Abstract:
:Findings of pharmacological studies that have investigated the involvement of specific regions of the brain in recognition memory are reviewed. The particular emphasis of the review concerns what such studies indicate concerning the role of the perirhinal cortex in recognition memory. Most of the studies involve rats and most have investigated recognition memory for objects. Pharmacological studies provide a large body of evidence supporting the essential role of the perirhinal cortex in the acquisition, consolidation and retrieval of object recognition memory. Such studies provide increasingly detailed evidence concerning both the neurotransmitter systems and the underlying intracellular mechanisms involved in recognition memory processes. They have provided evidence in support of synaptic weakening as a major synaptic plastic process within perirhinal cortex underlying object recognition memory. They have also supplied confirmatory evidence that that there is more than one synaptic plastic process involved. The demonstrated necessity to long-term recognition memory of intracellular signalling mechanisms related to synaptic modification within perirhinal cortex establishes a central role for the region in the information storage underlying such memory. Perirhinal cortex is thereby established as an information storage site rather than solely a processing station. Pharmacological studies have also supplied new evidence concerning the detailed roles of other regions, including the hippocampus and the medial prefrontal cortex in different types of recognition memory tasks that include a spatial or temporal component. In so doing, they have also further defined the contribution of perirhinal cortex to such tasks. To date it appears that the contribution of perirhinal cortex to associative and temporal order memory reflects that in simple object recognition memory, namely that perirhinal cortex provides information concerning objects and their prior occurrence (novelty/familiarity).
journal_name
Neuropsychologiajournal_title
Neuropsychologiaauthors
Brown MW,Barker GR,Aggleton JP,Warburton ECdoi
10.1016/j.neuropsychologia.2012.07.034subject
Has Abstractpub_date
2012-11-01 00:00:00pages
3122-40issue
13eissn
0028-3932issn
1873-3514pii
S0028-3932(12)00330-2journal_volume
50pub_type
杂志文章,评审相关文献
NEUROPSYCHOLOGIA文献大全abstract::Several neuroimaging studies showed that fulfilled expectations increase the magnitude of repetition suppression (RS) in the face-selective visual cortex. However, previous fMRI studies did not allow a distinction between the reductions of the response due to stimulus repetitions and fulfilled expectations (expectatio...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2014.12.017
更新日期:2015-01-01 00:00:00
abstract::In order to determine the neural substrates of phonemic coding during both listening and speaking, we used a repetition suppression (RS) paradigm in which vowels were repeatedly perceived or produced while measuring BOLD activity with sparse sampling functional magnetic resonance imaging (fMRI). RS refers to the pheno...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2019.107267
更新日期:2020-01-01 00:00:00
abstract::We examined the effects of emotional stimuli on right and left hemisphere detection performance in a hemifield visual discrimination task. A group of 18 healthy subjects were asked to discriminate between upright and inverted triangles (target). Targets were randomly presented in the left or right visual hemifield (15...
journal_title:Neuropsychologia
pub_type: 临床试验,杂志文章
doi:10.1016/s0028-3932(00)00072-5
更新日期:2000-01-01 00:00:00
abstract::Intentions are commonly conceived of as discrete mental states that are the direct cause of actions. In the last several decades, neuroscientists have taken up the project of finding the neural implementation of intentions, and a number of areas have been posited as implementing these states. We argue, however, that t...
journal_title:Neuropsychologia
pub_type: 杂志文章,评审
doi:10.1016/j.neuropsychologia.2014.01.010
更新日期:2014-04-01 00:00:00
abstract::Studies of remote memory for semantic facts and concepts suggest that hippocampal lesions lead to a temporally graded impairment that extends no more than ten years prior to the onset of amnesia. Such findings have led to the notion that once consolidated, semantic memories are represented neocortically and are no lon...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2014.06.018
更新日期:2014-08-01 00:00:00
abstract::Episodic memory provides information about the "when" of events as well as "what" and "where" they happened. Using functional imaging, we investigated the domain specificity of retrieval-related processes following encoding of complex, naturalistic events. Subjects watched a 42-min TV episode, and 24h later, made disc...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2012.07.025
更新日期:2012-10-01 00:00:00
abstract::Forty-three consecutively admitted Parkinsonian patients, of whom over a third had undergone stereotactic surgery about a decade previously, and a small control group were given a confrontation naming task. A number of comparisons were made, under the rubrics of success in naming, types of error and response latency, ...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/0028-3932(86)90012-6
更新日期:1986-01-01 00:00:00
abstract::This experiment investigated dynamic gender-related differences in perceptual asymmetry (PA) in a dichotic task. Twenty right-handed males and 20 right-handed females performed a 200 trial directed attention dichotic listening task using consonant-vowel-consonant nonsense syllables. Men showed a greater right-ear adva...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/0028-3932(93)90158-v
更新日期:1993-04-01 00:00:00
abstract::Mimicry has been suggested to function as a "social glue", a key mechanism that helps to build social rapport. It leads to increased feeling of closeness toward the mimicker as well as greater liking, suggesting close bidirectional links with reward. In recent work using eye-gaze tracking, we have demonstrated that th...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2017.08.018
更新日期:2018-07-31 00:00:00
abstract::Difficulty interpreting facial expressions has been reported in autism spectrum disorders (ASD) and is thought to be associated with amygdala abnormalities. To further explore the neural basis of abnormal emotional face processing in ASD, we conducted an fMRI study of emotional face matching in high-functioning adults...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2010.07.022
更新日期:2010-10-01 00:00:00
abstract::Fluid intelligence is a crucial cognitive ability that predicts key life outcomes across the lifespan. Strong empirical links exist between fluid intelligence and processing speed on the one hand, and white matter integrity and processing speed on the other. We propose a watershed model that integrates these three exp...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2016.08.008
更新日期:2016-10-01 00:00:00
abstract::Functional brain asymmetries in semantic activation were studied by presenting categorically related (e.g. TABLE-BED) or unrelated primes and targets to the left visual field (LVF)/right hemisphere or to the right visual field (RVF)/left hemisphere in the single word presentation lexical decision task. The results sho...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/s0028-3932(01)00151-8
更新日期:2002-01-01 00:00:00
abstract::The HERA (Hemispheric Encoding/Retrieval Asymmetry) model captures hemispheric lateralization of prefrontal cortex (PFC) brain activity during memory encoding and retrieval. Reduced HERA has been observed in cross-sectional aging studies, but there is no longitudinal evidence, to our knowledge, on age-related changes ...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2019.107329
更新日期:2020-02-03 00:00:00
abstract::Although imaging studies have indicated that the fusiform gyrus is important in tasks of picture naming, whether this region encodes an object's structure or its meaning is not clear. We used positron emission tomography to examine cerebral blood flow (CBF) changes in response to a picture naming task that varied on t...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/s0028-3932(01)00083-5
更新日期:2002-01-01 00:00:00
abstract::Recent work shows that vividly imagining oneself helping others in situations of need (episodic simulation) increases one's willingness to help. The mechanisms underlying this effect are unclear, though it is known that the medial temporal lobe (MTL) is critical for supporting episodic simulation in general. Therefore...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2019.107243
更新日期:2019-12-01 00:00:00
abstract::Self-knowledge concerns one's own preferences and personality. It pertains to the self (similar to episodic memory), yet does not concern events. It is factual (like semantic memory), but also idiosyncratic. For these reasons, it is unclear where self-knowledge might fall on a continuum in relation to semantic and epi...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2017.10.024
更新日期:2018-02-01 00:00:00
abstract::A critical issue related to the notion of identity concerns our ability to discriminate between internally and externally generated stimuli. This basic mechanism likely relies on perceptual and motor information, and requires that both motor plans and the resulting activity be continuously mapped on a reliable body re...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2009.10.008
更新日期:2010-02-01 00:00:00
abstract::Following the princeps investigations of Marc Jeannerod on action-perception, specifically, goal-directed movement, this review article addresses visual and non-visual processes involved in guiding the hand in reaching or grasping tasks. The contributions of different sources of correction of ongoing movements are con...
journal_title:Neuropsychologia
pub_type: 杂志文章,评审
doi:10.1016/j.neuropsychologia.2013.12.005
更新日期:2014-03-01 00:00:00
abstract::The vestibular system contributes to a wide range of functions, from postural and oculomotor reflexes to spatial representation and cognition. Vestibular signals are important to maintain an internal, updated representation of the body position and movement in space. However, it is not clear to what extent they are al...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2011.07.026
更新日期:2011-09-01 00:00:00
abstract::Previous research has suggested that bilinguals may exhibit cognitive advantages over those who are monolingual, although conflicting results have been reported. This advantage may be heightened in older adults, because of age-related cognitive decline. However, the effects of bilingualism on working memory performanc...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2020.107468
更新日期:2020-06-01 00:00:00
abstract::Effects of closed head injury (CHI) severity, focal brain lesions, and age at injury on word fluency (WF) were studied longitudinally in 122 children (78 severe, 44 mild); 112 CHI patients (68 severe, 44 mild CHI) and 104 uninjured normal controls participated in a cross-sectional study. WF was measured by asking the ...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/s0028-3932(00)00111-1
更新日期:2001-01-01 00:00:00
abstract::MRI leukoaraiosis (LA) is less likely to interfere with simple compared to more complex working memory (WM) skills. We hypothesize that LA within the left hemisphere negatively impacts higher-level WM processes in dementia. Participants with dementia (n=64; MMSE=22.0+/-3.4) performed a Backward Digit Task measuring si...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2008.04.007
更新日期:2008-08-01 00:00:00
abstract::Previous research has suggested a time-of-day effect for response inhibition on a task known to be dependent on frontal lobe function. We used a forced desynchronisation protocol to separate effects of circadian and sleep homeostat processes on a modified version of this task. Fourteen healthy young adults followed an...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2006.12.012
更新日期:2007-04-09 00:00:00
abstract::Our perceptual systems integrate multisensory information about objects that are close to our bodies, which allow us to respond quickly and appropriately to potential threats, as well as act upon and manipulate useful tools. Intriguingly, the representation of this area close to our body, known as the multisensory 'pe...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2014.10.027
更新日期:2015-04-01 00:00:00
abstract::An extensive network of cortical areas is involved in multisensory object and action recognition. This network draws on inferior frontal, posterior temporal, and parietal areas; activity is modulated by familiarity and the semantic congruency of auditory and visual component signals even if semantic incongruences are ...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2013.05.014
更新日期:2013-08-01 00:00:00
abstract::The primary visual cortex (V1) has been shown to be critical for visual awareness, but the importance of other low-level visual areas has remained unclear. To clarify the role of human cortical area V2 in visual awareness, we applied transcranial magnetic stimulation (TMS) over V2 while participants were carrying out ...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2012.03.015
更新日期:2012-06-01 00:00:00
abstract::First language (L1) attrition is a socio-linguistic circumstance where second language (L2) learning coincides with changes in exposure and use of the native-L1. Attriters often report experiencing a decline in automaticity or proficiency in their L1 after a prolonged period in the L2 environment, while their L2 profi...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2016.10.007
更新日期:2016-12-01 00:00:00
abstract::Psychological well-being and social acumen benefit from the recognition of humourous intent and its enjoyment. The enjoyment of humour requires recognition, but humour recognition is not necessarily accompanied by humour enjoyment. Humour recognition is crucial during social interactions, while the associated enjoymen...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2015.10.013
更新日期:2015-12-01 00:00:00
abstract::The functional-neuroanatomic relationship that describes the involvement of the parietal cortex in visual search was investigated using repetitive transcranial magnetic stimulation (rTMS; 10 Hz, 500 ms in duration). Twelve adult participants performed feature-based visual search for a unique letter-without eye movemen...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2005.07.014
更新日期:2006-01-01 00:00:00
abstract::Musical melodies have "peaks" and "valleys". Although the vertical component of pitch and music is well-known, the mechanisms underlying its mental representation still remain elusive. We show evidence regarding the importance of previous experience with melodies for crossmodal interactions to emerge. The impact of th...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2018.05.009
更新日期:2018-08-01 00:00:00