Acute phase glycoproteins: bystanders or participants in carcinogenesis?

abstract：:Emerging evidence suggests that individuals who receive morphine while hospitalized demonstrate a decrease in symptoms of posttraumatic stress disorder (PTSD). However, the mechanisms of effects are not yet well understood. The goal of the current study was to examine three possible mediators for this effect. Sixty-on...

journal_title：Annals of the New York Academy of Sciences

authors： Saxe G,Geary M,Bedard K,Bosquet M,Miller A,Koenen K,Stoddard F,Moulton S

更新日期：2006-07-01 00:00:00

abstract：:Among the five enzyme complexes in the oxidative phosphorylation system, NADH-coenzyme Q oxidoreductase (also called complex I) is the largest, most intricate, and least understood. This enzyme complex spans the inner mitochondrial membrane and catalyzes the first step of electron transfer by the oxidation of NADH, an...

journal_title：Annals of the New York Academy of Sciences

authors： Lin BY,Kao MC

更新日期：2015-09-01 00:00:00

abstract：:Intravenous immunoglobulin (IVIG) and plasma exchange (PLEX) are used to treat myasthenia gravis (MG) but with little trial evidence. While a class I study provided evidence for the efficacy of IVIG treatment, the empirical support for PLEX has been less convincing until recently. In a randomized controlled single-mas...

journal_title：Annals of the New York Academy of Sciences

authors： Bril V,Barnett-Tapia C,Barth D,Katzberg HD

更新日期：2012-12-01 00:00:00

abstract：:Acylated aldose dialkyl dithioacetals with bromine undergo replacement of one alkylthio group by bromine. These unstable bromides react, as by fusion with 2,4-bis(trimethylsilyloxy)pyrimidine, to give acylated 1-(pyrimidin-1-yl) derivatives that upon saponification afford acyclic sugar nucleoside analogues, some as se...

journal_title：Annals of the New York Academy of Sciences

authors： Horton D,Baker DC,Kokrady SS

更新日期：1975-08-08 00:00:00

abstract：:In rats, arginine vasopressin augments bradycardia associated with baroreflex activation. We investigated whether modulation of peripheral cardiac parasympathetic nerve function by AVP may play a role in this effect. To accomplish this we utilized an in vivo model with which we previously demonstrated both adrenergic ...

journal_title：Annals of the New York Academy of Sciences

authors： Pardini BJ,Lund DD,Schmid PG

更新日期：1993-07-22 00:00:00

abstract：:Peripheral administration of lipopolysaccharide (LPS) in an amount that produces acute stress has been found to affect the catecholamine systems in the brain. Acute peripheral LPS administration activated norepinephrine (NE) metabolism in the locus ceruleus (LC). Approximately 40% of murine LC neurons project to the o...

journal_title：Annals of the New York Academy of Sciences

authors： Ota A,Mori K,Kaneko YS,Nakashima A,Nagatsu I,Nagatsu T

更新日期：2008-12-01 00:00:00

abstract：:It is thought that human natural killer (NK) lymphocytes should not damage self-tissues due to the inhibiting signal initiated by the engagement of one or another inhibitory receptor superfamily (IRS) members with self-human histocompatibility antigen (HLA)-I. During viral infection, the low expression of self-HLA-I o...

journal_title：Annals of the New York Academy of Sciences

authors： Poggi A,Prevosto C,Zancolli M,Canevali P,Musso A,Zocchi MR

更新日期：2007-08-01 00:00:00

abstract：:We review here evidence that a large portion of the caudomedial telencephalon of songbirds, distinct from the song control circuit, is involved in the perceptual processing of birdsong. When songbirds hear song, a number of caudomedial pallial areas are activated, as revealed by expression of the activity-dependent ge...

journal_title：Annals of the New York Academy of Sciences

authors： Mello CV,Velho TA,Pinaud R

更新日期：2004-06-01 00:00:00

abstract：:At concentrations effecting apoptosis, the alkylphosphocholine ErPC3 induced increased expression of the Rb protein in breast cancer (MCF-7) and leukemia (SKW-3, AR-230) cell lines as well as hypophosphorylation (K-562, CMLT-1, DOHH-2) and fragmentation of Rb (BV-173, SKW-3) in leukemia cell lines. ErPC3 exerts at lea...

journal_title：Annals of the New York Academy of Sciences

authors： Berger MR,Tsoneva I,Konstantinov SM,Eibl H

更新日期：2003-12-01 00:00:00

abstract：:Pregnant female Sprague-Dawley rats were injected with either 40 mg/kg (-)cocaine hydrochloride or an equivalent volume of 0.9% saline, subcutaneously (s.c.), once daily from gestational day 12 (GD 12) to GD 21. Gestational cocaine exposure had no effect on maternal weight gain, length of gestation, birthweight, fetal...

journal_title：Annals of the New York Academy of Sciences

authors： Choi SJ,Mazzio E,Soliman KF

更新日期：1998-05-30 00:00:00

abstract：:Scant empirical attention has been devoted to understanding endings in youth mentoring relationships, despite the frequency with which they occur. This study examined data from a mixed-methods study of mentoring relationship endings in which youth mentees, the youth's parents or guardians, mentors, and program staff w...

journal_title：Annals of the New York Academy of Sciences

authors： Spencer R,Keller TE,Perry M,Drew AL,Clark-Shim H,Horn JP,Miranda-Díaz M,McCormack MJ

更新日期：2021-01-01 00:00:00

abstract：:Catecholamines (CAs) are significantly involved in the regulation of homeostasis of the organism at rest and especially during stressful situations. Stress induces increases in plasma CA (epinephrine and norepinephrine) levels and prolactin (PRL) release from the adenopituitary. We have recently observed that salsolin...

journal_title：Annals of the New York Academy of Sciences

authors： Bodnar I,Mravec B,Kubovcakova L,Fekete MI,Nagy GM,Kvetnansky R

更新日期：2004-06-01 00:00:00

abstract：:Tight junction (TJ) properties are determined by membrane protein complexes of neighboring cells that form both a barrier and a selective pathway for paracellular substrate transport. Our previous work supports the view that paracellular permeability changes in the thick ascending limb (TAL) may underlie the mechanism...

journal_title：Annals of the New York Academy of Sciences

authors： Shan Q,Himmerkus N,Hou J,Goodenough DA,Bleich M

更新日期：2009-05-01 00:00:00

abstract：:Achalasia is a primary motility disorder of the esophagus, and while there are several treatment options, there is no consensus regarding them. When therapeutic intervention for achalasia fails, a careful evaluation of the cause of the persistent or recurrent symptoms using upper endoscopy, esophageal manometry, and c...

journal_title：Annals of the New York Academy of Sciences

authors： Felix VN,Murayama KM,Bonavina L,Park MI

更新日期：2020-12-01 00:00:00

abstract：:In this review, we present (1) the scientific basis for the use of high-dose immunosuppression followed by autologous peripheral blood hematopoietic stem cell transplantation for newly diagnosed type 1 diabetes (T1D); (2) an update of the clinical and laboratory outcome of 20 patients transplanted at the University Ho...

journal_title：Annals of the New York Academy of Sciences

authors： Voltarelli JC,Couri CE,Stracieri AB,Oliveira MC,Moraes DA,Pieroni F,Barros GM,Madeira MI,Malmegrim KC,Foss-Freitas MC,Simões BP,Foss MC,Squiers E,Burt RK

更新日期：2008-12-01 00:00:00

abstract：:Analysis of fetal DNA in maternal plasma has recently been introduced as a new method for noninvasive prenatal diagnosis. In the majority of cases, the Y chromosome-specific sequences are commonly used as a fetus-specific marker with a high risk of false-negative cases. We attempted to develop a sensitive and reliable...

journal_title：Annals of the New York Academy of Sciences

authors： Vecchione G,Tomaiuolo M,Sarno M,Colaizzo D,Petraroli R,Matteo M,Greco P,Grandone E,Margaglione M

更新日期：2008-08-01 00:00:00

abstract：:Systemic lupus erythematosus (SLE) is an idiopathic autoimmune disease characterized by impaired T lymphocyte immune effector functions. We have identified a disorder of signal transduction in SLE T cells involving the cyclic AMP/protein kinase A (cAMP/PKA) pathway. Cyclic AMP-stimulated PKA-catalyzed protein phosphor...

journal_title：Annals of the New York Academy of Sciences

authors： Kammer GM

更新日期：2002-06-01 00:00:00

abstract：:A radioimmunoassay method (RIA) with specific antisera for human and rat alpha fetoprotein (AFP) was used to study the evolution of AFP levels in humans and rats, respectively, throughout the life span. Sera of 66 rats, aged 3-70 weeks, as well as sera of 201 clinically well children, 192 healthy blood donors, and 16...

journal_title：Annals of the New York Academy of Sciences

authors： Masseyeff R,Gilli J,Krebs B,Calluaud A,Bonet C

更新日期：1975-08-22 00:00:00

abstract：:More effective therapies have improved survival times of HIV+ patients, resulting in a higher prevalence of long-term complications of the disease. This review focuses on HIV-associated cardiovascular pathology, correlating the morphologic findings to clinical syndromes of HIV disease/AIDS. ...

journal_title：Annals of the New York Academy of Sciences

authors： d'Amati G,di Gioia CR,Gallo P

更新日期：2001-11-01 00:00:00

abstract：:The discovery of AQP4-IgG (a pathogenic antibody that targets the astrocytic water channel aquaporin-4), as the first sensitive and specific biomarker for any inflammatory central nervous system demyelinating disease (IDD), has shifted emphasis from the oligodendrocyte and myelin to the astrocyte as a central immunopa...

journal_title：Annals of the New York Academy of Sciences

authors： Pittock SJ,Lucchinetti CF

更新日期：2016-02-01 00:00:00

abstract：:Thymic tolerance depends on induction of apoptosis (programmed cell death) in immature thymocytes by antigen/MHC complexes on dendritic cells (and possibly other bone marrow-derived APCs). Interactions with antigen/MHC complexes on thymic epithelial cells promote maturation of double-positive thymocytes to single-posi...

journal_title：Annals of the New York Academy of Sciences

authors： Owen JJ,Jenkinson EJ

更新日期：1992-11-21 00:00:00

abstract：:We have described a family of adrenocortical tumor cell mutants (including clones OS3, Y6, and 10r9) that are resistant to ACTH because they fail to express the gene encoding the ACTH receptor (MC2R). The MC2R deficiency results from a mutation that impairs the activity of the nuclear receptor steroidogenic factor 1 (...

journal_title：Annals of the New York Academy of Sciences

authors： Schimmer BP,Cordova M,Tsao J,Frigeri C

更新日期：2003-06-01 00:00:00

abstract：:Image processing in fluid mechanics has become an important quantitative tool for flow analysis. The feasibility of simultaneous measurements of instantaneous velocity and temperature fields, as well as for tracking interfaces, creates a functional tool to describe thermally driven flows accompanied by phase change. T...

journal_title：Annals of the New York Academy of Sciences

authors： Kowalewski TA

更新日期：2002-10-01 00:00:00

abstract：:The induction of ornithine decarboxylase (ODC) during G1 phase of the cell cycle appears to be universal and essential for cell cycle progression. This induction has been demonstrated in at least 23 cell types in response to various growth stimuli. Further, specific inhibitors of ODC added to several of these cell lin...

journal_title：Annals of the New York Academy of Sciences

authors： Russell DH,Haddox MK

更新日期：1981-02-27 00:00:00

abstract：:Long-lived proteins undergo age-related postsynthetic modifications by glycation and advanced glycation end products (AGEs), which destabilize them by altering their conformation and charge. It was accidentally discovered that ornithine (orn) increased with age in acid hydrolyzates of human skin collagen and lens crys...

journal_title：Annals of the New York Academy of Sciences

authors： Sell DR,Monnier VM

更新日期：2005-06-01 00:00:00

abstract：:Parkinson's disease is a neurodegenerative process characterized by progressive degeneration of the substantia nigra and concurrent loss of neuromelanin in these structures. The present hypothesis suggests that progression of Parkinson's disease may be reduced by enhancing the regional levels of neuroprotective factor...

journal_title：Annals of the New York Academy of Sciences

authors： Halabe Bucay A

更新日期：2008-11-01 00:00:00

abstract：:1. The flow divider of the brachiocephalic branching of the rabbit aorta had both high and low shear stress regions, each of which was covered by endothelial cells with low and high permeability respectively, even in normolipidemic intact rabbits. When rabbits were placed on an atherogenic diet, low shear regions were...

journal_title：Annals of the New York Academy of Sciences

authors： Yoshida Y,Okano M,Wang S,Kobayashi M,Kawasumi M,Hagiwara H,Mitsumata M

更新日期：1995-01-17 00:00:00

abstract：:While there has been substantial growth in early childhood development (ECD) services in low- and middle-income countries (LMICs), there is considerable inequity in their distribution and quality. Evidence-based governance strategies are necessary, but currently they are insufficient for widespread, quality implementa...

journal_title：Annals of the New York Academy of Sciences

authors： Britto PR,Yoshikawa H,van Ravens J,Ponguta LA,Reyes M,Oh S,Dimaya R,Nieto AM,Seder R

更新日期：2014-01-01 00:00:00

abstract：:Aged F344 female rats (21 months) showed decreased performance, as compared to young rats (4 months), on an object recognition memory task. Golgi impregnation measured dendritic spine density of pyramidal neurons in the prefrontal cortex (layer II-III), a brain area important for recognition memory. Densities of spine...

journal_title：Annals of the New York Academy of Sciences

authors： Wallace M,Frankfurt M,Arellanos A,Inagaki T,Luine V

更新日期：2007-02-01 00:00:00

abstract：:The search for tumor markers suitable for use in diagnosis and management of patients with lung cancer has met with limited success because each available marker lacks sufficient sensitivity and specificity. We have begun a collaborative study to evaluate multiple simultaneous serum markers to determine whether there ...

journal_title：Annals of the New York Academy of Sciences

authors： McIntire KR,Radovich BT,Gail MH,Go VL

更新日期：1983-01-01 00:00:00