Restitution of visual functions in cerebrally blind children.

Abstract:

:In adult patients who suffer from a visual field defect due to cerebral lesions, visual functions can be restored by systematic visual field training. Such visual field training is not feasible in young, brain-damaged children, who are unable to cooperate like adults. We have already shown earlier [Werth, R., and Moehrenschlager, M. (1999). The development of visual functions in cerebrally blind children during a systematic visual field training. Restorative Neurology and Neuroscience, 15, 229-241.] that systematic visual field training, which requires no ability to understand instructions or to cooperate, is successful in brain-damaged children and may lead to complete recovery of the visual field within 3 months. The present study provides more behavioral evidence and a control of intraocular light scatter. In addition to the earlier study, the luminance difference thresholds in the recovered visual field were compared with those of a normal control group. Seventeen children aged 1-4 years who had been blind for more than 1 year after perinatal asphyxia and two children suffering from homonymous hemianopia due to asphyxic-ischemic lesions participated in systematic visual field training. The functional visual field was assessed with a specially designed arc perimeter. Visual functions developed within a training period of 3 months in 11 children who received visual field training, whereas there was no recovery in the control group (N=37). The findings support the assumption that systematic visual field training facilitates the development of vision in cerebrally blind children. In two children who recovered from blindness, it was shown in functional magnetic resonance imaging (fMRI) that brain tissue in the area of the visual cortex contralateral to the blind visual hemifield was activated by light. In two children suffering from asphyxic-ischemic lesions who did not recover only brain tissue in the area of the visual cortex contralateral to the good visual hemifield could be activated by light. These results support the assumption that activity in spared tissue of the striate and extrastriate visual cortex are a necessary condition for recovery of the visual field in children suffering from cerebral blindness.

journal_name

Neuropsychologia

journal_title

Neuropsychologia

authors

Werth R,Seelos K

doi

10.1016/j.neuropsychologia.2005.03.023

subject

Has Abstract

pub_date

2005-01-01 00:00:00

pages

2011-23

issue

14

eissn

0028-3932

issn

1873-3514

pii

S0028-3932(05)00156-9

journal_volume

43

pub_type

临床试验,杂志文章
  • Agnosia for accents in primary progressive aphasia.

    abstract::As an example of complex auditory signal processing, the analysis of accented speech is potentially vulnerable in the progressive aphasias. However, the brain basis of accent processing and the effects of neurodegenerative disease on this processing are not well understood. Here we undertook a detailed neuropsychologi...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2013.05.013

    authors: Fletcher PD,Downey LE,Agustus JL,Hailstone JC,Tyndall MH,Cifelli A,Schott JM,Warrington EK,Warren JD

    更新日期:2013-08-01 00:00:00

  • Neural systems mediating field and observer memories.

    abstract::Autobiographical memories are more imbued with affect when one adopts a first-person or field perspective during event retrieval, rather than a third-person or observer perspective. We combined fMRI, event narratives, and subjective ratings to identify the neural networks engaged with field versus observer memories fo...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2009.02.019

    authors: Eich E,Nelson AL,Leghari MA,Handy TC

    更新日期:2009-09-01 00:00:00

  • Lateralization of spatial-memory processes: evidence on spatial span, maze learning, and memory for object locations.

    abstract::Spatial memory is one of the most important cognitive functions in daily life, enabling us to locate objects in our environment or to learn a route or a path. In the present study, we elaborated on the hypothesis that human spatial memory consists of multiple sub-processes, relying on different brain structures. There...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/s0028-3932(01)00199-3

    authors: Kessels RP,Jaap Kappelle L,de Haan EH,Postma A

    更新日期:2002-01-01 00:00:00

  • Continuous theta-burst stimulation to primary motor cortex reduces the overproduction of forces following removal of visual feedback.

    abstract::Forward models, generated from the efference copies of motor commands, are thought to monitor the accuracy of ongoing movement. By comparing predicted with actual afferent information, forward models also aid in the differentiation of self-produced movements from externally generated ones. Many have proposed that a co...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2011.06.023

    authors: Therrien AS,Richardson BA,Balasubramaniam R

    更新日期:2011-08-01 00:00:00

  • Incidental and deliberate memory for words and faces after focal cerebral lesions.

    abstract::It was predicted that right-hemisphere lesions cause a more marked deficit of shallow incidental memory than deep incidental or deliberate memory, the degree of the deficits being reversed after left-hemisphere lesions. This hypothesis was studied by measuring memory for words and faces in brain-damaged patients and n...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/0028-3932(87)90133-3

    authors: Vilkki J

    更新日期:1987-01-01 00:00:00

  • Perceptual learning in amnesia.

    abstract::Evidence from experiments on perceptual learning, accumulated during the last few years, increasingly indicates that the relative 'front end' parts of the visual system are more plastic even in adults than was previously expected. Hence, it might be possible that perceptual learning is similar in several respects to p...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/s0028-3932(01)00231-7

    authors: Fahle M,Daum I

    更新日期:2002-01-01 00:00:00

  • Tool use and action planning in apraxia.

    abstract::Apraxia after left inferior parietal lesions has been widely interpreted as evidence of damage or impaired access to representations of tool-use, but most research has investigated pantomime of tool actions, not handling of actual tools. An alternative account is that inferior parietal damage does not affect tool-use ...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2011.01.020

    authors: Sunderland A,Wilkins L,Dineen R

    更新日期:2011-04-01 00:00:00

  • Rightward shift of the auditory subjective straight ahead in right- and left-handed subjects.

    abstract::While spatial asymmetries have been extensively investigated in the visual modality and to a lesser degree in the tactile modality, there are no reports on auditory spatial asymmetries in neurologically normal subjects. The subjects in this study performed an auditory midline task in which they had to adjust the level...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2006.05.027

    authors: Dufour A,Touzalin P,Candas V

    更新日期:2007-01-28 00:00:00

  • Lexical judgments after right- or left-hemisphere injury.

    abstract::Patients with unilateral left- or right-hemisphere lesions were asked to make similarity judgments to visually presented words on the basis of rhyme, meaning or visual similarity. The left-hemisphere-injured group was significantly impaired, relative to controls, for all types of lexical judgments, with the greatest i...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/0028-3932(86)90002-3

    authors: Chiarello C,Church KL

    更新日期:1986-01-01 00:00:00

  • Left anterior cingulate activity predicts intra-individual reaction time variability in healthy adults.

    abstract::Within-subject, or intra-individual, variability in reaction time (RT) is increasingly recognised as an important indicator of the efficiency of attentional control, yet there have been few investigations of the neural correlates of trial-to-trial RT variability in healthy adults. We sought to determine the neural cor...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2015.03.015

    authors: Johnson BP,Pinar A,Fornito A,Nandam LS,Hester R,Bellgrove MA

    更新日期:2015-06-01 00:00:00

  • Timing deficits in attention-deficit/hyperactivity disorder (ADHD): evidence from neurocognitive and neuroimaging studies.

    abstract::Relatively recently, neurocognitive and neuroimaging studies have indicated that individuals with attention-deficit/hyperactivity disorder (ADHD) may have deficits in a range of timing functions and their underlying neural networks. Despite this evidence, timing deficits in ADHD are still somewhat neglected in the lit...

    journal_title:Neuropsychologia

    pub_type: 杂志文章,评审

    doi:10.1016/j.neuropsychologia.2012.09.036

    authors: Noreika V,Falter CM,Rubia K

    更新日期:2013-01-01 00:00:00

  • Agnosia for scenes in topographagnosia.

    abstract::Topographagnosia is most commonly attributed to an agnosia for landmarks. In order to define the nature of this agnosia, we studied a patient with isolated topographic disorientation (TD) after a stroke in the right medial occipitotemporal region. The patient got lost in familiar environments but could readily read an...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/s0028-3932(03)00041-1

    authors: Mendez MF,Cherrier MM

    更新日期:2003-01-01 00:00:00

  • Normal and anomalous development of visual motion processing: motion coherence and 'dorsal-stream vulnerability'.

    abstract::Directional motion processing is a pervasive and functionally important feature of the visual system. Behavioural and VEP studies indicate that it appears as a cortical function after about 7 weeks of age, with global processing, motion based segmentation, and the use of motion in complex perceptual tasks emerging sho...

    journal_title:Neuropsychologia

    pub_type: 杂志文章,评审

    doi:10.1016/s0028-3932(03)00178-7

    authors: Braddick O,Atkinson J,Wattam-Bell J

    更新日期:2003-01-01 00:00:00

  • Parkinson's disease and the control of size and speed in handwriting.

    abstract::This experiment investigated whether Parkinson's disease (PD) patients experience problems in producing stroke size, stroke duration or both, in a handwriting task. Thirteen PD patients and 15 elderly controls wrote four patterns of varying complexity on a digitizer tablet. The participants were instructed to execute ...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/s0028-3932(98)00122-5

    authors: Van Gemmert AW,Teulings HL,Contreras-Vidal JL,Stelmach GE

    更新日期:1999-06-01 00:00:00

  • Brain connectivity in non-reading impaired children and children diagnosed with developmental dyslexia.

    abstract::Diffusion Tensor Imaging (DTI) was used to investigate the relationship between white matter and reading abilities in reading impaired and non-reading impaired children. Seventeen children (7 non-reading impaired, 10 reading impaired) participated in this study. DTI was performed with 2mm isotropic resolution to cover...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2009.03.009

    authors: Odegard TN,Farris EA,Ring J,McColl R,Black J

    更新日期:2009-07-01 00:00:00

  • Hemispheric facilitation as a result of threatening and nonthreatening words: blocked vs mixed presentation effects and order effects.

    abstract::Sixteen right-handed participants (eight male and eight female students) were administered a tachistoscopic unilateral letter-naming task. The design contained three valance conditions and two types of presentation. In baseline conditions no concurrent task was given. In threat and nonthreat conditions, each unilatera...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/s0028-3932(98)00112-2

    authors: Van Strien JW,Luipen MW

    更新日期:1999-05-01 00:00:00

  • A neuropsychological comparison of obsessive-compulsive disorder and trichotillomania.

    abstract:BACKGROUND:Obsessive-compulsive disorder (OCD) and trichotillomania (compulsive hair-pulling) share overlapping co-morbidity, familial transmission, and phenomenology. However, the extent to which these disorders share a common cognitive phenotype has yet to be elucidated using patients without confounding co-morbiditi...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2006.07.016

    authors: Chamberlain SR,Fineberg NA,Blackwell AD,Clark L,Robbins TW,Sahakian BJ

    更新日期:2007-03-02 00:00:00

  • Emotionally negative stimuli can overcome attentional deficits in patients with visuo-spatial hemineglect.

    abstract::Left unilateral spatial neglect resulting from right brain damage is characterized by loss of awareness for stimuli in the contralesional side of space, despite intact visual pathways. We examined using fMRI whether patients with neglect are more likely to consciously detect in the neglected hemifield, emotionally neg...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2011.08.006

    authors: Grabowska A,Marchewka A,Seniów J,Polanowska K,Jednoróg K,Królicki L,Kossut M,Członkowska A

    更新日期:2011-10-01 00:00:00

  • Electrophysiological correlates of detecting a visual target and detecting its absence: the role of feature dimensions.

    abstract::Electrophysiological measurements were taken from observers performing a visual search within a single feature dimension, and between multiple dimensions. The N2pc to selected singleton target stimuli (rightward tilted lines) was increased when targets varied between feature dimensions, compared to the N2pc to the sam...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2010.07.005

    authors: Akyürek EG,Dinkelbach A,Schubö A,Müller HJ

    更新日期:2010-09-01 00:00:00

  • A cognitive activation study of memory for spatial relationships.

    abstract::Twelve neurologically normal right-handed subjects were asked to remember the locations of eight representational drawings, presented one at a time, together with two landmarks (white squares), on a computer screen. Subjects were then scanned using positron emission tomography (PET) while performing forced-choice reco...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/s0028-3932(98)00136-5

    authors: Johnsrude IS,Owen AM,Crane J,Milner B,Evans AC

    更新日期:1999-06-01 00:00:00

  • Saccadic distractibility in first-episode schizophrenia.

    abstract::In the antisaccade paradigm, subjects are instructed to fixate a central point, and then move their eyes towards a position in space in the opposite direction but equidistant to a peripheral, sudden onset target. Antisaccade errors occur when subjects are "distracted" by the target and make a saccade towards it. These...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/s0028-3932(01)00145-2

    authors: Hutton SB,Joyce EM,Barnes TR,Kennard C

    更新日期:2002-01-01 00:00:00

  • Reduced specificity in emotion judgment in people with autism spectrum disorder.

    abstract::There is a conflicting literature on facial emotion processing in autism spectrum disorder (ASD): both typical and atypical performance have been reported, and inconsistencies in the literature may stem from different processes examined (emotion judgment, face perception, fixations) as well as differences in participa...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2017.03.024

    authors: Wang S,Adolphs R

    更新日期:2017-05-01 00:00:00

  • Creativity and the brain: uncovering the neural signature of conceptual expansion.

    abstract::Neurophysiological studies of creativity thus far have not allowed for clear conclusions to be made regarding the specific neural underpinnings of such complex cognition due to overgeneralizations concerning the creativity construct, heterogeneity in the type of creativity tasks used, and the questionable efficacy of ...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2012.04.015

    authors: Abraham A,Pieritz K,Thybusch K,Rutter B,Kröger S,Schweckendiek J,Stark R,Windmann S,Hermann C

    更新日期:2012-07-01 00:00:00

  • Neural mechanisms underlying spatial realignment during adaptation to optical wedge prisms.

    abstract::Visuomotor adaptation to a shift in visual input produced by prismatic lenses is an example of dynamic sensory-motor plasticity within the brain. Prism adaptation is readily induced in healthy individuals, and is thought to reflect the brain's ability to compensate for drifts in spatial calibration between different s...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2010.05.006

    authors: Chapman HL,Eramudugolla R,Gavrilescu M,Strudwick MW,Loftus A,Cunnington R,Mattingley JB

    更新日期:2010-07-01 00:00:00

  • Auditory rhyme processing in expert freestyle rap lyricists and novices: An ERP study.

    abstract::Music and language processing share and sometimes compete for brain resources. An extreme case of such shared processing occurs in improvised rap music, in which performers, or 'lyricists', combine rhyming, rhythmic, and semantic structures of language with musical rhythm, harmony, and phrasing to create integrally me...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2019.03.022

    authors: Cross K,Fujioka T

    更新日期:2019-06-01 00:00:00

  • The effect of category learning on attentional modulation of visual cortex.

    abstract::Learning about visual object categories causes changes in the way we perceive those objects. One likely mechanism by which this occurs is the application of attention to potentially relevant objects. Here we test the hypothesis that category membership influences the allocation of attention, allowing attention to be a...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2017.07.025

    authors: Folstein JR,Fuller K,Howard D,DePatie T

    更新日期:2017-09-01 00:00:00

  • Hemispheric asymmetries in discourse processing: evidence from false memories for lists and texts.

    abstract::Previous research suggests that the right hemisphere (RH) may contribute uniquely to discourse and text processing by activating and maintaining a wide range of meanings, including more distantly related meanings. The present study used the word-lists false memory paradigm [Roediger, H. L., III, & McDermott, K. B. (19...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2008.09.021

    authors: Ben-Artzi E,Faust M,Moeller E

    更新日期:2009-01-01 00:00:00

  • Dyslexics are impaired on implicit higher-order sequence learning, but not on implicit spatial context learning.

    abstract::Developmental dyslexia is characterized by poor reading ability and impairments on a range of tasks including phonological processing and processing of sensory information. Some recent studies have found deficits in implicit sequence learning using the serial reaction time task, but others have not. Other skills, such...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/j.neuropsychologia.2005.10.015

    authors: Howard JH Jr,Howard DV,Japikse KC,Eden GF

    更新日期:2006-01-01 00:00:00

  • Is handwriting posture associated with differences in motor control? An analysis of asymmetries in the readiness potential.

    abstract::Levy and Reid's [1] hypothesis that persons who write using the inverted posture have ipsilateral control of distal limb movements, particularly those involved in handwriting, was tested in three experiments in which asymmetries in the readiness potential (RP) were measured. In the first experiment, each subject execu...

    journal_title:Neuropsychologia

    pub_type: 杂志文章

    doi:10.1016/0028-3932(82)90107-5

    authors: Bashore TR,McCarthy G,Heffley EF 3rd,Clapman RM,Donchin E

    更新日期:1982-01-01 00:00:00

  • Brain activation during dichotic presentations of consonant-vowel and musical instrument stimuli: a 15O-PET study.

    abstract::Dichotic listening means that two different stimuli are presented at the same time, one in each ear. This technique is frequently used in experimental and clinical studies as a measure of hemispheric specialization. The primary aim of the present study was to record regional changes in the distribution of cerebral blo...

    journal_title:Neuropsychologia

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0028-3932(98)00101-8

    authors: Hugdahl K,Brønnick K,Kyllingsbaek S,Law I,Gade A,Paulson OB

    更新日期:1999-04-01 00:00:00