Neurocognitive processes of linguistic cues related to death.

Abstract:

:Consciousness of the finiteness of one's personal existence influences human thoughts and behaviors tremendously. However, the neural substrates underlying the processing of death-related information remain unclear. The current study addressed this issue by scanning 20 female adults, using functional magnetic resonance imaging, in a modified Stroop task that required naming colors of death-related, negative-valence, and neutral-valence words. We found that, while both death-related and negative-valence words increased activity in the precuneus/posterior cingulate and lateral frontal cortex relative to neutral-valence words, the neural correlate of the processing of death-related words was characterized by decreased activity in bilateral insula relative to both negative-valence and neutral-valence words. Moreover, the decreased activity in the left insula correlated with subjective ratings of death relevance of death-related words and the decreased activity in the right insula correlated with subjective ratings of arousal induced by death-related words. Our fMRI findings suggest that, while both death-related and negative-valence words are associated with enhanced arousal and emotion regulation, the processing of linguistic cues related to death is associated with modulations of the activity in the insula that mediates neural representation of the sentient self.

journal_name

Neuropsychologia

journal_title

Neuropsychologia

authors

Han S,Qin J,Ma Y

doi

10.1016/j.neuropsychologia.2010.07.026

subject

Has Abstract

pub_date

2010-10-01 00:00:00

pages

3436-42

issue

12

eissn

0028-3932

issn

1873-3514

pii

S0028-3932(10)00321-0

journal_volume

48

pub_type

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