Abstract:
:Multiple endocrine neoplasia type 1 (MEN 1) is rarely reported in Japanese and other oriental populations. To examine if there is a racial difference in the prevalence of MEN 1, we initiated extensive work on patients with endocrine tumors for additional lesions, and annual screening of family members of affected patients. In a four-year study, eleven asymptomatic patients were found by family screening, and the number of patients with MEN 1 in our clinics increased from 16 to 38. Estimated prevalence of MEN 1 was no less than 0.018/1000. MEN 1 may not be as rare as had been thought in Japanese, and the prevalence of MEN 1 in Japanese would not be significantly different from that of Caucasians. Systemic surveillance and extensive screening of family members are required for early detection and management of patients.
journal_name
Endocr Jjournal_title
Endocrine journalauthors
Katai M,Sakurai A,Itakura Y,Ikeo Y,Nakajima K,Hara M,Iijima S,Kaneko T,Kobayashi M,Ichikawa K,Aizawa T,Hashizume Kdoi
10.1507/endocrj.44.841subject
Has Abstractpub_date
1997-12-01 00:00:00pages
841-5issue
6eissn
0918-8959issn
1348-4540journal_volume
44pub_type
杂志文章abstract::To assess the total daily inulin dose (TDD) and contribution of basal insulin to TDD and to identify the predictive factors for insulin requirement profiles in subjects with type 2 diabetes, we retrospectively examined insulin requirement profiles of 275 hospitalized subjects treated with basal-bolus insulin therapy (...
journal_title:Endocrine journal
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journal_title:Endocrine journal
pub_type: 杂志文章
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journal_title:Endocrine journal
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journal_title:Endocrine journal
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更新日期:2012-01-01 00:00:00
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