Tempany CM,Yang A,Epstein JI,Walsh PC,Zerhouni EA

doi

10.1148/radiology.178.2.1987620

subject

Has Abstract

pub_date

1991-02-01 00:00:00

pages

523-5

issue

2

eissn

0033-8419

issn

1527-1315

journal_volume

178

pub_type

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