[Good survival of Icelandic men diagnosed with testicular seminoma between 1971 and 1990 - A retrospective study.].

Abstract:

:Testicular cancer is the most common cancer diagnosed in males aged 20 to 34 in Iceland. A retrospective population-based study was carried out on all Icelandic males diagnosed between 1971 and 1990 to evaluate presentation and survival of seminoma in Iceland. Fortyseven males with average age of 36 years (range 21-71) were included. Clinical informations were gained from the Icelandic Cancer Registry and hospital records. The staging system used was a modification of the system orginally proposed by Boden and Gibb and crude probability of survival was evaluated with the Kaplan-Meier method. Age standardized incidence for seminoma was 2.0/ 100,000 males per year for the whole period. Forty-five patients were diagnosed with symptoms where testicular swelling (98%) and pain (42%) were the most common symptoms. Two patients were diagnosed incidentally. All the patients except one underwent orchiectomy, 66% also received radiotherapy and 9% chemotherapy. Average tumor diameter was 8 cm before 1981 but 5.2 cm after 1981 (p=0.02). Most patients were diagnosed in stage I (73%), but 27% had disseminated disease at diagnosis (stage II-IV), most commonly retroperitoneal lymphnode metastases (85%). Crude five and 10 year survival was 89% and 84% respectively. Nine patients have died (August 1994) but none of seminoma. The incidence of seminoma is moderate in Iceland compared to the Nordic countries. Clinical symptoms and stage at diagnosis are similar. Survival is excellent for the group as a whole. For small localized tumors orchiectomy and surveillance seem to be an appropriate approach.

journal_name

Laeknabladid

journal_title

Laeknabladid

authors

Gudbjartsson T,Bjornsson R,Magnusson K,Bjornsson S,Einarsson GV

subject

Has Abstract

pub_date

1996-03-01 00:00:00

pages

202-10

issue

3

eissn

0023-7213

issn

1670-4959

journal_volume

82

pub_type

杂志文章
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  • [The prevalence of sicca symptoms in Iceland.].

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    authors: Atladóttir J,Guðmundsson OG,Holbrook P,Sigurðsson R,Gudbjornsson B

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  • [Extremely Low Birthweight Infants in Iceland. Neurodevelopmental profile at five years of age.].

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    authors: Georgsdóttir I,Sæmundsen E,Leósdóttir T,Símonardóttir I,Egilson ST,Dagbjartsson A

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  • [Lung Transplantation in Icelanders].

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    journal_title:Laeknabladid

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    doi:10.17992/lbl.2016.05.80

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  • [Risk assessment for fetal aneuploidy after nuchal translucency measurement.].

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    authors: Haraldsdóttir KR

    更新日期:2001-05-01 00:00:00

  • [Multiple sclerosis and childbirth: Relapse frequency and pregnancy outcome. A hospital-based retrospective study].

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    doi:10.17992/lbl.2020.12.612

    authors: Bergthorsdóttir BB,Thorhallsdottir RL,Steingrimsdottir T,Hjaltason H

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  • [Diagnosis and treatment of hair pulling- and skin picking disorder].

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    更新日期:2012-03-01 00:00:00

  • [The prevalence of fibromyalgia and chronic widespread musculoskeletal pain in Iceland.].

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    authors: Birgisson H,Jonsson H,Geirsson AJ

    更新日期:1998-09-01 00:00:00

  • [Survival and causes of death in children diagnosed with cancer in Iceland 1981-2006].

    abstract:OBJECTIVE:Of children diagnosed with cancer, approximately one fourth die of the disease or disease related complications. The aim of this study was to investigate survival and causes of death in children with cancer in Iceland. METHODS:This study is retrospective; population based and includes all children, less than...

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  • [Hepatitis A in Iceland].

    abstract:INTRODUCTION:Hepatitis A virus (HAV) epidemics occurred repeatedly in Iceland in the early 20th century, but since then few cases have been reported and no epidemics since 1952. The latest Icelandic studies on HAV from around 1990 showed low incidence of infection and de-- creasing prevalence of antibodies. The objecti...

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  • [Acute myocardial infarction in Iceland 1982-1983. Prognosis and risk factors in the pre-thrombolytic era.].

    abstract::This nationwide study describes the short- and longterm outcome of acute myocardial infarction in Iceland 1982-83 prior to the routine use of aspirin and thrombolytic therapy. The material consists of 486 cases of acute myocardial infarction, 390 men and 96 women aged 25-64 years. Death prior to hospitalization occure...

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    pub_type: 杂志文章

    doi:

    authors: Agnarsson U,Sigfusson N,Gudmundsdottir II,Stefansdottir I

    更新日期:1996-04-01 00:00:00

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    abstract::Pulmonary arterial hypertension is a rare disease with substantial morbidity and mortality. In the last few years significant progress has been made in the understanding of the pathogenesis and course of the disease. New classification and drug treatment have emerged. The new drugs are expensive but can improve qualit...

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    authors: Kristinsson VH,Kristinsson JR,Jónmundsson GK,Jónsson OG,Thornórsson AV,Haraldsson A

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  • [Extremely Low Birthweight Infants in Iceland. Health and development.].

    abstract:OBJECTIVE:Survival of extremely low birthweight infants (BW<1000g) in Iceland has increased in recent years, especially since the availability of surfactant therapy for Respiratory Distress Syndrome of Prematurity. This study was part of a geographically defined national study on survival, health, development and longt...

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  • [Aortic valve replacement for aortic stenosis in Iceland 2002-2006: Indications and short term complications].

    abstract:OBJECTIVE:Information on surgical outcome of aortic valve replacement (AVR) has not been available in Iceland. We therefore studied the indications, short-term complications and operative mortality in Icelandic patients that underwent AVR with aortic stenosis. MATERIAL AND METHODS:This was a retrospective study includ...

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  • [Diagnosis of osteoporosis in the elderly; an overview.].

    abstract::Measurement of bone mineral density (BMD) is the basis of the diagnosis of osteoporosis. WHO classification of osteoporosis is based on dual energy X-ray absorptiometry (DEXA) using the BMD of young women (20-30 years) as the reference value (T-score). For clinical purpose it is better to use age-matched control (Z-sc...

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  • [The imperfect equalizing device: Physician care discount cards and physician care out-of-pocket costs in Iceland.].

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  • [Treatment of hepatitis C with peginterferon and ribavirin in Iceland from 2002-2012].

    abstract:BACKGROUND/AIMS:Hepatitis C is a major cause of chronic liver disease and cirrhosis in Western countries. Its treatment aims at eradicating the virus and patients are considered cured if the virus is undetectable by PCR in blood 12-24 weeks after end of treatment (sustained virological response, SVR). The aim of this s...

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  • [Feeding patterns and risk factors in an epidemic of neonatal necrotizing enterocolitis.].

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    journal_title:Laeknabladid

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    doi:

    authors: Hreinsdottir KT,Dagbjartsson A,Johannsson JH

    更新日期:1998-03-01 00:00:00

  • [Radiofrequency catheter ablations of supraventricular tachycardias in Iceland.].

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  • [Viral hepatitis B and C among immigrants in Iceland].

    abstract:BACKGROUND:Viral hepatitis B and C are a major health problem worldwide. The prevalence of these diseases varies throughout the world. In Iceland, the incidence of hepatitis B and C has increased in recent years. At the same time, the number of immigrants from countries where viral hepatitis is endemic, has also increa...

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  • [Breakthrough in research on pluripotent stem cells and their application in medicine].

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