Neuronavigated transcranial magnetic stimulation suggests that area V2 is necessary for visual awareness.

Abstract:

:The primary visual cortex (V1) has been shown to be critical for visual awareness, but the importance of other low-level visual areas has remained unclear. To clarify the role of human cortical area V2 in visual awareness, we applied transcranial magnetic stimulation (TMS) over V2 while participants were carrying out a visual discrimination task and rating their subjective awareness. Individual retinotopic maps and modelling of the TMS-induced electric field in V1, V2 and V3d ensured that the electric field was at or under the phosphene threshold level in V1 and V3d, whereas in V2 it was at the higher suppressive level. As earlier shown for the V1, our results imply that also V2 is necessary for conscious visual experience. Visual awareness of stimulus presence was completely suppressed when the TMS pulse was delivered 44-84 ms after the onset of visual stimulus. Visual discrimination and awareness of stimulus features was impaired when the TMS pulse was delivered 44-104 ms after the visual stimulus onset. These results suggest that visual awareness cannot be generated without an intact V2.

journal_name

Neuropsychologia

journal_title

Neuropsychologia

authors

Salminen-Vaparanta N,Koivisto M,Noreika V,Vanni S,Revonsuo A

doi

10.1016/j.neuropsychologia.2012.03.015

subject

Has Abstract

pub_date

2012-06-01 00:00:00

pages

1621-7

issue

7

eissn

0028-3932

issn

1873-3514

pii

S0028-3932(12)00132-7

journal_volume

50

pub_type

杂志文章
  • Mesolimbic interaction of emotional valence and reward improves memory formation.

    abstract::Animal studies suggest that dopaminergic neuromodulation is critical for hippocampal memory formation. Compatible with this notion, recent functional imaging evidence in humans showed that reward modulates the hippocampus-dependent formation of episodic memories through activation of areas belonging to the mesolimbic ...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2007.11.020

    authors: Wittmann BC,Schiltz K,Boehler CN,Düzel E

    更新日期:2008-03-07 00:00:00

  • Pattern span: a tool for unwelding visuo-spatial memory.

    abstract::Evidence showing that non-verbal short-term memory has distinct visual and spatial/sequential components is reviewed. A new test, The Visual Patterns Test (VPT), which was designed to measure short-term visual memory largely shorn of its spatio-sequential component, is described. Correlational studies of the VPT and t...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/s0028-3932(98)00159-6

    authors: Della Sala S,Gray C,Baddeley A,Allamano N,Wilson L

    更新日期:1999-09-01 00:00:00

  • The effects of TMS over dorsolateral prefrontal cortex on trans-saccadic memory of multiple objects.

    abstract::Humans typically make several rapid eye movements (saccades) per second. It is thought that visual working memory can retain and spatially integrate three to four objects or features across each saccade but little is known about this neural mechanism. Previously we showed that transcranial magnetic stimulation (TMS) t...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2014.08.025

    authors: Tanaka LL,Dessing JC,Malik P,Prime SL,Crawford JD

    更新日期:2014-10-01 00:00:00

  • Continuous theta-burst stimulation to primary motor cortex reduces the overproduction of forces following removal of visual feedback.

    abstract::Forward models, generated from the efference copies of motor commands, are thought to monitor the accuracy of ongoing movement. By comparing predicted with actual afferent information, forward models also aid in the differentiation of self-produced movements from externally generated ones. Many have proposed that a co...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2011.06.023

    authors: Therrien AS,Richardson BA,Balasubramaniam R

    更新日期:2011-08-01 00:00:00

  • Lexical access versus lexical decision processes for auditory, visual, and audiovisual items: Insights from behavioral and neural measures.

    abstract::In two experiments, we investigated the relationship between lexical access processes, and processes that are specifically related to making lexical decisions. In Experiment 1, participants performed a standard lexical decision task in which they had to respond as quickly and as accurately as possible to visual (writt...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2019.107305

    authors: López Zunini RA,Baart M,Samuel AG,Armstrong BC

    更新日期:2020-02-03 00:00:00

  • Automatic statistical processing of visual properties in simultanagnosia.

    abstract::Previous research has suggested that, when operating in a distributed attention mode, the visual system automatically represents visual displays by their overall statistics, rather than their individual properties. Recent neuropsychological work shows partly preserved distributed attention in simultanagnosic patients,...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2008.05.014

    authors: Demeyere N,Rzeskiewicz A,Humphreys KA,Humphreys GW

    更新日期:2008-09-01 00:00:00

  • Looking for episodic memory in animals and young children: prospects for a new minimalism.

    abstract::Because animals and young children cannot be interrogated about their experiences it is difficult to conduct research into their episodic memories. The approach to this issue adopted by Clayton and Dickinson [Clayton, N. S., & Dickinson, A. (1998). Episodic-like memory during cache recovery by scrub jays. Nature, 395,...

    journal_title:Neuropsychologia

    pub_type: 杂志文章,评审

    doi:10.1016/j.neuropsychologia.2008.10.011

    authors: Clayton NS,Russell J

    更新日期:2009-09-01 00:00:00

  • Are incongruent objects harder to identify? The functional significance of the N300 component.

    abstract::Objects in the real world typically appear within a broader context, having relationships with the environment. Do these relations between objects and the contexts in which they appear affect object identification? Previous findings of an N300 component evoked by scene-incongruent objects were taken as evidence for su...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2018.06.004

    authors: Truman A,Mudrik L

    更新日期:2018-08-01 00:00:00

  • Stress-evoking emotional stimuli exaggerate deficits in motor function in Parkinson's disease.

    abstract::Recent animal studies have shown that stress can profoundly affect motor behaviour and worsen motor deficits associated with Parkinson's disease (PD) by acting on the dopaminergic system, possibly due to stress-associated emotional changes. However, systematic investigation of the influence of acute emotional stressor...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2018.03.006

    authors: Blakemore RL,MacAskill' MR,Shoorangiz R,Anderson TJ

    更新日期:2018-04-01 00:00:00

  • Building the multitasking brain: An integrated perspective on functional brain activation during task-switching and dual-tasking.

    abstract::Multitasking behavior is associated with well-known performance costs, but the question of why individuals falter when attempting to manage multiple streams of information remains difficult to answer. One reason for this difficulty may be that multitasking costs are often characterized by isolating component processes...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2019.107149

    authors: Ward N,Hussey EK,Cunningham EC,Paul EJ,McWilliams T,Kramer AF

    更新日期:2019-09-01 00:00:00

  • Use of left vs right hand in responding to lateralized stimuli in unilateral neglect.

    abstract::Previous research suggests that contralesional limb activation may reduce the degree of visual neglect shown by hemi-inattentive subjects. The present study examines whether minimal assisted-left-limb activation (pressing a response key with the hemiplegic hand, aided by the ipsilesional hand) resulted in lowered resp...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/0028-3932(91)90082-j

    authors: Robertson I

    更新日期:1991-01-01 00:00:00

  • Prospective memory in patients with closed head injury: a review.

    abstract::This paper aimed to review the limited, but growing literature on prospective memory (PM) following closed head injury (CHI). Search of two commonly used databases yielded studies that could be classified as: self- or other-report of PM deficits; behavioral PM measures in adults with CHI, behavioral PM measures in chi...

    journal_title:Neuropsychologia

    pub_type: 杂志文章,评审

    doi:10.1016/j.neuropsychologia.2011.02.006

    authors: Shum D,Levin H,Chan RC

    更新日期:2011-07-01 00:00:00

  • Effects of brief imitative experience on EEG desynchronization during action observation.

    abstract::There is a good deal of evidence that observing the actions of other people is associated with activation of the observer's motor system, which may reflect involvement of the mirror neuron system (MNS) in certain aspects of action processing in humans. Furthermore, variation in the extent of this activation appears to...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2009.03.022

    authors: Marshall PJ,Bouquet CA,Shipley TF,Young T

    更新日期:2009-08-01 00:00:00

  • Neural responses elicited to face motion and vocalization pairings.

    abstract::During social interactions our brains continuously integrate incoming auditory and visual input from the movements and vocalizations of others. Yet, the dynamics of the neural events elicited to these multisensory stimuli remain largely uncharacterized. Here we recorded audiovisual scalp event-related potentials (ERPs...

    journal_title:Neuropsychologia

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.neuropsychologia.2006.04.017

    authors: Puce A,Epling JA,Thompson JC,Carrick OK

    更新日期:2007-01-07 00:00:00

  • Subthalamic deep brain stimulation influences complex emotional musical experience in Parkinson's disease.

    abstract::Subthalamic deep brain stimulation (STN DBS) is an effective treatment for reducing the motor symptoms of patients with Parkinson's disease (PD), but several side effects have been reported, concerning the processing of emotions. Music has been shown to evoke powerful emotional experiences - not only basic emotions, b...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2018.06.018

    authors: Trost W,Leh F,Houvenaghel JF,Choppin S,Drapier S,Sauleau P,Haegelen C,Robert G,Grandjean D,Vérin M

    更新日期:2018-08-01 00:00:00

  • Recall of remote episodic memories can appear deficient because of a gist-based retrieval orientation.

    abstract::Determining whether patients with amnesia can succeed in remembering their distant past has pivotal implications for theories of memory storage. However, various factors influence recall. We speculated that some patients with anterograde amnesia adopt a gist-based retrieval orientation for memories from all time perio...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2008.12.006

    authors: Rudoy JD,Weintraub S,Paller KA

    更新日期:2009-02-01 00:00:00

  • How reliable are occipital asymmetry measurements?

    abstract::In vivo occipital asymmetry (OA) measurements have been used to infer functional asymmetries such as language dominance. We investigated the degree of correlation between OA measurements derived by the same rater from different scans of the same subject. We used magnetic resonance (MR) and computerized axial tomograph...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/0028-3932(94)90122-8

    authors: Chu CC,Tranel D,Damasio H

    更新日期:1994-12-01 00:00:00

  • Paralexic errors in Broca's and Wernicke's aphasia.

    abstract::Paralexic speech errors were examined during the oral reading of sentences for 12 right-handed adults, including four Broca's aphasics, four Wernicke's aphasics and four patients with unilateral right-hemisphere lesions. A category system of error types was developed, and 129 errors were analyzed in terms of identifia...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/0028-3932(85)90011-9

    authors: Payne M,Cooper WE

    更新日期:1985-01-01 00:00:00

  • Subclassification of non-pathological left-handers poses problems for theories of handedness.

    abstract::The throwing performance of 104 right-handers, and 96 left-handers with inconsistent and consistent hand preferences, as classified by the procedure used by Ponton (Neuropsychologia 25, 305-311, 1987), was examined. Left-handers with inconsistent hand preference write with the left, tap faster with the left, and perfo...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/0028-3932(90)90021-f

    authors: Peters M

    更新日期:1990-01-01 00:00:00

  • A Bird's eye view from below: Activity in the temporo-parietal junction predicts from-above Necker Cube percepts.

    abstract::The temporo-parietal junction (TPJ) consistently emerges in other-regarding behavior, including tasks probing affective phenomena such as morality and empathy. Yet the TPJ is also recruited in processes with no affective or social component, such as visuo-spatial processing and mathematical cognition. We present seren...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2020.107654

    authors: Loued-Khenissi L,Preuschoff K

    更新日期:2020-12-01 00:00:00

  • A Ponzo-like illusion left and right of fixation: a failed prediction.

    abstract::Ponzo-like figures, with two parallel horizontal test lines superimposed on a pattern of converging background lines suggesting either a floor or a ceiling were presented in a tachistoscope unpredictably left or right of fixation, and the subjects had to compare the test lines as to length. The classical relative over...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/0028-3932(83)90105-7

    authors: Bertelson P,Morais J

    更新日期:1983-01-01 00:00:00

  • Fear-related signals are prioritised in visual, somatosensory and spatial systems.

    abstract::The human brain has evolved a multifaceted fear system, allowing threat detection to enable rapid adaptive responses crucial for survival. Although many cortical and subcortical brain areas are believed to be involved in the survival circuits detecting and responding to threat, the amygdala has reportedly a crucial ro...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2020.107698

    authors: Bertini C,Làdavas E

    更新日期:2020-11-27 00:00:00

  • No effect of vocabulary reactivation in older adults.

    abstract::Quality of memory and sleep declines with age. However, the mechanistic interactions underlying the memory function of sleep in older adults are still unknown. It is widely assumed that the beneficial effect of sleep on memory relies on reactivation during Non-rapid eye movement (NREM) sleep. Targeting these reactivat...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2018.08.021

    authors: Cordi MJ,Schreiner T,Rasch B

    更新日期:2018-10-01 00:00:00

  • Recognition and naming of famous faces in Alzheimer's disease: a cognitive analysis.

    abstract::A Famous Faces Test designed to assess face recognition, spontaneous naming, verbal identification of un-named faces, and cued naming using semantic and phonetic cues was administered to 22 patients with dementia of Alzheimer type (DAT) and 25 matched controls. The DAT patients were significantly impaired in all test ...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/0028-3932(93)90128-m

    authors: Hodges JR,Salmon DP,Butters N

    更新日期:1993-08-01 00:00:00

  • The prediction of normal P3 latency and the diagnosis of dementia.

    abstract::The relationship between age and the latency of the P3 (auditory evoked response potential) component was best described in 55 normals aged 15-89 by separate linear regression equations for those younger and those older than 63. Twelve out of 19 patients with dementia had P3 latencies at FZ and CZ which were delayed b...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/0028-3932(86)90081-3

    authors: Gordon E,Kraiuhin C,Stanfield P,Meares R,Howson A

    更新日期:1986-01-01 00:00:00

  • Dissociable effects of phonetic competition and category typicality in a phonetic categorization task: an fMRI investigation.

    abstract::The current study used fMRI to explore the extent to which neural activation patterns in the processing of speech are driven by the quality of a speech sound as a member of its phonetic category, that is, its category typicality, or by the competition inherent in resolving the category membership of stimuli which are ...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2006.11.005

    authors: Myers EB

    更新日期:2007-04-08 00:00:00

  • Morphological complexity and cerebral lateralization.

    abstract::Fifteen agentive nouns, all with meanings derivable from the meaning of the stem verb, were presented tachistoscopically to right-handed subjects. Non-agentive nouns were also presented, and subjects were asked to produce the plural form in addition to the simple stimulus form. The results show a significant right vis...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/0028-3932(84)90083-6

    authors: Goodall G

    更新日期:1984-01-01 00:00:00

  • Attentional and sensory effects of lowered levels of intrinsic alertness.

    abstract::Low levels of intrinsic alertness are associated with lateralized performance in visual tasks, similar to neglect of the left (ipsilesional) visual hemi-field. However, it is unclear whether reduced alertness produces a specific lateralization of spatial-attentional processes in terms of the prioritization of right- o...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2009.08.004

    authors: Matthias E,Bublak P,Costa A,Müller HJ,Schneider WX,Finke K

    更新日期:2009-12-01 00:00:00

  • Deterioration of word meaning: implications for reading.

    abstract::We investigated six patients with progressive focal dementia or progressive aphasia, who showed impairments in knowledge of word meaning ranging from moderate to very severe. In all cases, a test of oral word reading demonstrated preserved reading of words with regular spelling-to-sound correspondences (e.g. MINT), bu...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/0028-3932(92)90096-5

    authors: Patterson K,Hodges JR

    更新日期:1992-12-01 00:00:00

  • Impaired functional differentiation for categories of objects in the ventral visual stream: A case of developmental visual impairment.

    abstract::We report the case of a 14-year-old girl suffering from severe developmental visual impairment along with delayed language and cognitive development, and featuring a clear-cut dissociation between spared dorsal and impaired ventral visual pathways. Visual recognition of objects, including faces and printed words, was ...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2015.08.009

    authors: Martinaud O,Pouliquen D,Parain D,Goldenberg A,Gérardin E,Hannequin D,Altarelli I,Ramus F,Hertz-Pannier L,Dehaene-Lambertz G,Cohen L

    更新日期:2015-10-01 00:00:00