Abstract:
BACKGROUND:A foreign body (FB) penetrating intracranially after passing transorbitally or transnasally is a rare occurrence. However, otolaryngologists are increasingly being asked to participate in the care of these patients for both endoscopic removal of the object and repair of any skull base defects. OBJECTIVE:To assess the presentation, workup, and management of transnasal or transorbital penetrating FB injury. METHODS:Systematic review of the presentation, workup, and management of transnasal or transorbital penetrating FB injury; plus, a case report of a 53-year-old woman with a transorbital penetrating rose bush branch. We searched medical literature data bases, which resulted in 215 total titles, which were then narrowed based on inclusion and exclusion criteria. RESULTS:Thirty-five cases of transorbital or transnasal low-velocity trauma that involved the paranasal sinuses were reviewed from 33 articles. The average age was 30 years, 40% of the objects were made of wood. Fifty-seven percent of the cases were transorbital, whereas 43% were transnasal. Forty-six percent of the surgical interventions were completed endoscopically or with endoscopic assistance. Complications of injury were common, with 66% of patients experiencing cerebrospinal fluid leaks; 23%, permanent blindness; 17%, meningitis; 14%, ophthalmoplegia; 9%, decreased visual acuity; and 3%, brain abscess. Our patient presented with a traumatic cerebrospinal fluid leak, and recovered well after transorbital and endoscopic removal of the branch, skull base repair, and a prolonged course of antibiotics and antifungal medications. CONCLUSIONS:Transnasal and transorbital penetrating FB injuries are a relatively uncommon occurrence but when they do occur require rapid workup and interdisciplinary management to prevent acute and delayed complications.
journal_name
Am J Rhinol Allergyjournal_title
American journal of rhinology & allergyauthors
Ghadersohi S,Ference EH,Detwiller K,Kern RCdoi
10.2500/ajra.2017.31.4421subject
Has Abstractpub_date
2017-03-01 00:00:00pages
29-34issue
2eissn
1945-8924issn
1945-8932journal_volume
31pub_type
杂志文章,评审abstract:BACKGROUND:The impact of middle turbinate resection (MTR) on olfaction remains a point of debate in the current literature. Few studies have objectively evaluated olfactory cleft airflow following MTR; thus, the mechanism by which MTR may impact olfaction is poorly understood. It is not known whether the postsurgical c...
journal_title:American journal of rhinology & allergy
pub_type: 杂志文章
doi:10.1177/1945892418816841
更新日期:2019-05-01 00:00:00
abstract::Background Head and neck surgical pathology has been shown to be prone to histopathologic diagnostic error that can adversely impact patient care due to inappropriate management. Sinonasal tumors, in particular, present a diagnostic challenge given the relative rarity and diversity in histology and thus may have highe...
journal_title:American journal of rhinology & allergy
pub_type: 杂志文章
doi:10.1177/1945892418762845
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:Viral respiratory tract infections are associated with a significant burden of disease and represent one of the leading causes of mortality worldwide. The current Coronavirus Disease 2019 (COVID-19) pandemic highlights the devastating toll that respiratory viruses have on humanity and the desperate need to u...
journal_title:American journal of rhinology & allergy
pub_type: 杂志文章,评审
doi:10.1177/1945892420947929
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:The clinical importance of serum squamous cell carcinoma antigen (SCCA) and SCCA subclasses has not been established for treating inverted papilloma (IP). The aim of this study was to clarify the clinical importance of serum SCCA and its subclasses in IP, compared with maxillary squamous cell carcinoma and ...
journal_title:American journal of rhinology & allergy
pub_type: 杂志文章
doi:10.2500/ajra.2012.26.3797
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:Epiphora has a significant impact on the patient's quality of life and is commonly caused by nasolacrimal duct obstruction. Dacryocystorhinostomy (DCR) has traditionally been performed via an external approach, which involves a skin incision. With the advent of endoscopes, the endonasal approach to DCR has g...
journal_title:American journal of rhinology & allergy
pub_type: 杂志文章
doi:10.2500/ajra.2018.32.4494
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Silastic splints have been used as effective tools for septal support, avoiding adhesion, and mucosal healing after septal surgery. Furthermore, although many surgeons insert septal splints, no well-designed trials exist to support their use. A randomized double-blinded controlled trial was performed. METHO...
journal_title:American journal of rhinology & allergy
pub_type: 杂志文章,随机对照试验
doi:10.2500/ajra.2011.25.3584
更新日期:2011-05-01 00:00:00
abstract:BACKGROUND:A 10- to 15-mm L-strut in the dorsal and caudal areas of the nasal septum is preserved during septoplasty to maintain structural stability and prevent external deformity. However, during endoscopically performed septoplasty the surgeon has a very different perspective, which may create a more challenging sit...
journal_title:American journal of rhinology & allergy
pub_type: 杂志文章
doi:10.2500/ajra.2014.28.4042
更新日期:2014-05-01 00:00:00
abstract:BACKGROUND:Gelsolin is an actin-binding protein with multiple cellular functions including apoptosis and is reported to be down-regulated in various cancers and premalignant lesions. The objective of this study was to identify gelsolin and caspase-3 expression in inverted papilloma (IP) and investigate the role of gels...
journal_title:American journal of rhinology & allergy
pub_type: 杂志文章
doi:10.2500/ajra.2012.26.3753
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:Chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) and asthma are strongly associated, and patients suffering from both diseases are often difficult to treat. However, no guidelines about the management of patients with CRS and coexisting asthma exist. OBJECTIVE:The purpose of this systematic review wa...
journal_title:American journal of rhinology & allergy
pub_type: 杂志文章,评审
doi:10.2500/ajra.2015.29.4178
更新日期:2015-05-01 00:00:00
abstract:PURPOSE:Activation of adenosine monophosphate-activated protein kinase (AMPK) by metformin, as a master regulator of metabolism, is involved in airway tissue remodeling. Here, we investigated the physical role of AMPK on cell migration, matrix contraction, and the production of matrix metalloproteinases (MMP) in nasal ...
journal_title:American journal of rhinology & allergy
pub_type: 杂志文章
doi:10.2500/ajra.2017.31.4477
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVES:Identification of the most common aeroallergens to which patients are sensitized in a specific area is important in the diagnosis and treatment of allergic rhinitis (AR). We determined the distribution of aeroallergens, detected by skin-prick tests (SPT), in adult patients with AR in the Eastern Black Sea re...
journal_title:American journal of rhinology & allergy
pub_type: 杂志文章
doi:10.2500/ajra.2016.30.4353
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:The extent of surgery required in the management of pediatric non-medial subperiosteal orbital abscess (SPOA) due to medically refractory complicated acute sinusitis is unknown. OBJECTIVES:The primary objective is to compare operative outcomes of children treated with combined endoscopic sinus surgery (ESS)...
journal_title:American journal of rhinology & allergy
pub_type: 杂志文章
doi:10.1177/1945892420953790
更新日期:2020-08-25 00:00:00
abstract:BACKGROUND:Chronic rhinitis impacts 60 million Americans and is associated with significant costs for patients. Although medical treatments are first line, some patients require surgical intervention such as vidian or posterial nasal neurectomy. Previous reviews have investigated the role of surgical management in chro...
journal_title:American journal of rhinology & allergy
pub_type: 杂志文章
doi:10.1177/1945892418800879
更新日期:2018-11-01 00:00:00
abstract:PURPOSE:To assess the efficacy and safety of bupivacaine compared with lidocaine in local anesthesia of nasopharynx through meta-analysis. METHODS:A number of medical literature data bases were searched electronically. Relevant journals and references of included studies were manually searched. Two reviewers independe...
journal_title:American journal of rhinology & allergy
pub_type: 杂志文章,meta分析
doi:10.2500/ajra.2016.30.4357
更新日期:2016-09-30 00:00:00
abstract:BACKGROUND:Over the past 10 years, the management of juvenile nasopharyngeal angiofibroma (JNA) has been redefined because of the improvement of transnasal skull base techniques. However, the limits of endoscopic resection still have to be fully defined. The purpose of this study was to report on a series of patients p...
journal_title:American journal of rhinology & allergy
pub_type: 杂志文章
doi:10.2500/ajra.2009.23.3322
更新日期:2009-05-01 00:00:00
abstract:BACKGROUND:Respiratory epithelial adenomatoid hamartomas (REAH) are benign nose neoplasms found in the nasal cavity and sinuses. Symptoms include anosmia, nasal obstruction, facial pressure, and rhinorrhea. Although previously thought to be rare, these tumors are being increasingly recognized on pathology in patients u...
journal_title:American journal of rhinology & allergy
pub_type: 杂志文章
doi:10.2500/ajra.2016.30.4338
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:Patients report nasal congestion as the most bothersome seasonal allergic rhinitis (SAR) symptom. Measurement of this symptom in previous research has largely been based on subjective patient ratings. This study was designed to measure efficacy, onset, and duration of action of the corticosteroid mometasone ...
journal_title:American journal of rhinology & allergy
pub_type: 杂志文章,随机对照试验
doi:10.2500/ajra.2010.24.3548
更新日期:2010-11-01 00:00:00
abstract:BACKGROUND:CD203c is a basophil surface marker and its expression is rapidly up-regulated after cross-linking of high-affinity immunoglobulin E (IgE) receptor (FcepsilonR1) by an allergen. CD203c basophil activation tests have been studied for the in vitro diagnosis of several allergic conditions. However, there is li...
journal_title:American journal of rhinology & allergy
pub_type: 杂志文章
doi:10.2500/ajra.2011.25.3723
更新日期:2011-11-01 00:00:00
abstract:BACKGROUND:Skin prick test (SPT) or Phadiatop, a multi-allergen IgE screening test, was used as a tool for detecting aeroallergen sensitization. OBJECTIVE:To compare SPT and Phadiatop as a tool for diagnosis allergic rhinitis (AR) using the nasal provocation test (NPT) as a comparative standard. METHODS:Children aged...
journal_title:American journal of rhinology & allergy
pub_type: 杂志文章
doi:10.1177/1945892420938300
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:A number of studies suggested that limited economical airborne allergy screening can successfully predict true respiratory allergy and be of use to primary care providers (PCPs) in improving the accuracy of their differential diagnosis and treatment of allergic rhinitis. More accurate diagnosis would lead to...
journal_title:American journal of rhinology & allergy
pub_type: 杂志文章
doi:10.2500/ajra.2012.26.3764
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:Specific antibody deficiency may predispose patients to recurrent respiratory tract infections. There is limited literature assessing specific antibody deficiency in chronic rhinosinusitis (CRS). This study evaluated the role of specific antibody deficiency in patients with CRS who have failed medical therap...
journal_title:American journal of rhinology & allergy
pub_type: 杂志文章
doi:10.2500/ajra.2011.25.3653
更新日期:2011-07-01 00:00:00
abstract:BACKGROUND:Spontaneous cerebrospinal fluid (CSF) leaks are largely attributed to idiopathic intracranial hypertension and typically present as skull base defects with or without prolapse of intracranial contents. However, in our practice, we have encountered a distinct type of spontaneous CSF leak that presents in a di...
journal_title:American journal of rhinology & allergy
pub_type: 杂志文章
doi:10.2500/ajra.2017.31.4413
更新日期:2017-03-01 00:00:00
abstract:BACKGROUND:Allergic rhinitis is commonly treated with antihistamines. Monitoring improvement of airway inflammation noninvasively using nasal nitric oxide (nNO) would be clinically useful. To determine the anti-inflammatory effect of oral levocetirizine dihydrochloride (LC), we measured nNO and nasal eosinophils (nEos...
journal_title:American journal of rhinology & allergy
pub_type: 杂志文章,随机对照试验
doi:10.2500/ajra.2011.25.3668
更新日期:2011-11-01 00:00:00
abstract:BACKGROUND:The association between olfactory dysfunction (OD) and cognitive decline is becoming apparent in the emerging literature. However, the literature demonstrating a similar effect between gustatory dysfunction (GD) and cognition is not well established. OBJECTIVE:To determine whether OD and GD are independentl...
journal_title:American journal of rhinology & allergy
pub_type: 杂志文章
doi:10.1177/1945892418824451
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:Fibrin glue has been a favorable hydrogel in cartilage tissue engineering, but implantation of chondrocyte-fibrin suspensions have resulted in volume loss. In this study, human septal cartilage chips were seeded onto a fibrin scaffold, and cellular proliferation and production of cartilaginous extracellular ...
journal_title:American journal of rhinology & allergy
pub_type: 杂志文章
doi:10.2500/ajra.2009.23.3347
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND:Multiple methods exist for nasal septoplasty. Proliferation of endoscopic technology has broadened these options. METHODS:Technical description of two techniques for endoscopic septoplasty. RESULTS:The endoscope can be utilized for visualization under the flaps after, a Killian or hemitransfixion incision,...
journal_title:American journal of rhinology & allergy
pub_type: 杂志文章
doi:10.2500/ajra.2017.31.4436
更新日期:2017-07-01 00:00:00
abstract:BACKGROUND:Although nasal steroids are the mainstay treatments in nasal polyposis, up to one-half of patients do not respond and need surgical treatment. This study aimed to evaluate whether oxymetazoline administration produces any additive effect on nasal steroid therapy and whether rebound congestion develops after ...
journal_title:American journal of rhinology & allergy
pub_type: 杂志文章,随机对照试验
doi:10.2500/ajra.2016.30.4294
更新日期:2016-05-01 00:00:00
abstract::Background Retronasal olfaction is important in flavor detection and enjoyment. The ability to identify specific individual retronasal odors may play a role in quality of life for patients with chronic rhinosinusitis (CRS). Objective To identify patterns and improve understanding of retronasal identification of indivi...
journal_title:American journal of rhinology & allergy
pub_type: 杂志文章
doi:10.1177/1945892418793540
更新日期:2018-09-01 00:00:00
abstract::Surgery for chronic rhinosinusitis is an effective complement to a well-designed medical regimen. Functional endoscopic sinus surgery is among the most common surgeries performed for sinonasal disease refractory to maximal medical therapy. Nasal surgery techniques, such as septoplasty and inferior turbinate surgery, m...
journal_title:American journal of rhinology & allergy
pub_type: 杂志文章,评审
doi:10.2500/ajra.2013.27.3897
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND:Nasal polyposis represents the end point of multiple inflammatory pathways and controversy continues as to the exact roles of medical and surgical approaches in the management of nasal polyposis. METHODS:A combination of both is often required to manage polyps adequately with surgery and intranasal steroids...
journal_title:American journal of rhinology & allergy
pub_type: 杂志文章,评审
doi:10.2500/ajra.2011.25.3681
更新日期:2011-09-01 00:00:00