The two holes syndrome.

abstract：BACKGROUND:Major histocompatibility complex (MHC) class II is involved in T-cell activation, cytokine secretion, and induction of immune responses. Cytokines, staphylococcus super antigens, and eosinophil activation are proposed to play important roles in aspirin-exacerbated respiratory disease (AERD). OBJECTIVES:This...

journal_title：American journal of rhinology & allergy

authors： Esmaeilzadeh H,Nabavi M,Amirzargar AA,Aryan Z,Arshi S,Bemanian MH,Fallahpour M,Mortazavi N,Rezaei N

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Gelsolin is an actin-binding protein with multiple cellular functions including apoptosis and is reported to be down-regulated in various cancers and premalignant lesions. The objective of this study was to identify gelsolin and caspase-3 expression in inverted papilloma (IP) and investigate the role of gels...

journal_title：American journal of rhinology & allergy

authors： Cho JE,Park Wi,Kim DC,Kim HJ,Kim SW,Kang JM,Cho JH

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:A foreign body (FB) penetrating intracranially after passing transorbitally or transnasally is a rare occurrence. However, otolaryngologists are increasingly being asked to participate in the care of these patients for both endoscopic removal of the object and repair of any skull base defects. OBJECTIVE:To ...

journal_title：American journal of rhinology & allergy

authors： Ghadersohi S,Ference EH,Detwiller K,Kern RC

更新日期：2017-03-01 00:00:00

abstract：:Background Head and neck surgical pathology has been shown to be prone to histopathologic diagnostic error that can adversely impact patient care due to inappropriate management. Sinonasal tumors, in particular, present a diagnostic challenge given the relative rarity and diversity in histology and thus may have highe...

journal_title：American journal of rhinology & allergy

authors： Ganti A,Tajudeen BA,Plitt MA,Rossi I,Gattuso P,Batra PS

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:CD203c is a basophil surface marker and its expression is rapidly up-regulated after cross-linking of high-affinity immunoglobulin E (IgE) receptor (FcepsilonR1) by an allergen. CD203c basophil activation tests have been studied for the in vitro diagnosis of several allergic conditions. However, there is li...

journal_title：American journal of rhinology & allergy

authors： Özdemir SK,Güloğlu D,Sin BA,Elhan AH,Ikincioğulları A,Mısırlıgil Z

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Conclusive evidence exists that biofilms are present on the mucosa of chronic rhinosinusitis (CRS) patients. Less is known about the species constituting these biofilms. This study developed a fluorescence in situ hybridization (FISH) protocol for characterization of bacterial and fungal biofilms in CRS. ME...

journal_title：American journal of rhinology & allergy

authors： Foreman A,Psaltis AJ,Tan LW,Wormald PJ

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Oxidative stress may play a role in the pathophysiology of several diseases including allergic rhinitis (AR). In children with AR an antioxidant enzyme paraoxonase (PON1) has not been previously investigated. The aim of this study was to investigate plasma PON1 activity and plasma total oxidant status (TOS)...

journal_title：American journal of rhinology & allergy

authors： Ozkaya E,Akduman H,Erenberk U,Demir A,Dundaroz MR

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Internal nasal valve collapse is a preventable complication of rhinoplasty, for which the spreader graft is the gold standard. More recently, the spreader flap technique has been espoused as an alternative to spreader grafting. Here, we evaluated the efficacy of this technique in a randomized trial setting. ...

journal_title：American journal of rhinology & allergy

authors： Saedi B,Amali A,Gharavis V,Yekta BG,Most SP

更新日期：2014-01-01 00:00:00

abstract：INTRODUCTION:Accountable care organizations (ACO) and alternative payment models are a sign of the change in reimbursement from fee-for-service to value-based reimbursement. The focus of health care under ACOs is represented by the Triple Aim: to improve the experience of health care, improve the health of populations,...

journal_title：American journal of rhinology & allergy

authors： Barry JY,McCrary HC,Kent S,Saleh AA,Chang EH,Chiu AG

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:B-cell responses may play a role in the pathogenesis of nasal polyposis via local IgA and IgE production and activation of eosinophils and mast cells. B-cell attracting chemokines may therefore have relevance in the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNPs) Methods: Polyp and inferio...

journal_title：American journal of rhinology & allergy

authors： Patadia M,Dixon J,Conley D,Chandra R,Peters A,Suh LA,Kato A,Carter R,Harris K,Grammer L,Kern R,Schleimer R

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Assessing surgical competency in otolaryngology is challenging, and residency programs are now responsible for ensuring the surgical competency of their graduates. Therefore, more objective assessment tools are being incorporated into the evaluation process. Objective structured assessment of technical skill...

journal_title：American journal of rhinology & allergy

authors： Obeid AA,Al-Qahtani KH,Ashraf M,Alghamdi FR,Marglani O,Alherabi A

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:The effect of crenotherapy on major mucosal markers of inflammation, TNF alpha, human beta-defensins 2 (hBD-2), and calprotectin, are largely unexplored in pediatric chronic rhinosinusitis (CRS). The aim of this study was to investigate the effects of crenotherapy with sulfate-sodium-chloride water on mucos...

journal_title：American journal of rhinology & allergy

authors： Passariello A,Di Costanzo M,Terrin G,Iannotti A,Buono P,Balestrieri U,Balestrieri G,Ascione E,Pedata M,Canani FB,Canani RB

更新日期：2012-01-01 00:00:00

abstract：INTRODUCTION:Criterion standard treatment of allergic fungal sinusitis (AFS) is primary surgery followed by adjuvant therapy. Even after good surgery, recurrence rates vary from 10 to 79%. Antifungals, e.g., itraconazole, and steroids have shown varying success rates in delaying recurrences given after surgery. Itracon...

journal_title：American journal of rhinology & allergy

authors： Patro SK,Verma RK,Panda NK,Chakrabarti A,Singh P

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Respiratory epithelial adenomatoid hamartomas (REAH) are benign nose neoplasms found in the nasal cavity and sinuses. Symptoms include anosmia, nasal obstruction, facial pressure, and rhinorrhea. Although previously thought to be rare, these tumors are being increasingly recognized on pathology in patients u...

journal_title：American journal of rhinology & allergy

authors： Davison WL,Pearlman AN,Donatelli LA,Conley LM

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Cigarette smoke exposure (CSE) results in extensive inflammation in the upper and lower airways. Reactive oxygen species, such as superoxide, have been shown to be potent mediators of this inflammation. METHODS:Mucosal biopsy specimens were collected from patients undergoing sinonasal surgery and were used ...

journal_title：American journal of rhinology & allergy

authors： Mulligan RM,Atkinson C,Vertegel AA,Reukov V,Schlosser RJ

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Liquid-based cytology (LBC) has achieved great success in cytological diagnosis of various cancers when compared with conventional smear methods. However, its application in diagnosing nasopharyngeal carcinoma (NPC) has never been studied. METHODS:Eighty-four consecutive patients who underwent nasopharyngea...

journal_title：American journal of rhinology & allergy

authors： Jan YJ,Chen SJ,Wang J,Jiang RS

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Surgery for chronic rhinosinusitis with nasal polyps (CRSwNPs) often fails because of recurrence of disease. So far, we do not know if specific cytokine profiles are linked to recurrence after functional endoscopic sinus surgery (FESS) or can predict recurrence. In this study we investigate the cytokine prof...

journal_title：American journal of rhinology & allergy

authors： Van Zele T,Holtappels G,Gevaert P,Bachert C

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Sex hormones are known to have some influence on nasal functions, but their effect on the decongestive response of the nasal mucosa during menstrual cycle is still undetermined. OBJECTIVES:The aim of this study was to examine the nasal physiology, the interconnectedness of olfactory and respiratory nasal fu...

journal_title：American journal of rhinology & allergy

authors： Bogdan MS,Slavic DO,Babovic SS,Zvezdin BS,Kolarov VP,Kljajic VL

更新日期：2021-01-26 00:00:00

abstract：BACKGROUND:Patients report that nasal congestion is the most bothersome symptom of allergic rhinitis (AR). Recently, a short, patient-reported congestion screener questionnaire, the Congestion Quantifier Seven-Item Test (CQ7), was developed to identify a level of congestion that may warrant patients seeking evaluation ...

journal_title：American journal of rhinology & allergy

authors： Stull DE,Meltzer EO,Krouse JH,Roberts L,Kim S,Frank L,Naclerio R,Lund V,Long A

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Aspirin-exacerbated respiratory disease (AERD) affects 7% of asthmatics. Usual therapies are inadequate for asthma and/or nasal polyposis, leading to decreased quality of life. OBJECTIVE:Our objective was to evaluate the efficacy of dupilumab in AERD patients with uncontrolled, chronic rhinosinusitis with n...

journal_title：American journal of rhinology & allergy

authors： Mustafa SS,Vadamalai K,Scott B,Ramsey A

更新日期：2020-09-23 00:00:00

abstract：BACKGROUND:There is a correlation between (18)F-fluorodeoxyglucose (FDG) uptake and the level of intracellular metabolic tumor activity, which in turn may be associated with active proliferation, invasion, and prognosis as well as distant metastases in head and neck cancer. This study was designed to assess whether tum...

journal_title：American journal of rhinology & allergy

authors： Seol JH,Kim J,Lee JD,Lee JG,Yoon JH,Kim CH

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Platelet-activating factor (PAF) is a lipid mediator produced by most inflammatory cells. Clinical and experimental findings suggest that PAF participates in allergic rhinitis (AR) pathogenesis. The aim was to assess the PAF ability to induce clinical response in nasal airway after local stimulation. METHOD...

journal_title：American journal of rhinology & allergy

authors： Muñoz-Cano R,Valero A,Roca-Ferrer J,Bartra J,Sanchez-Lopez J,Mullol J,Picado C

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:This study was designed to determine if the addition of large-volume, low-positive pressure nasal irrigations delivered with isotonic sodium chloride (hereinafter "saline") added to intranasal corticosteroid therapy improves quality of life and objective measures of nasal breathing in patients with allergic ...

journal_title：American journal of rhinology & allergy

authors： Nguyen SA,Psaltis AJ,Schlosser RJ

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Giant frontal mucoceles, characterized by significant intracranial and/or intraorbital extension, can present with significant neurologic symptoms. Although typical mucoceles are managed endoscopically, giant mucoceles are often treated with an open or combined approach due to various concerns, including fro...

journal_title：American journal of rhinology & allergy

authors： Stokken J,Wali E,Woodard T,Recinos PF,Sindwani R

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Visual Analog Scale (VAS) as determined by the patient is recommended by the European Position Paper on Rhinosinusitis and Nasal Polyps 2012 in evaluation of the total severity of the chronic rhinosinusitis (CRS) patients' symptoms. OBJECTIVE:To evaluate the correlation between evaluations performed by otor...

journal_title：American journal of rhinology & allergy

authors： Zhao L,Yu KN,Tan JL,Zhang HL,Jin P,Zi XX,Tu YY,Li T,Zhou XM,Shi L,Wang Y

更新日期：2020-11-01 00:00:00

abstract：:Background Since the Food and Drug Administration approval of balloon sinuplasty (BSP) in 2005, no nationally representative population-based studies have examined the outcomes and adverse events of BSP. Objective To assess the rates of complications and revision surgery in patients who received BSP, functional endosc...

journal_title：American journal of rhinology & allergy

authors： Chaaban MR,Rana N,Baillargeon J,Baillargeon G,Resto V,Kuo YF

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVES:Inadvertent intracranial injury from nasogastric tube (NGT) placement is a described and potentially fatal complication following endoscopic transsphenoidal hypophysectomy (TSH). This cadaver study assessed the role of middle turbinate (MT) preservation and medialization in preventing accidental skull base i...

journal_title：American journal of rhinology & allergy

authors： Shah J,Tang D,Grafmiller K,Cappello ZJ,Roxbury C,Sindwani R

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to investigate the expression and distribution of superoxide anion, NADPH oxidase (NOX)1, and NOX4 in healthy, allergic nasal mucosa and nasal polyps to evaluate the possible influence of oxidative stress on the development of allergic rhinitis and nasal polyps. METHODS:The exp...

journal_title：American journal of rhinology & allergy

authors： Moon JH,Kim TH,Lee HM,Lee SH,Choe W,Kim HK,Lee JH,Oh KH,Lee SH

更新日期：2009-07-01 00:00:00

abstract：PURPOSE:To evaluate the role of allergen immunotherapy (AIT) in the treatment of allergic rhinitis (AR). METHOD:Individual studies, systematic reviews, and practice guidelines that included information on sublingual AIT (SLIT) and subcutaneous AIT (SCIT) in the treatment of AR were considered. RESULTS:AIT via the SLI...

journal_title：American journal of rhinology & allergy

authors： Cox L

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Volumetric analysis of the olfactory cleft by using computed tomography has been associated with olfaction in patients with chronic rhinosinusitis (CRS). However, existing studies have not comprehensively measured olfaction, and it thus remains unknown whether correlations differ across specific dimensions o...

journal_title：American journal of rhinology & allergy

authors： Kohli P,Schlosser RJ,Storck K,Soler ZM

更新日期：2016-11-01 00:00:00