Higher pneumococcal disease vaccination rates needed to protect more at-risk US adults.

Abstract:

:Pneumococcal disease, which includes pneumococcal pneumonia, meningitis, and bacteremia, is associated with substantial morbidity, mortality, and health care costs in adults. Advanced age, chronic lung or cardiovascular disease, immunosuppressive conditions, and smoking increase the risk for infection. Despite the availability of an effective pneumococcal polysaccharide vaccine (PPSV23), vaccination rates among adults remain suboptimal. This is of immediate concern given the current H1N1 pandemic, since secondary bacterial infection with Streptococcus pneumoniae is common and can contribute to morbidity and mortality. The Centers for Disease Control and Prevention has recently called for increased efforts to vaccinate recommended persons against pneumococcal disease. Long-term trends including the growth of the elderly population and an increase in the number of patients with chronic conditions also underscore the importance of improving pneumococcal vaccination rates. It is important for health care providers, public health officials, and policy makers to recognize the serious health impact of pneumococcal disease in adults and to ensure increased coverage; at present, this is the best way to protect against invasive pneumococcal infection and its consequences.

journal_name

Postgrad Med

journal_title

Postgraduate medicine

authors

Rehm SJ,Farley MM,File TM Jr,Hall WJ,Hopkins R,Levine OS,Nichol KL,Nuorti P,Zimmerman RK,Schaffner W

doi

10.3810/pgm.2009.11.2069

subject

Has Abstract

pub_date

2009-11-01 00:00:00

pages

101-5

issue

6

eissn

0032-5481

issn

1941-9260

journal_volume

121

pub_type

杂志文章
  • Aggressive systolic blood pressure control in older subjects: benefits and risks.

    abstract::Systolic hypertension, especially isolated systolic hypertension (ISH) is very common in older subjects aged ≥ 65 years and is a major risk factor for cardiovascular disease (CVD), strokes, heart failure (HF) and chronic kidney disease (CKD). It is also, directly and linearly related with these complications irrespect...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.2018.1433434

    authors: Chrysant SG

    更新日期:2018-03-01 00:00:00

  • SGLT2 inhibitors in patients with type 2 diabetes and renal disease: overview of current evidence.

    abstract::Chronic kidney disease (CKD) is a frequent complication of type 2 diabetes mellitus (T2DM) and is associated with poor clinical outcomes, including an increased risk of all-cause and cardiovascular mortality, as well as adverse economic and social effects. Slowing the development and progression of CKD remains an unme...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.2019.1601404

    authors: Davidson JA

    更新日期:2019-05-01 00:00:00

  • Obsessive-compulsive disorder. What to do if you recognize baffling behavior.

    abstract::The prognosis for patients with obsessive-compulsive disorder has improved dramatically in recent years. Primary care physicians, who may be the first healthcare professionals to consult with these patients, can often provide appropriate treatment or therapeutic guidance. Psychiatric consultations and the implementati...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.1999.12.807

    authors: Khouzam HR

    更新日期:1999-12-01 00:00:00

  • Options for painless local anesthesia.

    abstract::Fear of the needle is a real issue with some patients and may be an obstacle to inducing anesthesia before minor surgical procedures are performed. Adults may express this fear verbally or, out of embarrassment, even avoid coming to the physician's office. Children may become intensely anxious and hysterical. In this ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1991.11700843

    authors: Holmes HS

    更新日期:1991-02-15 00:00:00

  • Dipeptidyl peptidase-4 inhibitor use in patients with type 2 diabetes and cardiovascular disease or risk factors.

    abstract:OBJECTIVES:Management of cardiovascular (CV) risk is an essential aspect of diabetes care, and acceptable CV risk is a requirement for antidiabetes medications. Dipeptidyl peptidase-4 (DPP-4) inhibitors effectively reduce glycated hemoglobin, with a low risk of hypoglycemia and weight gain. The purpose of this review i...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.2015.1095616

    authors: Ryan G

    更新日期:2015-01-01 00:00:00

  • Neonatal jaundice: when to treat, when to watch and wait.

    abstract::What clinical circumstances call for aggressive treatment of jaundice in newborns? Is cessation of breast-feeding necessary to help bring down the high bilirubin concentration? When should phototherapy be started--and stopped? The authors address these and other questions in this thorough guide to differential diagnos...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Lasker MR,Holzman IR

    更新日期:1996-03-01 00:00:00

  • Pharmacologic therapy for bronchial asthma.

    abstract::Many drugs with which to treat reversible obstructive airway disease are available. Beta-adrenergic aerosols are the first line of defense; these are followed, when necessary, by either timed-release theophylline or oral beta-adrenergics. Often, a combination of these drugs must be used to achieve effective relief of ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1987.11699911

    authors: O'Loughlin JM

    更新日期:1987-07-01 00:00:00

  • Drug-induced lupus. The list of culprits grows.

    abstract::More than 70 medications have been implicated as a cause of drug-induced lupus. The condition most commonly manifests with arthralgias and fever. The most important laboratory feature is an elevated antinuclear antibody titer, which often corresponds to the presence of antihistone antibodies. Fortunately, the course o...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.1996.09.83

    authors: Rich MW

    更新日期:1996-09-01 00:00:00

  • When epilepsy masquerades as heart disease. Awareness is key to avoiding misdiagnosis.

    abstract::Autonomic neural impulses that accompany discharges during a seizure can cause a variety of cardiac manifestations, including cardiac arrhythmias, sudden death, anginal chest pain, neurogenic pulmonary edema, and symptoms of pheochromocytoma. Either generalized or focal seizures may generate such signs and symptoms. A...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1990.11716430

    authors: Kothari SS

    更新日期:1990-11-01 00:00:00

  • Gastroesophageal reflux.

    abstract::Preview Although heartburn is the most common symptom of gastroesophageal reflux, many patients with reflux have other, more obscure manifestations. Recognition of all potential signs and symptoms of reflux is important for expeditious management. This article focuses on these atypical presentations and discusses how ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1996.11946110

    authors: Barr LL

    更新日期:1996-04-01 00:00:00

  • Practical tips on prescribing home oxygen therapy.

    abstract::Oxygen therapy is tremendously valuable for patients with chronic respiratory insufficiency. A physician's prescription is needed to obtain Medicare, Medicaid, or insurance-company reimbursement, and certain guidelines must be followed: Patients are selected if significant hypoxemia is present, appropriate pharmacolog...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1988.11700464

    authors: Petty TL

    更新日期:1988-11-01 00:00:00

  • Cost-effective laboratory testing.

    abstract::The increased utilization of diagnostic procedures has prompted interest in cost-effective laboratory testing. Clinically useful tests-useful in the sense that the patient benefits-are cost effective. The choice of test(s) is determined by the risks and benefits of proposed management. In practice, the first step in c...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1981.11715687

    authors: Burke MD

    更新日期:1981-02-01 00:00:00

  • Nonalcoholic fatty liver disease: hepatic manifestation of obesity and the metabolic syndrome.

    abstract::Obesity is currently a worldwide epidemic, and will likely only increase in prevalence in the coming years. The incidence of the metabolic syndrome (MetS) seems to be paralleling obesity. The MetS is strongly linked to insulin resistance, abdominal obesity, diabetes mellitus, and dyslipidemia. Nonalcoholic fatty liver...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2008.07.1800

    authors: Boppidi H,Daram SR

    更新日期:2008-07-31 00:00:00

  • Kaiser Permanente's twist on managed care.

    abstract::When many physicians think of managed care, they think first of Kaiser Permanente, the nation's largest HMO. That perception is misguided, according to David M. Lawrence, MD, the chief executive officer and chairman of the boards of the Kaiser Foundation health plan and hospitals. During a phone interview recently, La...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1994.11945854

    authors: Lawrence DM,Stenger A

    更新日期:1994-05-15 00:00:00

  • When to worry about hypoglycemia.

    abstract::The important causes of hypoglycemia unrelated to known diabetes are relatively few. Postprandial hypoglycemia is a relatively benign disorder. Fasting hypoglycemia is more serious and may be caused by metabolic disturbances or tumors. Several hereditary disorders cause hypoglycemia in infants and must be diagnosed an...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.1990.11716369

    authors: Felicetta JV

    更新日期:1990-07-01 00:00:00

  • PDI-4A: an augmented provisional screening instrument assessing 5 additional common anxiety-related diagnoses in adult primary care patients.

    abstract::Patients with nonpsychotic mental health and emotional problems are commonly seen by primary care physicians. The objective of this study was to expand the Provisional Diagnostic Instrument-4 (PDI-4) to include a short self-report screen for 5 common anxiety-related diagnoses: panic attack (PA), social phobia (SP), ob...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.3810/pgm.2011.09.2463

    authors: Houston JP,Kroenke K,Davidson JR,Adler LA,Faries DE,Ahl J,Swindle R,Trzepacz PT

    更新日期:2011-09-01 00:00:00

  • Practical tips for office surgery. Commonsense advice from a plastic surgeon.

    abstract::Performing office surgery well is an art. You can accomplish this by being attentive to several factors. These include, but are not limited to, providing an office environment that is pleasant, restful, and happy; using proper lighting, instruments, and suture techniques; using gentle techniques for local infiltration...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1983.11698400

    authors: Clavin HD

    更新日期:1983-08-01 00:00:00

  • Efficacy and safety of saxagliptin combination therapy in US patients with type 2 diabetes.

    abstract:BACKGROUND:The mechanism of action of dipeptidyl peptidase-4 inhibitors, such as saxagliptin, makes them suitable for combination therapy in type 2 diabetes mellitus (T2DM). Genetic, cultural, and environmental differences in individuals from different regions of the world may result in differences in treatment respons...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.3810/pgm.2011.07.2305

    authors: Karyekar C,Donovan M,Allen E,Fleming D,Ravichandran S,Chen R

    更新日期:2011-07-01 00:00:00

  • Bronchiectasis in adults: a review.

    abstract::Bronchiectasis is characterized by permanent, abnormal dilation of the bronchi with chronic inflammation and infection. Bronchiectasis is either caused by or associated with several systemic disorders, and in a significant number of cases, the underlying etiology remains unidentified and is subsequently referred to as...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2008.09.1912

    authors: Lazarus A,Myers J,Fuhrer G

    更新日期:2008-09-01 00:00:00

  • Effect of early weight loss on type 2 diabetes mellitus after 2 years of gastric banding.

    abstract:OBJECTIVE:Laparoscopic adjustable gastric banding (LAGB) is an established bariatric surgical procedure that produces meaningful weight loss and improvements in patients with type 2 diabetes mellitus (T2DM) and a body mass index (BMI) ≥ 30 kg/m2. This study examined the effect of LAGB on T2DM status in severely obese p...

    journal_title:Postgraduate medicine

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.3810/pgm.2012.11.2590

    authors: Edelman S,Bhoyrul S,Billy H,Cornell C,Okerson T

    更新日期:2012-11-01 00:00:00

  • Surgery in the elderly. Lowering risks by understanding special needs.

    abstract::Elderly patients should be evaluated closely before surgery. Problems commonly found in these patients (ie, hypertension, diabetes, and cardiac and pulmonary disease) should be sought with special care and treated before surgery is undertaken. Also, wound healing may be compromised, drug clearance and metabolism impai...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1992.11701206

    authors: Nolan TE

    更新日期:1992-02-01 00:00:00

  • Comorbidities in patients with irritable bowel syndrome with constipation or chronic idiopathic constipation: a review of the literature from the past decade.

    abstract:BACKGROUND:Irritable bowel syndrome with constipation (IBS-C) and chronic idiopathic constipation (CIC) are common functional bowel disorders. Patients with IBS-C or CIC often present with ≥ 1 comorbidity that coincides with either of these conditions. These comorbidities may make underappreciated contributions to the ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2013.03.2640

    authors: Nellesen D,Chawla A,Oh DL,Weissman T,Lavins BJ,Murray CW

    更新日期:2013-03-01 00:00:00

  • Cancer surveillance. Who stands to benefit?

    abstract::Currently, surveillance or risk-oriented follow-up of patients in the individual practice setting may be the most efficacious means of reducing the morbidity and mortality associated with selected types of cancer. Intervention into carcinogenesis or alteration of the natural history of cancer requires a clear understa...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1985.11699112

    authors: Lamon JM

    更新日期:1985-09-01 00:00:00

  • Cardiovascular risk factors.

    abstract::Preview New information emerges almost weekly about the relative importance of one factor or another in the development of coronary artery disease. Yet controversies continue over which factor deserves the most emphasis. Dr Elliott presents a broad and, at times, humorous look at research into cardiovascular risk fact...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1994.11945892

    authors: Elliott WJ

    更新日期:1994-09-01 00:00:00

  • Symposium. ENT for nonspecialists. The patient has a lump in the neck.

    abstract::When a patient presents with a hard, painless lump in the neck, one should assume that it is a cancer and that it is metastatic from a primary lesion located above the clavicle. A careful physical examination with the appropriate instruments most often will determine the site of the primary lesion. Laryngograms or lat...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1975.11714054

    authors: Devine KD

    更新日期:1975-05-01 00:00:00

  • Gastric volvulus. More common than previously thought?

    abstract::Gastric volvulus is torsion of the stomach, which can compromise the gastric orifices and result in either acute or chronic and intermittent symptoms. We believe that gastric volvulus, especially when partial or intermittent, may be more common than has been previously thought. The condition should be suspected in any...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1986.11699576

    authors: Llaneza PP,Salt WB 2nd

    更新日期:1986-10-01 00:00:00

  • Allergic disease in children. Guide to diagnosis and treatment.

    abstract::Allergy is responsible for many problems in the pediatric age-group. At times the most difficult job for the physician is to determine if the patient is indeed allergic and, if so, to what. Allergy skin testing remains the first choice for diagnostic study. Treatment consists of avoiding the offending allergen if poss...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1984.11716317

    authors: Hein EW,Kishore R

    更新日期:1984-05-01 00:00:00

  • Septic shock. What to do until a breakthrough comes along.

    abstract::Septic shock is a multisystem disorder that represents the host's response to microbial invasion in its most fulminant form. One of the critical defects is a widespread inability to use available substrate for energy production. Endogenous mediators, particularly the cytokines, appear to play an essential role in this...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.1989.11704384

    authors: DePriest JL

    更新日期:1989-09-01 00:00:00

  • Diet and diabetes.

    abstract::Present evidence suggests that the most important nutritional factor bearing on the risk of development of diabetes mellitus is an excessive caloric intake. Other evidence suggests that both dietary prevention of diabetes and mitigation of hyperglycemia by dietary means can prevent morbidity and mortality from the mic...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1976.11712096

    authors: West KM

    更新日期:1976-09-01 00:00:00

  • Angiotensin receptor blocker and dihydropyridine calcium channel blocker combinations: an emerging strategy in hypertension therapy.

    abstract::Hypertension is a leading contributor to the burden of cardiovascular disease. The importance of lowering blood pressure (BP) to reduce the risk of cardiovascular events has been demonstrated in numerous clinical trials. Most patients require combination antihypertensive therapy utilizing agents from complementary dru...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2009.03.1974

    authors: Oparil S,Weber M

    更新日期:2009-03-01 00:00:00