Drug-induced lupus. The list of culprits grows.

Abstract:

:More than 70 medications have been implicated as a cause of drug-induced lupus. The condition most commonly manifests with arthralgias and fever. The most important laboratory feature is an elevated antinuclear antibody titer, which often corresponds to the presence of antihistone antibodies. Fortunately, the course of drug-induced lupus is more benign than that of idiopathic systemic lupus erythematosus. Clinical resolution generally occurs after withdrawal of the offending agent. The patient described here exemplifies the importance of maintaining a heightened awareness of this uncommon disorder. For him, delayed diagnosis of drug-induced lupus resulted in prolonged discomfort, restriction of daily activities, and unnecessary therapeutic intervention.

journal_name

Postgrad Med

journal_title

Postgraduate medicine

authors

Rich MW

doi

10.3810/pgm.1996.09.83

subject

Has Abstract

pub_date

1996-09-01 00:00:00

pages

299-302, 307-8

issue

3

eissn

0032-5481

issn

1941-9260

journal_volume

100

pub_type

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