Blocking interleukin-1 in rheumatic diseases.

abstract：:Dipeptidyl peptidase IV (DPPIV) is a multifunctional cell surface aminopeptidase with ubiquitous expression and it has a variety of functional properties in the development of human malignancies. In the present study, we showed the possible correlation between DPPIV/CD26 expression and less migratory potential with de...

journal_title：Annals of the New York Academy of Sciences

authors： Kajiyama H,Shibata K,Terauchi M,Ino K,Nawa A,Kikkawa F

更新日期：2006-11-01 00:00:00

abstract：:The entry of resting T cells into the G1 phase of the cell cycle after stimulation by mitogens is controlled by a series of biochemical events that are independent of growth factors. These events follow the initial signals stimulated through the engagement of the T-cell receptor and include activation of the cyclin-de...

journal_title：Annals of the New York Academy of Sciences

authors： Modiano JF,Domenico J,Szepesi A,Terada N,Lucas JJ,Gelfand EW

更新日期：1995-09-07 00:00:00

abstract：:The song system of oscine birds has become a versatile model system that is used to study diverse problems in neurobiology. Because the song system is often studied with the intention of applying the results to mammalian systems, it is important to place song system brain nuclei in a broader context and to understand ...

journal_title：Annals of the New York Academy of Sciences

authors： Farries MA

更新日期：2004-06-01 00:00:00

abstract：:Patients with renal impairment have an increased risk for cardiovascular disease, which may be the result of advanced glycation end products (AGEs). The aim of this study was to investigate the levels of AGE peptides in relation to kidney function and to study the relationship of AGE peptides with endothelial function...

journal_title：Annals of the New York Academy of Sciences

authors： Schalkwijk CG,Ter Wee PM,Stehouwer CD

更新日期：2005-06-01 00:00:00

abstract：:Birds, the most species-rich monophyletic group of land vertebrates, have been subject to some of the most intense sequencing efforts to date, making them an ideal case study for recent developments in genomics research. Here, we review how our understanding of bird genomes has changed with the recent sequencing of mo...

journal_title：Annals of the New York Academy of Sciences

authors： Kapusta A,Suh A

更新日期：2017-02-01 00:00:00

abstract：:Iddm4 is a dominant non-major histocompatibility complex (MHC) determinant of diabetes susceptibility in BBDR rats treated with poly I:C, plus depletion of regulatory T cells. In congenic MHC-identical normal WF rats, Iddm4(d) sensitively and specifically predicts induced diabetes. We report a new diabetes-susceptible...

journal_title：Annals of the New York Academy of Sciences

authors： Blankenhorn EP,Descipio C,Rodemich L,Cort L,Leif JH,Greiner DL,Mordes JP

更新日期：2007-04-01 00:00:00

abstract：:Acute phase proteins (APPs) are a group of serum proteins that undergo dramatic changes in concentration during times of inflammation. Many APPs are heavily glycosylated, and their sugar content and complexity change in the presence of cancer-induced chronic inflammation. These changes in glycosylation are currently b...

journal_title：Annals of the New York Academy of Sciences

authors： Dempsey E,Rudd PM

更新日期：2012-04-01 00:00:00

abstract：:Aberrations in estrogen signaling increase breast cancer risk. Molecular mechanisms that impact breast cancer initiation, promotion, and progression can be investigated using genetically engineered mouse models. Increasing estrogen receptor alpha (ERα) expression levels twofold is sufficient to initiate and promote br...

journal_title：Annals of the New York Academy of Sciences

authors： Furth PA,Cabrera MC,Díaz-Cruz ES,Millman S,Nakles RE

更新日期：2011-07-01 00:00:00

abstract：:Insulin-dependent diabetes mellitus (IDDM) is one of the most common chronic diseases. It is an autoimmune, polygenic disease, associated with several genes on different chromosomes. The most important gene is human leukocyte antigen (HLA), also known as major histocompatibility complex (MHC), which is located on chro...

journal_title：Annals of the New York Academy of Sciences

authors： Shtauvere-Brameus A,Ghaderi M,Rumba I,Sanjeevi CB

更新日期：2002-04-01 00:00:00

abstract：:In the study reported in this paper, we characterized PACAP in the human fetal adrenal gland and we investigated the effect of PACAP on steroid secretion from cultured fetal adrenal cells. The adrenal gland from 20-week-old fetuses contained substantial concentrations of PACAP-immunoreactive material (88.6 ng/g wet ti...

journal_title：Annals of the New York Academy of Sciences

authors： Breault L,Yon L,Montéro M,Chouinard L,Contesse V,Delarue C,Fournier A,Lehoux JG,Vaudry H,Gallo-Payet N

更新日期：2000-01-01 00:00:00

abstract：:In Wegener's granulomatosis (WG), antiproteinase 3 (PR3) autoantibodies (PR3-ANCA) are crucial in the development of generalized vasculitis. Wegener's pathognomonic lesion, a granulomatous inflammation of the upper and lower respiratory tract, contains abundant lymphocytes and macrophages. Lymphocyte clusters in germi...

journal_title：Annals of the New York Academy of Sciences

authors： Voswinkel J,Müller A,Lamprecht P

更新日期：2005-06-01 00:00:00

abstract：:Nerve agents (NAs) produce acute and long-term brain injury and dysfunction, as evident from the Japan and Syria incidents. Magnetic resonance imaging (MRI) is a versatile technique to examine such chronic anatomical, functional, and neuronal damage in the brain. The objective of this study was to investigate long-ter...

journal_title：Annals of the New York Academy of Sciences

authors： Reddy SD,Wu X,Kuruba R,Sridhar V,Reddy DS

更新日期：2020-11-01 00:00:00

abstract：:The avoidance of autoimmunity requires mechanisms to actively silence or tolerize self reactive T cells in the periphery. During infection, dendritic cells are not only capturing microbial antigens, but also are processing self antigens from dying cells as well as innocuous environmental proteins. Since the dendritic ...

journal_title：Annals of the New York Academy of Sciences

authors： Steinman RM,Hawiger D,Liu K,Bonifaz L,Bonnyay D,Mahnke K,Iyoda T,Ravetch J,Dhodapkar M,Inaba K,Nussenzweig M

更新日期：2003-04-01 00:00:00

abstract：:Membrane bioreactors can be operated with intermittent permeation and continuous aeration. Aeration close to the surface of a submerged membrane helps to maintain a membrane surface that is free from fouling. The conditions under which this occurs depend on the interaction between flux and aeration rate. Increased flu...

journal_title：Annals of the New York Academy of Sciences

authors： Howell JA,Arnot TC,Chua HC

更新日期：2003-03-01 00:00:00

abstract：:A method using laser-induced fluorescence (LIF) for in vivo cancer diagnosis of the esophagus is described. Autofluorescence of normal and malignant tissues was measured directly using a fiberoptic probe inserted through an endoscope. The measurements were performed in vivo during routine endoscopy. Measurement of the...

journal_title：Annals of the New York Academy of Sciences

authors： Vo-Dinh T,Panjehpour M,Overholt BF

更新日期：1998-02-09 00:00:00

abstract：:The contemporary world faces an unprecedented environmental challenge. Past international research has amply shown that we cannot afford to wait for a "development path" that automatically takes us on a sustainable future. Whether we look at global or local problems, the international debate increasingly points to the...

journal_title：Annals of the New York Academy of Sciences

authors： Magnani E

更新日期：2011-02-01 00:00:00

abstract：:Latent autoimmune diabetes in adults (LADA) is a special form of diabetes that is clinically similar to type 2 diabetes but with positivity for pancreatic autoantibodies. The frequency of LADA patients among all patients diagnosed as type 2 varies between 6-50% in various populations. The frequency is higher in younge...

journal_title：Annals of the New York Academy of Sciences

authors： Landin-Olsson M

更新日期：2002-04-01 00:00:00

abstract：:While the study of nationalism has received much attention throughout the social sciences and humanities, the experimental investigation of it lags behind. In this paper we review recent advances in the examination of implicit nationalism. In the first set of experiments we survey, the Palestinian, Israeli, Italian, a...

journal_title：Annals of the New York Academy of Sciences

authors： Hassin RR,Ferguson MJ,Kardosh R,Porter SC,Carter TJ,Dudareva V

更新日期：2009-06-01 00:00:00

abstract：:Astronomers and physicists of diverse interest are teaming up to study enigmatic cosmic phenomena, such as the life cycle of black holes. A "disruptive innovation" is about to emerge during the next decade: Advanced gravitational-wave observatories. The emergence of gravitational-wave physics as a viable observational...

journal_title：Annals of the New York Academy of Sciences

authors： Márka S

更新日期：2012-07-01 00:00:00

abstract：:Gypsy/Ty3 retrotransposons, a group of long terminal repeat retrotransposons related to vertebrate retroviruses, are found in the genome of many fungi, plants, and animals. Although multiple families of such retroelements are present in fish, active Gypsy/Ty3 retrotransposons have all been eliminated from the lineage ...

journal_title：Annals of the New York Academy of Sciences

authors： Volff JN

更新日期：2009-10-01 00:00:00

abstract：:The present study was aimed at finding neural correlates of aesthetic versus descriptive listening of the same musical cadences. Results showed that aesthetic listening generated greater right frontocentral negativities than did descriptive listening, indicating distinct cortical mechanisms for aesthetic versus descri...

journal_title：Annals of the New York Academy of Sciences

authors： Brattico E,Jacobsen T,De Baene W,Nakai N,Tervaniemi M

更新日期：2003-11-01 00:00:00

abstract：:Ginkgo biloba extract EGb 761 has been used for many years to treat age-related cognitive disorders including Alzheimer's disease. EGb 761 given shortly after initiating mitochondrial damage by sodium nitroprusside (nitric oxide donor) improved the mitochondrial membrane potential of PC12 cells significantly and dose ...

journal_title：Annals of the New York Academy of Sciences

authors： Eckert A,Keil U,Scherping I,Hauptmann S,Müller WE

更新日期：2005-11-01 00:00:00

abstract：:At concentrations effecting apoptosis, the alkylphosphocholine ErPC3 induced increased expression of the Rb protein in breast cancer (MCF-7) and leukemia (SKW-3, AR-230) cell lines as well as hypophosphorylation (K-562, CMLT-1, DOHH-2) and fragmentation of Rb (BV-173, SKW-3) in leukemia cell lines. ErPC3 exerts at lea...

journal_title：Annals of the New York Academy of Sciences

authors： Berger MR,Tsoneva I,Konstantinov SM,Eibl H

更新日期：2003-12-01 00:00:00

abstract：:Mouse Schwann cells and rat RN22 schwannoma cells cultured in the absence of neurons and fibroblasts produce typical basement membrane proteins. Heparan sulfate proteoglycan (low density form), nidogen, and protein BM-40 were identified by radioimmunoassays, immunoblotting, and by immunoprecipitation after metabolic l...

journal_title：Annals of the New York Academy of Sciences

authors： Dziadek M,Edgar D,Paulsson M,Timpl R,Fleischmajer R

更新日期：1986-01-01 00:00:00

abstract：:Oxyradicals are generally considered harmful byproducts of oxidative metabolism, causing molecular damage in living systems. They are implicated in various processes such as mutagenesis, aging, and series of pathological events. Although all this may be justified, evidence is accumulating that it is an oversimplified ...

journal_title：Annals of the New York Academy of Sciences

authors： Nagy IZ

更新日期：2001-04-01 00:00:00

abstract：:Scant empirical attention has been devoted to understanding endings in youth mentoring relationships, despite the frequency with which they occur. This study examined data from a mixed-methods study of mentoring relationship endings in which youth mentees, the youth's parents or guardians, mentors, and program staff w...

journal_title：Annals of the New York Academy of Sciences

authors： Spencer R,Keller TE,Perry M,Drew AL,Clark-Shim H,Horn JP,Miranda-Díaz M,McCormack MJ

更新日期：2021-01-01 00:00:00

abstract：:The effects of rhythmic auditory stimulation (RAS) on gait in adolescents with acquired brain injury (ABI) were investigated. A total of 14 adolescents with ABI were initially recruited, and 12 were included in the final analysis (n = 6 each). They were randomly assigned to the experimental (RAS) or the control (conve...

journal_title：Annals of the New York Academy of Sciences

authors： Kim SJ,Shin YK,Yoo GE,Chong HJ,Cho SR

更新日期：2016-12-01 00:00:00

abstract：:In Bar Harbor 129 dystrophic mice, thymic development is abnormal. Before weaning, the thymus is slightly smaller than in phenotypically normal littermates; after weaning, however, the lymphoid elements undergo rapid atrophy. The epithelial elements, in contrast, display hyperlasia. Thymectomy has no influence on the ...

journal_title：Annals of the New York Academy of Sciences

authors： Horrobin DF,Morgan RO,Karmali RA,Ally AI,Manku MS,Karmazyn M,Cunnane SC

更新日期：1979-01-01 00:00:00

abstract：:This study investigates the effects of agmatine on naloxone-precipitated withdrawal syndrome in morphine-dependent guinea pig ileum. Male guinea pigs that were starved for 24 hours were decapitated after cervical dislocation, and terminal portions of the ilea were removed. Segments were fixed at a resting tension of 1...

journal_title：Annals of the New York Academy of Sciences

authors： Aricioglu F,Ercil E,Dulger G

更新日期：2003-12-01 00:00:00

abstract：:Neocortex is an important part of the mammalian brain that is quite different from its homologue of the dorsal cortex in the reptilian brain. Whereas dorsal cortex is small, thin, and composed of a single layer of neurons, neocortex is thick and has six layers, while being variable across species in size, number of fu...

journal_title：Annals of the New York Academy of Sciences

authors： Kaas JH

更新日期：2011-04-01 00:00:00