Military combat and burden of subclinical atherosclerosis in middle aged men: the ARIC study.

Abstract:

BACKGROUND:Studies of the cardiovascular consequences of combat stress are few and inconclusive. OBJECTIVE:The association between combat exposure and subclinical atherosclerosis at Atherosclerosis Risk in Communities (ARIC) Study visits 1 (1987-1989) and 2 (1990-1992) was assessed among 5347 men from four U.S. communities. METHODS:Measured an average of 36 years after military entry, carotid intima-media thickness (CIMT) and carotid plaque among non-combat veterans (n=2127) were compared with non-veterans (n=2042) and veterans reporting combat experience (n=1178). RESULTS:Compared to non-combat veterans, non-veterans (risk difference (RD): 10.61; 95% confidence interval (CI): 0.81, 20.41) and combat veterans (RD: 12.79; 95% CI: 0.72, 24.86) had higher age-adjusted mean CIMT. Differences remained for combat veterans after adjustment for race, father's education and age at service entry but not years of service and for non-veterans after adjustment for race but not father's education. No differences in carotid plaque were noted. CONCLUSION:Results do not suggest that combat has a long-term detrimental effect on subclinical atherosclerosis among men.

journal_name

Prev Med

journal_title

Preventive medicine

authors

Johnson AM,Rose KM,Elder GH Jr,Chambless LE,Kaufman JS,Heiss G

doi

10.1016/j.ypmed.2010.02.009

subject

Has Abstract

pub_date

2010-05-01 00:00:00

pages

277-81

issue

5-6

eissn

0091-7435

issn

1096-0260

pii

S0091-7435(10)00064-2

journal_volume

50

pub_type

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