Crenotherapy modulates the expression of proinflammatory cytokines and immunoregulatory peptides in nasal secretions of children with chronic rhinosinusitis.

abstract：BACKGROUND:The clinical importance of serum squamous cell carcinoma antigen (SCCA) and SCCA subclasses has not been established for treating inverted papilloma (IP). The aim of this study was to clarify the clinical importance of serum SCCA and its subclasses in IP, compared with maxillary squamous cell carcinoma and ...

journal_title：American journal of rhinology & allergy

authors： Suzuki M,Deng Z,Hasegawa M,Uehara T,Kiyuna A,Maeda H

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Biofilm formation has been implicated as an etiologic factor in the development of chronic rhinosinusitis (CRS). Nasal irrigation with surfactants including dilute baby shampoo have been proposed as an antibiofilm treatment for CRS patients. The effect of dilute baby shampoo on normal sinonasal mucosal funct...

journal_title：American journal of rhinology & allergy

authors： Isaacs S,Fakhri S,Luong A,Whited C,Citardi MJ

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Nasal congestion and/or obstruction represents a prevalent and extensively studied problem. No published research exists that describes the impact of nasal hair (vibrissae) on nasal obstruction. OBJECTIVE:To assess the impact of nasal vibrissae on subjective and objective measurements of nasal obstruction. ...

journal_title：American journal of rhinology & allergy

authors： Stoddard DG,Pallanch JF,Hamilton GS

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:Nasal packing is usually performed to control bleeding after endoscopic sinus surgery (ESS). Although new packing materials have been developed, they still cause pain. This study was designed to evaluate the effect of lidocaine-soaked packs on pain after ESS. METHODS:A prospective, randomized, double-blind ...

journal_title：American journal of rhinology & allergy

authors： Mo JH,Park YM,Chung YJ

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Laryngeal edema is a life-threatening manifestation of hereditary angioedema (HAE), an autosomal-dominant disorder caused by quantitative or functional C1 esterase inhibitor (C1 INH) deficiency. The preparation of nanofiltered C1 INH (C1 INH-nf) used in this study is indicated for routine prophylaxis against...

journal_title：American journal of rhinology & allergy

authors： Riedl MA,Lumry WR,Li HH,Craig TJ,Fitts D,Kalfus I,Uknis ME

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:There is a correlation between (18)F-fluorodeoxyglucose (FDG) uptake and the level of intracellular metabolic tumor activity, which in turn may be associated with active proliferation, invasion, and prognosis as well as distant metastases in head and neck cancer. This study was designed to assess whether tum...

journal_title：American journal of rhinology & allergy

authors： Seol JH,Kim J,Lee JD,Lee JG,Yoon JH,Kim CH

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:One of the major causes of olfactory disturbances is chronic rhinosinusitis (CRS), and the main surgical modality to treat CRS is functional endoscopic sinus surgery (FESS). It, therefore, is essential to assess the effect of this surgery on olfaction. Also, it is necessary to find new ways of measuring olfa...

journal_title：American journal of rhinology & allergy

authors： Gupta D,Gulati A,Singh I,Tekur U

更新日期：2015-07-01 00:00:00

abstract：PURPOSE:Activation of adenosine monophosphate-activated protein kinase (AMPK) by metformin, as a master regulator of metabolism, is involved in airway tissue remodeling. Here, we investigated the physical role of AMPK on cell migration, matrix contraction, and the production of matrix metalloproteinases (MMP) in nasal ...

journal_title：American journal of rhinology & allergy

authors： Um JY,Lee SA,Park JH,Shin JM,Park IH,Lee HM

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Topical nasal sprays are commonly prescribed for sinonasal disease. Nasal drops applied in a head-down position are described alternatively to sprays. Multiple research methods have investigated the deposition pattern of intranasal medications, each with limitations. This pilot study analyzed the use of a co...

journal_title：American journal of rhinology & allergy

authors： Rudman KL,O'Brien EK,Leopold DA

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Fibrin glue has been a favorable hydrogel in cartilage tissue engineering, but implantation of chondrocyte-fibrin suspensions have resulted in volume loss. In this study, human septal cartilage chips were seeded onto a fibrin scaffold, and cellular proliferation and production of cartilaginous extracellular ...

journal_title：American journal of rhinology & allergy

authors： Sage A,Chang AA,Schumacher BL,Sah RL,Watson D

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Specific antibody deficiency may predispose patients to recurrent respiratory tract infections. There is limited literature assessing specific antibody deficiency in chronic rhinosinusitis (CRS). This study evaluated the role of specific antibody deficiency in patients with CRS who have failed medical therap...

journal_title：American journal of rhinology & allergy

authors： Carr TF,Koterba AP,Chandra R,Grammer LC,Conley DB,Harris KE,Kern R,Schleimer RP,Peters AT

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:The management of allergic rhinitis (AR) encompasses education, pharmacotherapy, immunotherapy, and surgery. FK506 (tacrolimus) is an immunosuppressant that inhibits allergic reactions. The purpose of this study was to reveal whether FK506 treatment reduces allergic inflammation in an AR mouse model and to ...

journal_title：American journal of rhinology & allergy

authors： Shin JH,Park HR,Kim SW,Park CS,Cho JH,Park YJ,Kim SW

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Computed tomography (CT) of the paranasal sinuses is the diagnostic reference standard for chronic rhinosinusitis and related inflammatory sinus pathology. Nasal nitric oxide (nNO) levels have been investigated as a diagnostic tool in sinus disease because it decreases with sinus obstruction. OBJECTIVE:The ...

journal_title：American journal of rhinology & allergy

authors： Oliver JD,Lim KG,O'Brien EK

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:B-cell responses may play a role in the pathogenesis of nasal polyposis via local IgA and IgE production and activation of eosinophils and mast cells. B-cell attracting chemokines may therefore have relevance in the pathogenesis of chronic rhinosinusitis with nasal polyps (CRSwNPs) Methods: Polyp and inferio...

journal_title：American journal of rhinology & allergy

authors： Patadia M,Dixon J,Conley D,Chandra R,Peters A,Suh LA,Kato A,Carter R,Harris K,Grammer L,Kern R,Schleimer R

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:A remarkable relationship between upper airway conditions and lung diseases has been reported. At the same time, sinonasal findings in chronic cough patients have not been fully examined. OBJECTIVE:The purpose of this study is to show paranasal sinus findings and lung function in chronic cough patients with...

journal_title：American journal of rhinology & allergy

authors： Kariya S,Okano M,Higaki T,Tachibana T,Rikimaru T,Nishizaki K

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:MUC5AC, a major secreted mucin, is increased in chronic inflammatory airway disease. Spleen tyrosine kinase (SYK) is a mediator, which acts as an important regulator of intracellular signal transduction in the inflammatory response. SYK was originally identified in hematopoietic cells, and its expression in ...

journal_title：American journal of rhinology & allergy

authors： Na HG,Bae CH,Choi YS,Song SY,Kim YD

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVES:Inadvertent intracranial injury from nasogastric tube (NGT) placement is a described and potentially fatal complication following endoscopic transsphenoidal hypophysectomy (TSH). This cadaver study assessed the role of middle turbinate (MT) preservation and medialization in preventing accidental skull base i...

journal_title：American journal of rhinology & allergy

authors： Shah J,Tang D,Grafmiller K,Cappello ZJ,Roxbury C,Sindwani R

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Platelet-activating factor (PAF) is a lipid mediator produced by most inflammatory cells. Clinical and experimental findings suggest that PAF participates in allergic rhinitis (AR) pathogenesis. The aim was to assess the PAF ability to induce clinical response in nasal airway after local stimulation. METHOD...

journal_title：American journal of rhinology & allergy

authors： Muñoz-Cano R,Valero A,Roca-Ferrer J,Bartra J,Sanchez-Lopez J,Mullol J,Picado C

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Aspirin-exacerbated respiratory disease (AERD) affects 7% of asthmatics. Usual therapies are inadequate for asthma and/or nasal polyposis, leading to decreased quality of life. OBJECTIVE:Our objective was to evaluate the efficacy of dupilumab in AERD patients with uncontrolled, chronic rhinosinusitis with n...

journal_title：American journal of rhinology & allergy

authors： Mustafa SS,Vadamalai K,Scott B,Ramsey A

更新日期：2020-09-23 00:00:00

abstract：BACKGROUND:The association between olfactory dysfunction (OD) and cognitive decline is becoming apparent in the emerging literature. However, the literature demonstrating a similar effect between gustatory dysfunction (GD) and cognition is not well established. OBJECTIVE:To determine whether OD and GD are independentl...

journal_title：American journal of rhinology & allergy

authors： Churnin I,Qazi J,Fermin CR,Wilson JH,Payne SC,Mattos JL

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:This study was designed to determine if the addition of large-volume, low-positive pressure nasal irrigations delivered with isotonic sodium chloride (hereinafter "saline") added to intranasal corticosteroid therapy improves quality of life and objective measures of nasal breathing in patients with allergic ...

journal_title：American journal of rhinology & allergy

authors： Nguyen SA,Psaltis AJ,Schlosser RJ

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:The prevalence of rhinitis has been reported to be higher in urban areas. OBJECTIVE:To determine the prevalence of rhinitis in schoolchildren who lived on two islands in the Brazilian Amazon, including a rural island and an urban island, and to identify the associated risk factors. METHODS:Four hundred chi...

journal_title：American journal of rhinology & allergy

authors： Freitas MS,de Córdoba Lanza F,Monteiro JC,Solé D

更新日期：2016-05-01 00:00:00

abstract：INTRODUCTION:Accountable care organizations (ACO) and alternative payment models are a sign of the change in reimbursement from fee-for-service to value-based reimbursement. The focus of health care under ACOs is represented by the Triple Aim: to improve the experience of health care, improve the health of populations,...

journal_title：American journal of rhinology & allergy

authors： Barry JY,McCrary HC,Kent S,Saleh AA,Chang EH,Chiu AG

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Post-viral olfactory dysfunction is a common cause of both short- and long-term smell alteration. The coronavirus pandemic further highlights the importance of post-viral olfactory dysfunction. Currently, a comprehensive review of the neural mechanism underpinning post-viral olfactory dysfunction is lacking....

journal_title：American journal of rhinology & allergy

authors： Lee JC,Nallani R,Cass L,Bhalla V,Chiu AG,Villwock JA

更新日期：2020-09-11 00:00:00

abstract：BACKGROUND:Nasal obstruction (NO) is a very common symptom, but its effect on nasal physiology has not been fully understood. We performed this study to determine the effect of severity of NO due to inferior turbinate hypertrophy on airflow pattern using the computational fluid dynamics simulations. METHODS:A three-di...

journal_title：American journal of rhinology & allergy

authors： Lee HP,Poh HJ,Chong FH,Wang de Y

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Patients report that nasal congestion is the most bothersome symptom of allergic rhinitis (AR). Recently, a short, patient-reported congestion screener questionnaire, the Congestion Quantifier Seven-Item Test (CQ7), was developed to identify a level of congestion that may warrant patients seeking evaluation ...

journal_title：American journal of rhinology & allergy

authors： Stull DE,Meltzer EO,Krouse JH,Roberts L,Kim S,Frank L,Naclerio R,Lund V,Long A

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Nasal polyposis represents the end point of multiple inflammatory pathways and controversy continues as to the exact roles of medical and surgical approaches in the management of nasal polyposis. METHODS:A combination of both is often required to manage polyps adequately with surgery and intranasal steroids...

journal_title：American journal of rhinology & allergy

authors： Aouad RK,Chiu AG

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:The impact of middle turbinate resection (MTR) on olfaction remains a point of debate in the current literature. Few studies have objectively evaluated olfactory cleft airflow following MTR; thus, the mechanism by which MTR may impact olfaction is poorly understood. It is not known whether the postsurgical c...

journal_title：American journal of rhinology & allergy

authors： Alam S,Li C,Bradburn KH,Zhao K,Lee TS

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Oxidative stress may play a role in the pathophysiology of several diseases including allergic rhinitis (AR). In children with AR an antioxidant enzyme paraoxonase (PON1) has not been previously investigated. The aim of this study was to investigate plasma PON1 activity and plasma total oxidant status (TOS)...

journal_title：American journal of rhinology & allergy

authors： Ozkaya E,Akduman H,Erenberk U,Demir A,Dundaroz MR

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:This study evaluates if there is any benefit of adding epinephrine to lidocaine in patients undergoing diagnostic rigid nasal endoscopy. A prospective, randomized, double-blinded study was performed. METHODS:Seventy patients were randomized to receive either 2% lidocaine or 2% lidocaine with 0.2% epinephrin...

journal_title：American journal of rhinology & allergy

authors： Al-Qudah M

更新日期：2014-11-01 00:00:00