Gene expression profiles of recurrent acute pancreatitis risk in patients with sustained chylomicronemia.

abstract：:In cases of thyroid papillary carcinoma, a less aggressive cancer, surgeons may hesitate to perform total thyroidectomy on patients with poor general condition because these may experience longer survival without undergoing surgery. To investigate the influence of general patient condition on the patients' survival wh...

journal_title：Endocrine journal

authors： Shinohara S,Kikuchi M,Harada H,Takebayashi S,Yunoki K,Yamazaki K

更新日期：2016-11-30 00:00:00

abstract：:Recent studies have demonstrated that troglitazone has the capacity to improve insulin resistance. The present study was undertaken to determine the effect of troglitazone on in vivo insulin action, the activities of the pyruvate dehydrogenase (PDH) complex and 3-hydroxyacyl-CoA dehydrogenase (3-HADH) in muscle, and m...

journal_title：Endocrine journal

authors： Oshida Y,Kako M,Nakai N,Shimomura Y,Li L,Sato J,Ohsawa I,Sato Y

更新日期：1999-10-01 00:00:00

abstract：:It has been demonstrated the involvement of branched-chain amino acids (BCAA) on obesity and related metabolic disorder. We investigated the effects of branched-chain amino acids (BCAA) on obesity and on glucose/fat homeostasis in mice fed on a high-fat (45%) diet. BCAA was dissolved in 0.5% methylcellulose and added ...

journal_title：Endocrine journal

authors： Arakawa M,Masaki T,Nishimura J,Seike M,Yoshimatsu H

更新日期：2011-01-01 00:00:00

abstract：:Endothelial dysfunction is considered to be an early event in the development of atherosclerosis. The present study was undertaken to evaluate endothelial function and biochemical markers in type 2 diabetes mellitus (T2DM) patients before and after treatment with or without pioglitazone (PIO). Forty-one T2DM patients ...

journal_title：Endocrine journal

authors： Tsuchiya K,Akaza I,Yoshimoto T,Hirata Y

更新日期：2009-01-01 00:00:00

abstract：:In hope of understanding possible roles of estrogen during early embryogenesis, we examined the expression of both estrogen receptor alpha (ER alpha) and ER beta, a recently cloned novel subtype, in mouse oocytes and preimplantation embryos by means of reverse transcription polymerase chain reaction (RT-PCR). To inves...

journal_title：Endocrine journal

authors： Hiroi H,Momoeda M,Inoue S,Tsuchiya F,Matsumi H,Tsutsumi O,Muramatsu M,Taketani Y

更新日期：1999-02-01 00:00:00

abstract：:Aim of this study was to examine the association between the severity of obstructive sleep apnea (OSA) and dysglycemia in Japanese individuals with and without type 2 diabetes (T2DM). We enrolled 115 individuals diagnosed with OSA with an apnea hypopnea-index (AHI) ≥ 20 in whom continuous positive airway pressure (CPA...

journal_title：Endocrine journal

authors： Kurosawa H,Saisho Y,Fukunaga K,Haraguchi M,Yamasawa W,Kurihara I,Betsuyaku T,Itoh H

更新日期：2018-01-30 00:00:00

abstract：:The antidiabetic effects of Lactobacillus casei (LC) on a non-insulin-dependent diabetes mellitus (NIDDM) model, KK-Ay mice, were investigated. The oral administration of LC to male 4-week-old KK-Ay mice, or raising the mice on a 0.05% LC-containing diet significantly decreased the plasma glucose at 8 to 10 weeks of a...

journal_title：Endocrine journal

authors： Matsuzaki T,Yamazaki R,Hashimoto S,Yokokura T

更新日期：1997-06-01 00:00:00

abstract：:TSH receptor antibody (TRAb) titer has been reported to be correlated with Graves' ophthalmopathy (GO). However, the correlation between GO activity and TRAb titer assessed with a third-generation assay has not been reported. We enrolled 238 untreated Graves' disease patients who came to the outpatient clinic of Ito H...

journal_title：Endocrine journal

authors： Mukasa K,Yoshimura Noh J,Kouzaki A,Ohye H,Kunii Y,Watanabe N,Yoshihara A,Matsumoto M,Suzuki M,Ito K

更新日期：2016-01-01 00:00:00

abstract：:We compared treatment satisfaction between daily dipeptidyl peptidase-4 (DPP-4) inhibitors and a weekly DPP-4 inhibitor in patients with type 2 diabetes. The study was a 12-week, open-label, randomized, multicenter, controlled trial. Participants were Japanese patients with type 2 diabetes who had received daily DPP-4...

journal_title：Endocrine journal

authors： Oita M,Miyoshi H,Ono K,Nakamura A,Cho KY,Nomoto H,Yamamoto K,Omori K,Manda N,Kurihara Y,Aoki S,Atsumi T

更新日期：2018-02-26 00:00:00

abstract：:Recent studies indicate that succinate dehydrogenase (SDH) genes B, C, or D are, at least partly, involved in the pathogenesis of pheochromocytoma or paraganglioma. Of these three genes, the SDHD gene mutation is most closely related with paragangliomas of the neck. Here we describe a case of an SDHD-related paragangl...

journal_title：Endocrine journal

authors： Yamashita R,Usui T,Hashimoto S,Suzuki H,Takahashi M,Honkura K,Iwamoto K,Kodama E,Tagami T,Naruse M,Shimatsu A,Kaise K

更新日期：2009-01-01 00:00:00

abstract：:We provide the details of the successful management of a patient with active Cushing's disease complicated with coronavirus disease 2019 (COVID-19) pneumonia. The patient was a 27-year-old Japanese female healthcare worker who was scheduled to undergo pituitary surgery for Cushing's disease. She had been in close cont...

journal_title：Endocrine journal

authors： Yuno A,Kenmotsu Y,Takahashi Y,Nomoto H,Kameda H,Cho KY,Nakamura A,Yamashita Y,Nakamura J,Nakakubo S,Kamada K,Suzuki M,Sugino H,Inoshita N,Konno S,Miyoshi H,Atsumi T,Sawamura Y,Shimatsu A

更新日期：2020-12-24 00:00:00

abstract：:This study aimed to assess the relationship between the metabolic effect after laparoscopic sleeve gastrectomy (LSG) in morbidly obese Japanese patients, with or without type 2 diabetes mellitus (T2DM), and improved pancreatic steatosis (PS). The study enrolled 27 morbidly obese Japanese patients who were undergoing L...

journal_title：Endocrine journal

authors： Umemura A,Sasaki A,Nitta H,Baba S,Ando T,Kajiwara T,Ishigaki Y

更新日期：2017-05-30 00:00:00

abstract：:Carcinoma showing thymic-like differentiation (CASTLE) is a rare tumour of the thyroid, which arises from ectopic thymic tissue or remnants of branchial pouches. A systematic review of English literature evidences less than thirty cases; from them, it clearly appears that CASTLE is considered an indolent slow-growing ...

journal_title：Endocrine journal

authors： Cappelli C,Tironi A,Marchetti GP,Pirola I,De Martino E,Delbarba A,Castellano M,Rosei EA

更新日期：2008-08-01 00:00:00

abstract：:The present study used intermittently scanned continuous glucose monitoring (isCGM) in 10 patients with type 1 diabetes mellitus (T1DM) to evaluate the efficacy and safety of 7-day outpatient treatment with the combination of intensive insulin therapy and sodium-glucose transporter 2 inhibitor (SGLT2-I). All participa...

journal_title：Endocrine journal

authors： Kurozumi A,Okada Y,Tanaka Y

更新日期：2020-11-18 00:00:00

abstract：:It has been reported that there is an inverse relationship between serum sodium (Na) and potassium (K) levels in patients with diabetic coma. The present study was undertaken to determine whether such an inverse relation depends upon plasma glucose levels in diabetic patients for their glycemic control. We examined tw...

journal_title：Endocrine journal

authors： Saito T,Ishikawa S,Higashiyama M,Nakamura T,Rokkaku K,Hayashi H,Kusaka I,Nagasaka S,Saito T

更新日期：1999-02-01 00:00:00

abstract：:The renin-angiotensin system (RAS) has been unequivocally implicated as a mediator of diabetic complications. The present study was designed to evaluate the RAS in non-insulin dependent diabetic patients with diabetic nephropathy. Plasma renin activity, plasma angiotensin II and serum angiotensin-converting enzyme (AC...

journal_title：Endocrine journal

authors： Nicola W,Sidhom G,El Khyat Z,Ibrahim S,Salah A,El Sayed A

更新日期：2001-02-01 00:00:00

abstract：:Since 1989, neonatal mass screening for congenital adrenal hyperplasia (CAH) has been carried out in Japan. The mass screening has detected not only the patients with the classic form of steroid 21-hydroxylase deficiency (21-OHD), but also those with the nonclassic (NC) form of 21-OHD, and the molecular basis in these...

journal_title：Endocrine journal

authors： Shinagawa T,Horikawa R,Isojima T,Naiki Y,Tanaka T,Katsumata N

更新日期：2007-12-01 00:00:00

abstract：:The present study was undertaken to determine pathophysiology of body water control in hypernatremic subjects with hypothalamic space-occupying lesions. Eight subjects with hypothalamic space-occupying lesions were divided into two groups of hypernatremia in the presence or absence of body water deficit. In 5 dehydrat...

journal_title：Endocrine journal

authors： Hayashi T,Murata M,Saito T,Ikoma A,Tamemoto H,Kawakami M,Ishikawa SE

更新日期：2008-08-01 00:00:00

abstract：:Differentiated thyroid carcinoma (DTC) is generally indolent in nature and, even though it metastasizes to distant organs, the prognosis is normally excellent. In contrast, the overall survival (OS) of patients with radioactive iodine (RAI)-refractory and progressive metastases is dire, because no effective therapies ...

journal_title：Endocrine journal

authors： Ito Y,Suzuki S,Ito K,Imai T,Okamoto T,Kitano H,Sugitani I,Sugino K,Tsutsui H,Hara H,Yoshida A,Shimizu K

更新日期：2016-07-30 00:00:00

abstract：:To evaluate the clinical usefulness of serum soluble Fas (sFas) and sFas ligand as a prognostic factor and for monitoring the regression and progression of metastatic prostate cancer treated with endocrine therapy, sFas and sFas ligand were measured in sera collected from 30 patients with untreated metastatic prostate...

journal_title：Endocrine journal

authors： Furuya Y,Nagakawa O,Fuse H

更新日期：2003-10-01 00:00:00

abstract：:Erythropoietin (EPO) is known to stimulate erythropoiesis after binding with its specific receptor. In clinics, EPO is widely used in hemodialyzed patients with diabetes. However, changes in the expression of the erythropoietin receptor (EPOR) under diabetic conditions are still unclear. Therefore, we investigated EPO...

journal_title：Endocrine journal

authors： Kuo SC,Li Y,Cheng KC,Niu CS,Cheng JT,Niu HS

更新日期：2018-02-26 00:00:00

abstract：:Multiple endocrine neoplasia type 1 (MEN 1) is rarely reported in Japanese and other oriental populations. To examine if there is a racial difference in the prevalence of MEN 1, we initiated extensive work on patients with endocrine tumors for additional lesions, and annual screening of family members of affected pati...

journal_title：Endocrine journal

authors： Katai M,Sakurai A,Itakura Y,Ikeo Y,Nakajima K,Hara M,Iijima S,Kaneko T,Kobayashi M,Ichikawa K,Aizawa T,Hashizume K

更新日期：1997-12-01 00:00:00

abstract：:An open-label prospective cross-over trial was performed to compare the efficacy and adverse effects of nateglinide with those of voglibose on Japanese early type 2 diabetes (who were oral hypoglycemic agent naïve and whose HbA(1C) levels were between 7.0 and 7.9% before treatment). Fourteen patients received 270 mg/d...

journal_title：Endocrine journal

authors： Kurebayashi S,Watada H,Tanaka Y,Kawasumi M,Kawamori R,Hirose T

更新日期：2006-04-01 00:00:00

abstract：:A 14-year-old girl was referred to our department because of headache and visual impairment following the resection of recurrent cardiac myxoma. Head magnetic resonance imaging (MRI) scan detected an intra- and supra-sellar tumor. Moreover, the patient showed the presence of spotty skin pigmentations on her cheeks and...

journal_title：Endocrine journal

authors： Naito Y,Mori J,Tazoe J,Tomida A,Yagyu S,Nakajima H,Iehara T,Tatsuzawa K,Mukai T,Hosoi H

更新日期：2019-12-25 00:00:00

abstract：:We report on two siblings with classic simple virilizing 21-hydroxylase deficiency whose neonatal screening for serum 17alpha-hydroxyprogesterone (17-OHP) gave normal results. The proband, a girl with clitoromegaly whose screening 17-OHP value had been 9.2 ng/ml, was diagnosed at the age of 6 months, and her elder bro...

journal_title：Endocrine journal

authors： Shinohara O,Ishiguro H,Shinagawa T,Kubota C

更新日期：1998-06-01 00:00:00

abstract：:Effects of reserpine treatment, not associated with pituitary irradiation, on the pituitary-adrenocortical axis in a total of 37 untreated patients with Cushing's disease were evaluated. With short-term treatment (2 mg daily for 2 weeks, n = 36), basal excretion of urinary 17-OHCS significantly decreased from 11.2 +/-...

journal_title：Endocrine journal

authors： Minamori Y,Yasuda K,Murayama M,Morita H,Yamakita N,Miura K

更新日期：1993-10-01 00:00:00

abstract：:To explore the relationship between serum thyrotropin and components of metabolic syndrome in a Chinese cohort. A total of 1534 adult inhabitants in DaDong district of Shenyang were asked to fulfill the questionnaire, complete physical examination and OGTT. Blood samples were collected to test thyrotropin (TSH), fasti...

journal_title：Endocrine journal

authors： Lai Y,Wang J,Jiang F,Wang B,Chen Y,Li M,Liu H,Li C,Xue H,Li N,Yu J,Shi L,Bai X,Hou X,Zhu L,Lu L,Wang S,Xing Q,Teng X,Teng W,Shan Z

更新日期：2011-01-01 00:00:00

abstract：:Previously, we reported that short-term continuous glucose monitoring (CGM) with the professional iPro2© CGM device is a good clinical indicator of glycated hemoglobin (HbA1c) levels. However, there was no significant correlation between CGM and HbA1c levels when HbA1c levels were >8.0%. To further investigate this is...

journal_title：Endocrine journal

authors： Yamada M,Okada S,Oda H,Nakajima Y,C Bastie C,Kasai Y,Osaki A,Shimoda Y,Shibusawa R,Uehara R,Saito T,Ozawa A,Yamada E

更新日期：2020-05-28 00:00:00

abstract：:Tumor necrosis factor-alpha (TNF-alpha) in placenta is believed to be involved in pathogenesis of intrauterine growth restriction. In contrast, insulin-like growth factors (IGFs) are believed to be important for stimulation of fetal and placental growth. IGF-I stimulates metabolic and growth-promoting actions directly...

journal_title：Endocrine journal

authors： Hashimoto R,Sakai K,Matsumoto H,Iwashita M

更新日期：2010-01-01 00:00:00

abstract：:Genetic linkage analyses have traced the loci for multiple endocrine neoplasia type 2A (MEN 2A) to an interval on chromosome 10q11.2. This region encompasses the RET proto-oncogene, a receptor tyrosine kinase gene expressed in medullary thyroid carcinoma (MTC) and pheochromocytoma. By means of genomic polymerase chain...

journal_title：Endocrine journal

authors： Oishi S,Sato T,Takiguchi-Shirahama S,Nakamura Y

更新日期：1995-08-01 00:00:00